Publications by authors named "Benjamin D Sachs"

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Sub-chronic stress exerts partially distinct behavioral and epigenetic effects in male and female mice.
Matthew J Domanico, Sophie Stevens, Iris Wainston, Emily Khoo, Corey McCall, Benjamin D Sachs

Front Behav Neurosci· October 2025

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The effects of brain serotonin deficiency on the behavioral and neurogenesis-promoting effects of voluntary exercise in tryptophan hydroxylase 2 (R439H) knock-in mice.
Allison K Warner, Lauren Iskander, Kristen Allen, Isabella Quatela, Hannah Borrelli, Benjamin D Sachs

Neuropharmacology· November 2024

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Genetic loss of the dopamine transporter significantly impacts behavioral and molecular responses to sub-chronic stress in mice.
Avelina Petri, Abigail Sullivan, Kristen Allen, Benjamin D Sachs

Front Mol Neurosci· February 2024

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Estrogen administration and withdrawal in a model of hormone-simulated pregnancy lead to alterations in behavior and gene expression but do not induce depression-like phenotypes in mice.
Kerry Buckhaults, Benjamin D Swack, Benjamin D Sachs

Physiol Behav· October 2023

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Brain serotonin deficiency and fluoxetine lead to sex-specific effects on binge-like food consumption in mice.
Melinda D Karth, Brittany J Baugher, Sophia A Pellechia, Shama N Huq, Allison K Warner, Benjamin D Sachs

Psychopharmacology (Berl)· September 2022

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Early life maternal separation induces sex-specific antidepressant-like responses but has minimal effects on adult stress susceptibility in mice.
Brittany J Baugher, Benjamin D Sachs

Front Behav Neurosci· September 2022

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Chronic, but not sub-chronic, stress increases binge-like alcohol consumption in male and female c57BL6 mice.
William McCarthy, Shama N Huq, Kristen Allen, Lindsay Scally, Avelina Petri, Benjamin D Sachs

Front Behav Neurosci· September 2022

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Sub-chronic stress induces similar behavioral effects in male and female mice despite sex-specific molecular adaptations in the nucleus accumbens.
Brittany J Baugher, Kerry Buckhaults, Jordan Case, Abigail Sullivan, Shama N Huq, Benjamin D Sachs

Behav Brain Res· May 2022

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The Effects of Brain Serotonin Deficiency on Responses to High Fat Diet in Female Mice.
Shama N Huq, Allison K Warner, Kerry Buckhaults, Benjamin D Sachs

Front Neurosci· July 2021

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Brain 5-HT Deficiency Prevents Antidepressant-Like Effects of High-Fat-Diet and Blocks High-Fat-Diet-Induced GSK3β Phosphorylation in the Hippocampus.
Michelle M Karth, Brittany J Baugher, Nicole Daly, Melinda D Karth, Stephen C Gironda, Benjamin D Sachs

Front Mol Neurosci· December 2019

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Slow-release delivery enhances the pharmacological properties of oral 5-hydroxytryptophan: mouse proof-of-concept.
Jacob P R Jacobsen, Adrianna Oh, Rachel Bangle, Wendy L Roberts, Elizabeth L Royer, Benjamin D Sachs

Neuropsychopharmacology· November 2019

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Brain-region-specific Molecular Responses to Maternal Separation and Social Defeat Stress in Mice.
Benjamin D Sachs, Ha L Tran, Emily Folse, Marc G Caron

Neuroscience· March 2018

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Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability.
Rainbo Hultman, Kyle Ulrich, Benjamin D Sachs, Cameron Blount, David E Carlson

Cell· March 2018

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SSRI Augmentation by 5-Hydroxytryptophan Slow Release: Mouse Pharmacodynamic Proof of Concept.
Jacob Pr Jacobsen, Meghan L Rudder, Wendy Roberts, Elizabeth L Royer, Taylor J Robinson, Benjamin D Sachs

Neuropsychopharmacology· August 2016

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p75 Neurotrophin Receptor Regulates Energy Balance in Obesity.
Bernat Baeza-Raja, Benjamin D Sachs, Pingping Li, Frank Christian, Eirini Vagena

Cell Rep· January 2016

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Serotonin deficiency alters susceptibility to the long-term consequences of adverse early life experience.
Benjamin D Sachs, Ramona M Rodriguiz, Ha L Tran, Akshita Iyer, William C Wetsel

Psychoneuroendocrinology· March 2015

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Brain 5-HT deficiency increases stress vulnerability and impairs antidepressant responses following psychosocial stress.
Benjamin D Sachs, Jason R Ni, Marc G Caron

Proc Natl Acad Sci U S A· February 2015

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The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse.
Jacob P R Jacobsen, Per Plenge, Benjamin D Sachs, Alan L Pehrson, Manuel Cajina

Psychopharmacology (Berl)· December 2014

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Chronic fluoxetine increases extra-hippocampal neurogenesis in adult mice.
Benjamin D Sachs, Marc G Caron

Int J Neuropsychopharmacol· October 2014

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Congenital brain serotonin deficiency leads to reduced ethanol sensitivity and increased ethanol consumption in mice.
Benjamin D Sachs, A Ayten Salahi, Marc G Caron

Neuropharmacology· February 2014

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Sex differences in response to chronic mild stress and congenital serotonin deficiency.
Benjamin D Sachs, Jason R Ni, Marc G Caron

Psychoneuroendocrinology· February 2014

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The effects of brain serotonin deficiency on behavioural disinhibition and anxiety-like behaviour following mild early life stress.
Benjamin D Sachs, Ramona M Rodriguiz, William B Siesser, Alexander Kenan, Elizabeth L Royer

Int J Neuropsychopharmacol· October 2013

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Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency.
Kafui Dzirasa, Sunil Kumar, Benjamin D Sachs, Marc G Caron, Miguel A L Nicolelis

J Neurosci· March 2013

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Pharmacological blockade of a β(2)AR-β-arrestin-1 signaling cascade prevents the accumulation of DNA damage in a behavioral stress model.
Makoto R Hara, Benjamin D Sachs, Marc G Caron, Robert J Lefkowitz

Cell Cycle· January 2013

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Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice.
William B Siesser, Benjamin D Sachs, Amy J Ramsey, Tatyana D Sotnikova, Jean-Martin Beaulieu

ACS Chem Neurosci· January 2013

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