Publications by authors named "Frauke Friedrichs"

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Efficacy and Safety of Zabedosertib, an Interleukin-1 Receptor-Associated Kinase 4 Inhibitor, in Patients with Moderate-to-Severe Atopic Dermatitis: A Phase II Randomized Study.
Stefan J Jodl, Margitta Worm, Frauke Friedrichs, Ulrike Heinzel-Pleines, Andrea Wagenfeld

Dermatol Ther (Heidelb)· November 2025

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The soluble guanylate cyclase activator runcaciguat significantly improves albuminuria in patients with chronic kidney disease: a randomized placebo-controlled clinical trial.
Ron T Gansevoort, David C Wheeler, Francisco Martínez Debén, Marijn Speeckaert, Dirk Thomas, Frauke Friedrichs

Nephrol Dial Transplant· May 2025

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Pharmacokinetics and pharmacodynamics of the factor XIa-inhibiting antibody osocimab in healthy male East Asian volunteers: Results from two phase 1 studies.
Zhili Dong, Kensei Hashizume, Frauke Friedrichs, Pei Liu, Toshiaki Tanaka

Pharmacol Res Perspect· October 2024

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Pharmacokinetics, pharmacodynamics, and safety of fesomersen, a novel antisense inhibitor of factor XI, in healthy Chinese, Japanese, and Caucasian volunteers.
Tianxing Liu, Kensei Hashizume, Eva Krieg, Huijun Chen, Yuki Mukaida, Frauke Friedrichs

Clin Transl Sci· April 2024

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A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy.
Benjamin Meder, Frank Rühle, Tanja Weis, Georg Homuth, Andreas Keller, Frauke Friedrichs

Eur Heart J· April 2014

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The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease.
Jan Däbritz, Frauke Friedrichs, Toni Weinhage, Jochen Hampe, Torsten Kucharzik

Am J Physiol Gastrointest Liver Physiol· May 2011

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HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy.
Frauke Friedrichs, Christian Zugck, Gerd-Jörg Rauch, Boris Ivandic, Dieter Weichenhan

Genome Res· March 2009

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Impact of inherited thrombophilia on venous thromboembolism in children: a systematic review and meta-analysis of observational studies.
Guy Young, Manuela Albisetti, Mariana Bonduel, Leonardo Brandao, Anthony Chan, Frauke Friedrichs

Circulation· September 2008

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The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network.
Frauke Friedrichs, Liesbet Henckaerts, Severine Vermeire, Torsten Kucharzik, Tanja Seehafer

J Mol Med (Berl)· April 2008

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Effects of primary and secondary prophylaxis on the clinical expression of joint damage in children with severe haemophilia A. Results of a multicenter non-concurrent cohort study.
Rosemarie Schobess, Karin Kurnik, Frauke Friedrichs, Susan Halimeh, Anne Krümpel

Thromb Haemost· January 2008

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CRP gene haplotypes, serum CRP, and cerebral small-vessel disease: the Rotterdam Scan Study and the MEMO Study.
Christiane Reitz, Klaus Berger, Moniek P M de Maat, Monika Stoll, Frauke Friedrichs

Stroke· August 2007

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DLG5 R30Q variant is a female-specific protective factor in pediatric onset Crohn's disease.
Vincent Biank, Frauke Friedrichs, Umesh Babusukumar, Tao Wang, Monika Stoll

Am J Gastroenterol· February 2007

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Role of discs large homolog 5.
Frauke Friedrichs, Monika Stoll

World J Gastroenterol· June 2006

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Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men.
Frauke Friedrichs, Sonia Brescianini, Vito Annese, Anna Latiano, Klaus Berger

Hum Genet· April 2006

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