Publications by authors named "Beate Rohde"

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Efficacy and Safety of Zabedosertib, an Interleukin-1 Receptor-Associated Kinase 4 Inhibitor, in Patients with Moderate-to-Severe Atopic Dermatitis: A Phase II Randomized Study.
Stefan J Jodl, Margitta Worm, Frauke Friedrichs, Ulrike Heinzel-Pleines, Andrea Wagenfeld, Beate Rohde

Dermatol Ther (Heidelb)· November 2025

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Safety, Tolerability, and Pharmacokinetics of Filapixant, a Highly Selective P2X3 Receptor Antagonist, in an Ascending-Single-Dose First-in-Human Study.
Klaus Francke, Sybille Baumann, Isabella Gashaw, Stefan Klein, Beate Rohde

Pharmaceuticals (Basel)· May 2025

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Zabedosertib, a novel interleukin-1 receptor-associated kinase-4 inhibitor, shows a favorable pharmacokinetic and safety profile across multiple phase 1 studies.
Maximilian Feldmüller, Stefan J Jodl, Bart Ploeger, Andrea Wagenfeld, Herbert Wiesinger, Beate Rohde

Front Pharmacol· May 2025

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The oral IRAK4 inhibitors zabedosertib and BAY1830839 suppress local and systemic immune responses in a randomized trial in healthy male volunteers.
Stefan J Jodl, Wouter Ten Voorde, Stefan Klein, Andrea Wagenfeld, Frank S Zollmann, Beate Rohde

Clin Transl Sci· March 2024

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Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study.
Isabella Gashaw, Stefanie Reif, Herbert Wiesinger, Andreas Kaiser, Frank S Zollmann, Beate Rohde

Eur J Endocrinol· July 2023

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Pharmacokinetics and Safety of the Selective Progesterone Receptor Modulator Vilaprisan in Chinese Healthy Postmenopausal Women.
Hongzhong Liu, Ji Jiang, Zhaozhao Chen, Yunhui Zhang, Jinyi Li, Beate Rohde

Clin Pharmacol Drug Dev· May 2021

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The effects of vilaprisan on the pharmacodynamics and pharmacokinetics of a combined oral contraceptive-A randomized controlled trial.
Marcus-Hillert Schultze-Mosgau, Barbara Schütt, Corinna Draeger, Manuela Casjens, Stephanie Loewen, Beate Rohde

Br J Clin Pharmacol· March 2021

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Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women.
Rüdiger Nave, Stefan Jodl, Anja Hoffmann, Isabella Gashaw, Frank Zollmann, Beate Rohde

Reprod Sci· April 2019

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In Vivo Formation of Ethinylestradiol After Intramuscular Administration of Norethisterone Enantate.
Christian Friedrich, Matthias Berse, Stefan Klein, Beate Rohde, Joachim Höchel

J Clin Pharmacol· June 2018

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Topical administration of regorafenib eye drops: phase I dose-escalation study in healthy volunteers.
Torsten Zimmermann, Joachim Höchel, Michael Becka, Michael K Boettger, Beate Rohde

Br J Clin Pharmacol· May 2018

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Effect of the Novel Selective Progesterone Receptor Modulator Vilaprisan on Ovarian Activity in Healthy Women.
Barbara Schütt, Marcus-Hillert Schultze-Mosgau, Corinna Draeger, Xinying Chang, Stephanie Löwen, Beate Rohde

J Clin Pharmacol· February 2018

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The safety and pharmacokinetics of rapid iloprost aerosol delivery via the BREELIB nebulizer in pulmonary arterial hypertension.
Tobias Gessler, Hossein-Ardeschir Ghofrani, Matthias Held, Hans Klose, Hanno Leuchte, Beate Rohde

Pulm Circ· May 2017

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Pharmacokinetics and safety of the selective progesterone receptor modulator vilaprisan in healthy postmenopausal women
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Marcus-Hillert Schultze-Mosgau, Barbara Schuett, Frank-Thorsten Hafner, Frank Zollmann, Andreas Kaiser, Beate Rohde

Int J Clin Pharmacol Ther· January 2017

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Pharmacodynamics and safety of the novel selective progesterone receptor modulator vilaprisan: a double-blind, randomized, placebo-controlled phase 1 trial in healthy women.
Barbara Schütt, Andreas Kaiser, Marcus-Hillert Schultze-Mosgau, Christian Seitz, David Bell, Beate Rohde

Hum Reprod· August 2016

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Pharmacokinetic drug-drug interaction between ethinyl estradiol and gestodene, administered as a transdermal fertility control patch, and two CYP3A4 inhibitors and a CYP3A4 substrate.
Julia Winkler, Mark Goldammer, Matthias Ludwig, Beate Rohde, Christian Zurth

Eur J Drug Metab Pharmacokinet· December 2015

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Aβ imaging with 18F-florbetaben in prodromal Alzheimer's disease: a prospective outcome study.
Kevin T Ong, Victor L Villemagne, Alex Bahar-Fuchs, Fiona Lamb, Narelle Langdon, Beate Rohde

J Neurol Neurosurg Psychiatry· April 2015

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PET quantification of 18F-florbetaben binding to β-amyloid deposits in human brains.
Georg A Becker, Masanori Ichise, Henryk Barthel, Julia Luthardt, Marianne Patt, Beate Rohde

J Nucl Med· May 2013

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EE-drospirenone-levomefolate calcium versus EE-drospirenone + folic acid: folate status during 24 weeks of treatment and over 20 weeks following treatment cessation.
Konstanze Diefenbach, Dietmar Trummer, Frank Ebert, Michael Lissy, Manuela Koch, Beate Rohde

Int J Womens Health· April 2013

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Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women.
Hartmut Blode, Susan Zeun, Susanne Parke, Torsten Zimmermann, Beate Rohde

Contraception· October 2012

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Bioequivalence evaluation of a folate-supplemented oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium versus ethinylestradiol/drospirenone and levomefolate calcium alone.
Herbert Wiesinger, Urte Eydeler, Frank Richard, Dietmar Trummer, Hartmut Blode, Beate Rohde

Clin Drug Investig· October 2012

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Bioequivalence study of an oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium relative to ethinylestradiol/drospirenone and to levomefolate calcium alone.
Hartmut Blode, Christine Klipping, Frank Richard, Dietmar Trummer, Beate Rohde

Contraception· February 2012

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Individualized quantification of brain β-amyloid burden: results of a proof of mechanism phase 0 florbetaben PET trial in patients with Alzheimer's disease and healthy controls.
Henryk Barthel, Julia Luthardt, Georg Becker, Marianne Patt, Eva Hammerstein, Beate Rohde

Eur J Nucl Med Mol Imaging· September 2011

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Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementias.
Victor L Villemagne, Kevin Ong, Rachel S Mulligan, Gerhard Holl, Svetlana Pejoska, Beate Rohde

J Nucl Med· August 2011

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Pharmacodynamics and pharmacokinetics of inhaled iloprost, aerosolized by three different devices, in severe pulmonary hypertension.
Horst Olschewski, Beate Rohde, Jürgen Behr, Ralph Ewert, Tobias Gessler

Chest· October 2003

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