Publications by authors named "Georg Homuth"

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A methylome-wide association study of major depression with out-of-sample case-control classification and trans-ancestry comparison.
Xueyi Shen, Miruna Barbu, Doretta Caramaschi, Ryan Arathimos, Darina Czamara, Georg Homuth

Nat Ment Health· September 2025

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Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects.
Worrawat Engchuan, Omar Shanta, Kuldeep Kumar, Jeffrey R MacDonald, Bhooma Thiruvahindrapuram, Georg Homuth

medRxiv· July 2025

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A cross-disorder analysis of CNVs finds novel loci and dose-dependent relationships of genes to psychiatric traits.
Omar Shanta, Marieke Klein, Molly Sacks, Jeffrey R MacDonald, Adam Maihofer, Georg Homuth

medRxiv· July 2025

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Multi-ancestry genome-wide association analyses incorporating SNP-by-psychosocial interactions identify novel loci for serum lipids.
Amy R Bentley, Michael R Brown, Solomon K Musani, Karen L Schwander, Thomas W Winkler, Georg Homuth

Transl Psychiatry· June 2025

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Translational genomics of osteoarthritis in 1,962,069 individuals.
Konstantinos Hatzikotoulas, Lorraine Southam, Lilja Stefansdottir, Cindy G Boer, Merry-Lynn McDonald, Georg Homuth

Nature· May 2025

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Associations between common genetic variants and income provide insights about the socio-economic health gradient.
Hyeokmoon Kweon, Casper A P Burik, Yuchen Ning, Rafael Ahlskog, Charley Xia, Georg Homuth

Nat Hum Behav· April 2025

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Identifying genetic differences between bipolar disorder and major depression through multiple genome-wide association analyses.
Georgia Panagiotaropoulou, Kajsa-Lotta Georgii Hellberg, Jonathan R I Coleman, Darsol Seok, Janos Kalman, Georg Homuth

Br J Psychiatry· February 2025

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Lower cardiorespiratory fitness is associated with an altered gut microbiome. The Study of Health in Pomerania (SHIP).
Marcello Ricardo Paulista Markus, Frank-Ulrich Weiss, Johannes Hertel, Stefan Weiss, Malte Rühlemann, Georg Homuth

Sci Rep· February 2025

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A Large-Scale Genome-wide Association Study of Blood Pressure Accounting for Gene-Depressive Symptomatology Interactions in 564,680 Individuals from Diverse Populations.
Songmi Lee, Clint L Miller, Amy R Bentley, Michael R Brown, Pavithra Nagarajan, Georg Homuth

Res Sq· February 2025

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Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
Luis M García-Marín, Adrian I Campos, Santiago Diaz-Torres, Jill A Rabinowitz, Zuriel Ceja, Georg Homuth

Nat Genet· November 2024

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XModNN: Explainable Modular Neural Network to Identify Clinical Parameters and Disease Biomarkers in Transcriptomic Datasets.
Jan Oldenburg, Jonas Wagner, Sascha Troschke-Meurer, Jessica Plietz, Lars Kaderali, Georg Homuth

Biomolecules· November 2024

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Fecal glycoprotein 2 is a marker of gut microbiota dysbiosis and systemic inflammation.
Fabian Frost, Stefan Weiss, Johannes Hertel, Malte Rühlemann, Corinna Bang, Georg Homuth

Gut Pathog· October 2024

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RIOK2 transcriptionally regulates TRiC and dyskerin complexes to prevent telomere shortening.
Shrestha Ghosh, Mileena T Nguyen, Ha Eun Choi, Maximilian Stahl, Annemarie Luise Kühn, Georg Homuth

Nat Commun· August 2024

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Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.
Luis M García-Marín, Adrian I Campos, Santiago Diaz-Torres, Jill A Rabinowitz, Zuriel Ceja, Georg Homuth

medRxiv· August 2024

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Distinct genetic liability profiles define clinically relevant patient strata across common diseases.
Lucia Trastulla, Georgii Dolgalev, Sylvain Moser, Laura T Jiménez-Barrón, Till F M Andlauer, Georg Homuth

Nat Commun· July 2024

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Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Nick Shrine, Anna L Guyatt, A Mesut Erzurumluoglu, Victoria E Jackson, Brian D Hobbs, Georg Homuth

Nat Genet· May 2024

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Genetic variants for head size share genes and pathways with cancer.
Maria J Knol, Raymond A Poot, Tavia E Evans, Claudia L Satizabal, Aniket Mishra, Georg Homuth

Cell Rep Med· May 2024

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Multi-omics and pathway analyses of genome-wide associations implicate regulation and immunity in verbal declarative memory performance.
Hao Mei, Jeannette Simino, Lianna Li, Fan Jiang, Joshua C Bis, Georg Homuth

Alzheimers Res Ther· January 2024

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Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders.
Nora L Großmann, Antoine Weihs, Luise Kühn, Susann Sauer, Simone Röh, Georg Homuth

Int J Mol Sci· January 2024

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Identifying genetic differences between bipolar disorder and major depression through multiple GWAS.
Georgia Panagiotaropoulou, Kajsa-Lotta Georgii Hellberg, Jonathan R I Coleman, Darsol Seok, Janos Kalman, Georg Homuth

medRxiv· January 2024

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Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci.
Lisa de las Fuentes, Karen L Schwander, Michael R Brown, Amy R Bentley, Thomas W Winkler, Georg Homuth

Front Genet· November 2023

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Genome-wide association study of Helicobacter pylori serological status in Latin American children.
Iasmin Souza Lima, Thiago Magalhães da Silva, Stefan Weiss, Georg Homuth, Markus M Lerch

Helicobacter· October 2023

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Author Correction: Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.
Nick Shrine, Abril G Izquierdo, Jing Chen, Richard Packer, Robert J Hall, Georg Homuth

Nat Genet· October 2023

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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation.
Ashley Budu-Aggrey, Anna Kilanowski, Maria K Sobczyk, , Suyash S Shringarpure, Georg Homuth

Nat Commun· October 2023

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Toxin exposure and HLA alleles determine serum antibody binding to toxic shock syndrome toxin 1 (TSST-1) of .
Stefan Weiss, Silva Holtfreter, Tanja C Meyer, Frieder Schmiedeke, Clemens Cammann, Georg Homuth

Front Immunol· September 2023

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