Publications by authors named "Benjamin Escher"

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Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop.
Laura Job, Anja Köhler, Andreas Eichinger, Mauricio Testanera, Benjamin Escher

Biochemistry· February 2023

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Engineering of a phosphotriesterase with improved stability and enhanced activity for detoxification of the pesticide metabolite malaoxon.
Laura Job, Anja Köhler, Mauricio Testanera, Benjamin Escher, Franz Worek

Protein Eng Des Sel· January 2023

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cART Restores Transient Responsiveness to IFN Type 1 in HIV-Infected Humanized Mice.
Maarja Gruenbach, Christina K S Muller, Erika Schlaepfer, Luca Baroncini, Doris Russenberger, Benjamin Escher

J Virol· November 2022

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Post-VX exposure treatment of rats with engineered phosphotriesterases.
Lisa Stigler, Anja Köhler, Marianne Koller, Laura Job, Benjamin Escher

Arch Toxicol· February 2022

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Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro.
Anja Köhler, Benjamin Escher, Laura Job, Marianne Koller, Horst Thiermann

Arch Toxicol· August 2021

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Translating the Concept of Bispecific Antibodies to Engineering Heterodimeric Phosphotriesterases with Broad Organophosphate Substrate Recognition.
Benjamin Escher, Anja Köhler, Laura Job, Franz Worek, Arne Skerra

Biochemistry· November 2020

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A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds.
Laura Job, Anja Köhler, Benjamin Escher, Franz Worek, Arne Skerra

Toxicol Lett· March 2020

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