Publications by authors named "Benjamin Beaufils"

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Liposomal Irinotecan Shows a Larger Therapeutic Index than Non-liposomal Irinotecan in Patient-Derived Xenograft Models of Pancreatic Cancer.
Sandrine Barbier, Benjamin Beaufils, Ricardo de Miguel, Melissa Reyre, Yannick Le Meitour

Oncol Ther· March 2023

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Augmenting Experimental Gastric Cancer Activity of Irinotecan through Liposomal Formulation and Antiangiogenic Combination Therapy.
Niranjan Awasthi, Margaret A Schwarz, Changhua Zhang, Stephan G Klinz, Florence Meyer-Losic, Benjamin Beaufils

Mol Cancer Ther· July 2022

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Fc Sialylation Prolongs Serum Half-Life of Therapeutic Antibodies.
Mathilde Bas, Aurélie Terrier, Emilie Jacque, Aurélie Dehenne, Virginie Pochet-Béghin, Benjamin Beaufils

J Immunol· March 2019

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The discovery of potent and selective kynurenine 3-monooxygenase inhibitors for the treatment of acute pancreatitis.
John Liddle, Benjamin Beaufils, Margaret Binnie, Anne Bouillot, Alexis A Denis

Bioorg Med Chem Lett· May 2017

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Development of a Series of Kynurenine 3-Monooxygenase Inhibitors Leading to a Clinical Candidate for the Treatment of Acute Pancreatitis.
Ann L Walker, Nicolas Ancellin, Benjamin Beaufils, Marylise Bergeal, Margaret Binnie

J Med Chem· April 2017

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Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.
Damian J Mole, Scott P Webster, Iain Uings, Xiaozhong Zheng, Margaret Binnie, Benjamin Beaufils

Nat Med· February 2016

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The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits.
Sophie M Bertrand, Nicolas Ancellin, Benjamin Beaufils, Ryan P Bingham, Jennifer A Borthwick

J Med Chem· September 2015

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Discovery of Pyridones As Oral AMPK Direct Activators.
Olivier Mirguet, Stéphane Sautet, Catherine-Anne Clément, Jérôme Toum, Frédéric Donche, Benjamin Beaufils

ACS Med Chem Lett· July 2013

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Regulation of the oligopeptide transporter, PEPT-1, in DSS-induced rat colitis.
Genia Radeva, Marion Buyse, Patrick Hindlet, Benjamin Beaufils, Francine Walker

Dig Dis Sci· July 2007

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