Publications by authors named "Laura Job"

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Structural and Functional Analysis of a Highly Active Designed Phosphotriesterase for the Detoxification of Organophosphate Nerve Agents Reveals an Unpredicted Conformation of the Active Site Loop.
Laura Job, Anja Köhler, Andreas Eichinger, Mauricio Testanera, Benjamin Escher

Biochemistry· February 2023

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Engineering of a phosphotriesterase with improved stability and enhanced activity for detoxification of the pesticide metabolite malaoxon.
Laura Job, Anja Köhler, Mauricio Testanera, Benjamin Escher, Franz Worek

Protein Eng Des Sel· January 2023

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Post-VX exposure treatment of rats with engineered phosphotriesterases.
Lisa Stigler, Anja Köhler, Marianne Koller, Laura Job, Benjamin Escher

Arch Toxicol· February 2022

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Inhibition of an organophosphate-detoxifying bacterial phosphotriesterase by albumin and plasma thiol components.
Anja Köhler, Laura Job, Franz Worek, Arne Skerra

Toxicol Lett· October 2021

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Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro.
Anja Köhler, Benjamin Escher, Laura Job, Marianne Koller, Horst Thiermann

Arch Toxicol· August 2021

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Breast cancer survival in Brazil: How much health care access impact on cancer outcomes?
Maira Caleffi, Isabel Crivelatti, Norah A Burchardt, Rodrigo A Ribeiro, Yulieth Acevedo, Laura Gianotti Job

Breast· December 2020

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Translating the Concept of Bispecific Antibodies to Engineering Heterodimeric Phosphotriesterases with Broad Organophosphate Substrate Recognition.
Benjamin Escher, Anja Köhler, Laura Job, Franz Worek, Arne Skerra

Biochemistry· November 2020

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A catalytic bioscavenger with improved stability and reduced susceptibility to oxidation for treatment of acute poisoning with neurotoxic organophosphorus compounds.
Laura Job, Anja Köhler, Benjamin Escher, Franz Worek, Arne Skerra

Toxicol Lett· March 2020

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Time-course and degradation rate of membrane scaffold protein (MSP1D1) during recombinant production.
Ramona Faas, Dirk Kiefer, Laura Job, Annelie Pohle, Karin Moß

Biotechnol Rep (Amst)· March 2018

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New system to predict chemotherapeutic efficacy of drug combinations in fresh tumor samples.
Frank Christian Kischkel, Julia Eich, Carina I Meyer, Paula Weidemüller, Jens Krapfl, Laura Job

PeerJ· March 2017

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