Publications by authors named "Benjamin Newcomb"

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Retention of lysosomal acid sphingomyelinase protects from Niemann-Pick Disease.
Cameron A Beard, Kyra N Hermanson, Justin M Snider, Aki Hara, Brandon K Dahl, Benjamin Newcomb

Neurobiol Dis· November 2025

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Healthcare Provider Perspectives on HIV Cure Research in Ghana.
Helena Lamptey, Benjamin Newcomb, Evelyn Y Bonney, James O Aboagye, Peter Puplampu

AIDS Res Treat· May 2023

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Sublethal doxorubicin promotes migration and invasion of breast cancer cells: role of Src Family non-receptor tyrosine kinases.
Samia Mohammed, Achraf A Shamseddine, Benjamin Newcomb, Ronald S Chavez, Tyler D Panzner

Breast Cancer Res· July 2021

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Targeting acid ceramidase inhibits YAP/TAZ signaling to reduce fibrosis in mice.
Sarah Alsamman, Stephanie A Christenson, Amy Yu, Nadia M E Ayad, Meghan S Mooring, Benjamin Newcomb

Sci Transl Med· August 2020

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Identification of an acid sphingomyelinase ceramide kinase pathway in the regulation of the chemokine CCL5.
Benjamin Newcomb, Cosima Rhein, Izolda Mileva, Rasheed Ahmad, Christopher J Clarke

J Lipid Res· July 2018

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Tricyclic Antidepressants Promote Ceramide Accumulation to Regulate Collagen Production in Human Hepatic Stellate Cells.
Jennifer Y Chen, Benjamin Newcomb, Chan Zhou, Joshua V Pondick, Sarani Ghoshal

Sci Rep· March 2017

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Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
Jieqi Wang, Jan Eike Wegener, Teng-Wei Huang, Smitha Sripathy, Hector De Jesus-Cortes, Benjamin Newcomb

Nature· September 2015

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A new twist to the emerging functions of ceramides in cancer: novel role for platelet acid sphingomyelinase in cancer metastasis.
Yusuf A Hannun, Benjamin Newcomb

EMBO Mol Med· June 2015

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Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.
Jieqi Wang, Jan Eike Wegener, Teng-Wei Huang, Smitha Sripathy, Hector De Jesus-Cortes, Benjamin Newcomb

Nature· May 2015

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Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs.
Aiping Bai, Zdzislaw M Szulc, Jacek Bielawski, Jason S Pierce, Barbara Rembiesa, Benjamin Newcomb

Bioorg Med Chem· December 2014

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Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway.
David M Perry, Benjamin Newcomb, Mohamad Adada, Bill X Wu, Patrick Roddy

J Biol Chem· August 2014

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The plant decapeptide OSIP108 prevents copper-induced apoptosis in yeast and human cells.
Pieter Spincemaille, Gursimran Chandhok, Benjamin Newcomb, Jef Verbeek, Kim Vriens

Biochim Biophys Acta· June 2014

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Distinct signaling roles of ceramide species in yeast revealed through systematic perturbation and systems biology analyses.
David J Montefusco, Lujia Chen, Nabil Matmati, Songjian Lu, Benjamin Newcomb

Sci Signal· October 2013

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Sphingoid bases and the serine catabolic enzyme CHA1 define a novel feedforward/feedback mechanism in the response to serine availability.
David J Montefusco, Benjamin Newcomb, Jason L Gandy, Sarah E Brice, Nabil Matmati

J Biol Chem· March 2012

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Identification of inhibitors of chromatin modifying enzymes using the yeast phenotypic screens.
Benjamin Newcomb, Antonio Bedalov

Methods Mol Biol· July 2009

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Hst3 is regulated by Mec1-dependent proteolysis and controls the S phase checkpoint and sister chromatid cohesion by deacetylating histone H3 at lysine 56.
Safia Thaminy, Benjamin Newcomb, Jessica Kim, Tonibelle Gatbonton, Eric Foss

J Biol Chem· December 2007

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