Publications by authors named "Beat C Bornhauser"

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A clinical-stage oncology compound selectively targets drug-resistant cancers.
Kaitlin Long, Debanjan Bhattacharjee, Samuel H Newman-Stonebraker, Simon Suhr, Brandon Q Mercado, Beat C Bornhauser

bioRxiv· November 2025

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Transcriptional remodeling shapes therapeutic vulnerability to necroptosis in acute lymphoblastic leukemia.
Anna Saorin, Anna Dehler, Bartimée Galvan, Fabio Steffen, Marine Ray, Beat C Bornhauser

Blood· August 2025

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gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia.
Britt M T Vervoort, Miriam Butler, Kari J T Grünewald, Dorette S van Ingen Schenau, Trisha M Tee, Beat C Bornhauser

Haematologica· December 2024

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Caspase-2 kills cells with extra centrosomes.
Dario Rizzotto, Vincenza Vigorito, Patricia Rieder, Filip Gallob, Gian Mario Moretta, Beat C Bornhauser

Sci Adv· November 2024

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Clonal dynamics in pediatric B-cell precursor acute lymphoblastic leukemia with very early relapse.
Željko Antić, Jiangyan Yu, Beat C Bornhauser, Stefan H Lelieveld, Cedric G van der Ham

Pediatr Blood Cancer· January 2022

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A Hopeful Leap Forward by Multicentric Cooperation for Precision-Based Therapy for Very Resistant, Relapsed, or Refractory Childhood Leukemia.
Beat C Bornhauser, Jean-Pierre Bourquin

Cancer Discov· June 2021

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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Beat C Bornhauser

Autophagy· January 2021

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TNFR2 is required for RIP1-dependent cell death in human leukemia.
Júlia Aguadé-Gorgorió, Scott McComb, Cornelia Eckert, Anna Guinot, Blerim Marovca, Beat C Bornhauser

Blood Adv· October 2020

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Constitutive Activation of RAS/MAPK Pathway Cooperates with Trisomy 21 and Is Therapeutically Exploitable in Down Syndrome B-cell Leukemia.
Anouchka P Laurent, Aurélie Siret, Cathy Ignacimouttou, Kunjal Panchal, M'Boyba Diop, Beat C Bornhauser

Clin Cancer Res· July 2020

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Repurposing anthelmintic agents to eradicate resistant leukemia.
Caterina Mezzatesta, Liridon Abduli, Anna Guinot, Cornelia Eckert, Denis Schewe, Beat C Bornhauser

Blood Cancer J· June 2020

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Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7.
Scott McComb, Pik Ki Chan, Anna Guinot, Holmfridur Hartmannsdottir, Silvia Jenni, Beat C Bornhauser

Sci Adv· July 2019

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Exploiting Necroptosis for Therapy of Acute Lymphoblastic Leukemia.
Caterina Mezzatesta, Beat C Bornhauser

Front Cell Dev Biol· March 2019

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Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.
Marlies Vanden Bempt, Sofie Demeyer, Michaël Broux, Jolien De Bie, Simon Bornschein, Beat C Bornhauser

Cancer Cell· August 2018

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CD70 reverse signaling enhances NK cell function and immunosurveillance in CD27-expressing B-cell malignancies.
Mohamad F Al Sayed, Carla A Ruckstuhl, Tamara Hilmenyuk, Christina Claus, Jean-Pierre Bourquin, Beat C Bornhauser

Blood· July 2017

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Efficient Generation of Multi-gene Knockout Cell Lines and Patient-derived Xenografts Using Multi-colored Lenti-CRISPR-Cas9.
Lena Behrmann, Scott McComb, Júlia Aguadé-Gorgorió, Yun Huang, Mario Hermann, Beat C Bornhauser

Bio Protoc· April 2017

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Ex vivo drug response profiling detects recurrent sensitivity patterns in drug-resistant acute lymphoblastic leukemia.
Viktoras Frismantas, Maria Pamela Dobay, Anna Rinaldi, Joelle Tchinda, Samuel H Dunn, Beat C Bornhauser

Blood· March 2017

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Activation of concurrent apoptosis and necroptosis by SMAC mimetics for the treatment of refractory and relapsed ALL.
Scott McComb, Júlia Aguadé-Gorgorió, Lena Harder, Blerim Marovca, Gunnar Cario, Beat C Bornhauser

Sci Transl Med· May 2016

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Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support.
Jeannette Boutter, Yun Huang, Blerim Marovca, Andreas Vonderheit, Michael A Grotzer, Beat C Bornhauser

Oncotarget· November 2014

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Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases.
Michele Bernasconi, Seigo Ueda, Patricia Krukowski, Beat C Bornhauser, Kristin Ladell

Int J Cancer· November 2013

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Leukemia surfaceome analysis reveals new disease-associated features.
Paulina Mirkowska, Andreas Hofmann, Lukasz Sedek, Lucie Slamova, Ester Mejstrikova, Beat C Bornhauser

Blood· June 2013

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Tissue expression and actin binding of a novel N-terminal utrophin isoform.
Richard A Zuellig, Beat C Bornhauser, Ralf Amstutz, Bruno Constantin, Marcus C Schaub

J Biomed Biotechnol· August 2012

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Fibroblast growth factor-21 (FGF21) regulates low-density lipoprotein receptor (LDLR) levels in cells via the E3-ubiquitin ligase Mylip/Idol and the Canopy2 (Cnpy2)/Mylip-interacting saposin-like protein (Msap).
Hai Thi Do, Timofey V Tselykh, Johanna Mäkelä, Tho Huu Ho, Vesa M Olkkonen, Beat C Bornhauser

J Biol Chem· April 2012

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Guidelines for the use and interpretation of assays for monitoring autophagy.
Daniel J Klionsky, Fabio C Abdalla, Hagai Abeliovich, Robert T Abraham, Abraham Acevedo-Arozena, Beat C Bornhauser

Autophagy· April 2012

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Alternative technique for intrafemoral injection and bone marrow sampling in mouse transplant models.
Maike Schmitz, Jean-Pierre Bourquin, Beat C Bornhauser

Leuk Lymphoma· September 2011

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Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment.
Maike Schmitz, Petra Breithaupt, Nastassja Scheidegger, Gunnar Cario, Laura Bonapace, Beat C Bornhauser

Blood· August 2011

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