Publications by authors named "Felix Sahm"

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High 4E-BP1 expression associates with chromosome 8 gain and CDK4/6 sensitivity in Ewing sarcoma.
Cornelius M Funk, Anna C Ehlers, Martin F Orth, Karim Aljakouch, Jing Li, Felix Sahm

J Clin Invest· December 2025

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Advancing CNS tumor diagnostics with expanded DNA methylation-based classification.
Martin Sill, Daniel Schrimpf, Areeba Patel, Dominik Sturm, Natalie Jäger, Felix Sahm

Cancer Cell· December 2025

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Employing nanopore sequencing on FFPE-derived DNA for CNS tumor diagnostics.
Paul Kerbs, Michelle Brehm, Daniel Haag, Henri Bogumil, Areeba Patel, Felix Sahm

Acta Neuropathol Commun· November 2025

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Analysis of anatomical location, mitoses, and Ki-67 in 2608 meningiomas.
Anders Broechner, Andrea Daniela Maier, Christian Mirian, Felix Sahm, Stefan Hamelmann

J Neuropathol Exp Neurol· November 2025

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Loss of global DNA hypermethylation is prognostic in IDH-mutant and 1p/19q-codeleted oligodendrogliomas.
Felix E Hinz, Dennis Friedel, Franziska M Ippen, Martin Sill, Andrey Korshunov, Felix Sahm

Acta Neuropathol· November 2025

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Molecularly matched targeted therapies plus radiotherapy in glioblastoma: the phase 1/2a NM umbrella trial.
Wolfgang Wick, Lisa-Marie Lanz, Antje Wick, Inga Harting, Susan Dettmer, Felix Sahm

Nat Med· October 2025

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A spatial map of MAPK-activated immunosuppressive myeloid populations in pediatric low-grade glioma.
Augusto Faria Andrade, Romain Sigaud, Evan Puligandla, Bridget Liu, Elham Karimi, Felix Sahm

Nat Immunol· October 2025

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Tumor-associated macrophages in meningiomas: a novel biomarker for poor survival outperforming the benefits of T cells.
Catharina Lotsch, Rolf Warta, Fang Liu, Gerhard Jungwirth, Carmen Rommel, Felix Sahm

Acta Neuropathol· October 2025

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Author Correction: A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.
April A Apfelbaum, Eric Morin, Dominik Sturm, Georges Ayoub, Jeromy DiGiacomo, Felix Sahm

Nat Commun· October 2025

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The Evolving Role of TERT Alterations in Meningioma Risk Stratification.
Sybren L N Maas, Arie Perry, Felix Sahm

Neuro Oncol· October 2025

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Molecular characterization and clinical features of diffuse midline glioma in the pediatric precision oncology registry INFORM.
Elke Pfaff, Kathrin Schramm, Mirjam Blattner-Johnson, Barbara C Jones, Sebastian Stark, Felix Sahm

Acta Neuropathol· October 2025

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Integrated transcriptomic landscape of medulloblastoma and ependymoma reveals novel tumor subtype-specific biology.
Sonali Arora, Nicholas Nuechterlein, Matt Jensen, Gregory Glatzer, Philipp Sievers, Felix Sahm

Neuro Oncol· October 2025

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The effect of TERT promoter mutation on predicting meningioma outcomes: a multi-institutional cohort analysis.
Karenna J Groff, Ruchit V Patel, Yang Feng, Hia S Ghosh, Miguel A Millares Chavez, Felix Sahm

Lancet Oncol· September 2025

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Molecular and histopathological landscape of 131 meningiomas: a retrospective institutional study with insights from cIMPACT-NOW.
Rola H Ali, Abdulaziz Hassan, Hussain H Jarkhi, Abdullah Alshawish, Mohamad Almanabri, Felix Sahm

Front Oncol· September 2025

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Adult pilocytic astrocytomas: challenging the benign paradigm with surgical risks, recurrence dynamics, and molecular insights.
Dorothea Mitschang, Helena Kleineidam, Felix Hinz, Felix Sahm, Andreas Unterberg

Neurosurg Rev· September 2025

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Expansion of the spectrum of tumors diagnosed as myxopapillary ependymomas.
Fuat Kaan Aras, Dennis Friedel, Felix Keller, Ferdinand Zettl, Rouzbeh Banan, Felix Sahm

Acta Neuropathol· September 2025

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PLAG1 fusions define a third subtype of CNS embryonal tumor with PLAG family gene alteration.
Michaela-Kristina Keck, Maysa Al-Hussaini, Nisreen Amayiri, Akosua Adoma Boakye Yiadom, Gabriel Chamyan, Felix Sahm

Acta Neuropathol· August 2025

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[Lu]Lu-DOTATATE for Recurrent Meningioma (LUMEN-1, EORTC-2334-BTG): Study Protocol for a Randomized Phase II Trial.
Nathalie L Albert, Emeline Tabouret, Emilie Le Rhun, Felix Sahm, Julia Furtner

J Nucl Med· August 2025

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Correction: Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling.
Konstantin Okonechnikov, David R Ghasemi, Daniel Schrimpf, Svenja Tonn, Martin Mynarek, Felix Sahm

Acta Neuropathol Commun· August 2025

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Radiomics features from the peritumoral region can be associated with the epilepsy status of glioblastoma patients.
Yeong Chul Yun, Johann M E Jende, Katharina Holz, Sabine Wolf, Freya Garhöfer, Felix Sahm

Front Oncol· August 2025

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Distinct molecular profile and outcome of oligodendroglioma, IDH-mutant, 1p/19q-codeleted and TERTp-wildtype: a grade 1 oligodendroglioma of young patients?
Filippo Nozzoli, Ramin Rahmanzade, Simone Schmid, Leonille Schweizer, Daniel Schrimpf, Felix Sahm

Neuro Oncol· July 2025

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Integrated in vivo combinatorial functional genomics and spatial transcriptomics of tumours to decode genotype-to-phenotype relationships.
Marco Breinig, Artem Lomakin, Elyas Heidari, Michael Ritter, Gleb Rukhovich, Felix Sahm

Nat Biomed Eng· July 2025

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Prognostic value of 1D, 2D, and volumetric tumor size increases in recurrent WHO grade 2 and 3 meningiomas: Radiological post-hoc analysis of the EORTC-BTG-1320 trial.
Julia Furtner, Luzia Berchtold, Emilie Le Rhun, Antonio Silvani, Roberta Rudà, Felix Sahm

Neurooncol Adv· July 2025

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A diverse landscape of FGFR alterations and co-mutations suggests potential therapeutic strategies in pediatric low-grade gliomas.
April A Apfelbaum, Eric Morin, Dominik Sturm, Georges Ayoub, Jeromy DiGiacomo, Felix Sahm

Nat Commun· July 2025

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A feasibility study of enzymatic methylation sequencing of cell-free DNA from cerebrospinal fluid of pediatric central nervous system tumor patients for molecular classification.
Aaron Michael Taylor, Jody T Lombardi, Areeba Patel, Ariella Tamariz, Jonathan Martin, Felix Sahm

Neurooncol Adv· July 2025

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