Publications by authors named "Benjamin Hackner"

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A rapid screening system evaluates novel inhibitors of DNA methylation and suggests F-box proteins as potential therapeutic targets for high-risk neuroblastoma.
Livius Penter, Bert Maier, Ute Frede, Benjamin Hackner, Thomas Carell

Target Oncol· December 2015

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Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues.
Mirko Wagner, Jessica Steinbacher, Theo F J Kraus, Stylianos Michalakis, Benjamin Hackner

Angew Chem Int Ed Engl· October 2015

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Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
Toni Pfaffeneder, Fabio Spada, Mirko Wagner, Caterina Brandmayr, Silvia K Laube, Benjamin Hackner

Nat Chem Biol· July 2014

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Targeted mutagenesis results in an activation of DNA methyltransferase 1 and confirms an autoinhibitory role of its RFTS domain.
Pavel Bashtrykov, Arumugam Rajavelu, Benjamin Hackner, Sergey Ragozin, Thomas Carell

Chembiochem· March 2014

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Deamination, oxidation, and C-C bond cleavage reactivity of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine.
Stefan Schiesser, Toni Pfaffeneder, Keyarash Sadeghian, Benjamin Hackner, Barbara Steigenberger

J Am Chem Soc· October 2013

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Synthesis of 5-hydroxymethyl-, 5-formyl-, and 5-carboxycytidine-triphosphates and their incorporation into oligonucleotides by polymerase chain reaction.
Barbara Steigenberger, Stefan Schiesser, Benjamin Hackner, Caterina Brandmayr, Silvia K Laube

Org Lett· January 2013

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Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors.
Theo F J Kraus, Daniel Globisch, Mirko Wagner, Sabina Eigenbrod, David Widmann, Benjamin Hackner

Int J Cancer· October 2012

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Mechanism and stem-cell activity of 5-carboxycytosine decarboxylation determined by isotope tracing.
Stefan Schiesser, Benjamin Hackner, Toni Pfaffeneder, Markus Müller, Christian Hagemeier

Angew Chem Int Ed Engl· June 2012

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The discovery of 5-formylcytosine in embryonic stem cell DNA.
Toni Pfaffeneder, Benjamin Hackner, Matthias Truss, Martin Münzel, Markus Müller

Angew Chem Int Ed Engl· July 2011

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