Publications by authors named "Patrick Roddy"

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Anti-Ferroptotic Treatment Deteriorates Myocardial Infarction by Inhibiting Angiogenesis and Altering Immune Response.
Rebecca A Stairley, Allison M Trouten, Shuang Li, Patrick L Roddy, Kristine Y DeLeon-Pennell

Antioxidants (Basel)· June 2024

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Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury.
Mary E Mohr, Shuang Li, Allison M Trouten, Rebecca A Stairley, Patrick L Roddy

iScience· March 2024

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Cardiomyocyte-fibroblast interaction regulates ferroptosis and fibrosis after myocardial injury.
Mary E Mohr, Shuang Li, Allison M Trouten, Rebecca A Stairley, Patrick L Roddy

bioRxiv· February 2023

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Depletion of adipocyte sphingosine kinase 1 leads to cell hypertrophy, impaired lipolysis, and nonalcoholic fatty liver disease.
Andrea K Anderson, Johana M Lambert, David J Montefusco, Bao Ngan Tran, Patrick Roddy

J Lipid Res· October 2020

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Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes.
Brittany A Law, Xianghai Liao, Kelsey S Moore, Abigail Southard, Patrick Roddy

FASEB J· March 2018

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Reducing FLI1 levels in the MRL/lpr lupus mouse model impacts T cell function by modulating glycosphingolipid metabolism.
Erin Morris Richard, Thirumagal Thiyagarajan, Marlene A Bunni, Fahmin Basher, Patrick O Roddy

PLoS One· February 2015

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Sustained activation of protein kinase C induces delayed phosphorylation and regulates the fate of epidermal growth factor receptor.
Mengling Liu, Jolanta Idkowiak-Baldys, Patrick L Roddy, Aleksander Baldys, John Raymond

PLoS One· February 2015

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Defining a role for acid sphingomyelinase in the p38/interleukin-6 pathway.
David M Perry, Benjamin Newcomb, Mohamad Adada, Bill X Wu, Patrick Roddy

J Biol Chem· August 2014

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Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation.
K Alexa Orr Gandy, Mohamad Adada, Daniel Canals, Brittany Carroll, Patrick Roddy

FASEB J· August 2013

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Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins.
K Alexa Orr Gandy, Daniel Canals, Mohamad Adada, Masayuki Wada, Patrick Roddy

Biochem J· February 2013

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Identification and characterization of protein phosphatase 2C activation by ceramide.
David M Perry, Kazuyuki Kitatani, Patrick Roddy, Mohamad El-Osta, Yusuf A Hannun

J Lipid Res· August 2012

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Protein phosphatase 1α mediates ceramide-induced ERM protein dephosphorylation: a novel mechanism independent of phosphatidylinositol 4, 5-biphosphate (PIP2) and myosin/ERM phosphatase.
Daniel Canals, Patrick Roddy, Yusuf A Hannun

J Biol Chem· March 2012

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Neutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells.
Christopher J Clarke, Emily A Cloessner, Patrick L Roddy, Yusuf A Hannun

Biochem J· April 2011

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Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase.
Russell W Jenkins, Christopher J Clarke, Daniel Canals, Ashley J Snider, Christopher R Gault, Patrick Roddy

J Biol Chem· April 2011

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A novel mechanism of lysosomal acid sphingomyelinase maturation: requirement for carboxyl-terminal proteolytic processing.
Russell W Jenkins, Jolanta Idkowiak-Baldys, Fabio Simbari, Daniel Canals, Patrick Roddy

J Biol Chem· February 2011

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Regulated secretion of acid sphingomyelinase: implications for selectivity of ceramide formation.
Russell W Jenkins, Daniel Canals, Jolanta Idkowiak-Baldys, Fabio Simbari, Patrick Roddy

J Biol Chem· November 2010

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Differential effects of ceramide and sphingosine 1-phosphate on ERM phosphorylation: probing sphingolipid signaling at the outer plasma membrane.
Daniel Canals, Russell W Jenkins, Patrick Roddy, María José Hernández-Corbacho, Lina M Obeid

J Biol Chem· October 2010

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Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5.
Bill X Wu, Vinodh Rajagopalan, Patrick L Roddy, Christopher J Clarke, Yusuf A Hannun

J Biol Chem· June 2010

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Identification of a novel amidase motif in neutral ceramidase.
Sehamuddin Galadari, Bill X Wu, Cungui Mao, Patrick Roddy, Samer El Bawab

Biochem J· February 2006

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Identification of two RNA cis-elements that function to regulate the 5' splice site selection of Bcl-x pre-mRNA in response to ceramide.
Autumn Massiello, Arelis Salas, Ryan L Pinkerman, Patrick Roddy, James R Roesser

J Biol Chem· April 2004

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The structural requirements for ceramide activation of serine-threonine protein phosphatases.
Charles E Chalfant, Zdzislaw Szulc, Patrick Roddy, Alicja Bielawska, Yusuf A Hannun

J Lipid Res· March 2004

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Ceramide 1-phosphate is a direct activator of cytosolic phospholipase A2.
Benjamin J Pettus, Alicja Bielawska, Preeti Subramanian, Dayanjan S Wijesinghe, Michael Maceyka, Patrick Roddy

J Biol Chem· March 2004

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Ceramide kinase mediates cytokine- and calcium ionophore-induced arachidonic acid release.
Benjamin J Pettus, Alicja Bielawska, Sarah Spiegel, Patrick Roddy, Yusuf A Hannun

J Biol Chem· October 2003

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Substrate specificity of rat brain ceramidase.
Samer El Bawab, Julnar Usta, Patrick Roddy, Zdzislaw M Szulc, Alicja Bielawska

J Lipid Res· January 2002

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