Publications by authors named "Benoit Chevalier"

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In silico, in vitro and ex vivo characterization of cystic fibrosis transmembrane conductance regulator pathogenic variants localized in the fourth intracellular loop and their rescue by modulators.
Emanuela Pesce, Valeria Tomati, Valeria Capurro, Mariateresa Lena, Cristina Pastorino, Benoit Chevalier

Br J Pharmacol· December 2025

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Beyond Trikafta: new models to assess tissue dependent rescue of N1303K-CFTR.
Iwona Pranke, Valeria Capurro, Benoit Chevalier, Emanuela Pesce, Valeria Tomati

Front Pharmacol· November 2025

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CFTR correctors potentiate gating mutants causing cystic fibrosis.
Solène Castanier, Ahmad Elbahnsi, Benoit Chevalier, Lynda Berri, Madara Dias Wickramanayaka

J Cyst Fibros· November 2025

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Novel gain-of-function mutants identify a critical region within CFTR membrane-spanning domain 2 controlling cAMP-dependent and ATP-independent channel activation.
Solène Castanier, Ahmad Elbahnsi, Benoit Chevalier, Nesrine Baatallah, Iwona Pranke

Cell Mol Life Sci· October 2024

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Role of KCNK3 Dysfunction in Dasatinib-associated Pulmonary Arterial Hypertension and Endothelial Cell Dysfunction.
Hélène Le Ribeuz, Anaïs Saint-Martin Willer, Benoit Chevalier, Maria Sancho, Bastien Masson

Am J Respir Cell Mol Biol· July 2024

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Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells.
Mattijs Bulcaen, Phéline Kortleven, Ronald B Liu, Giulia Maule, Elise Dreano, Benoit Chevalier

Cell Rep Med· May 2024

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Effects of skin-to-skin contact in supported diagonal flexion positioning on movement quality in very preterm infants at term age.
Aude Buil, Nelly Thomas, Benoît Chevalier, Emmanuel Devouche

Early Hum Dev· March 2024

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Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium.
Miroslaw Zajac, Agathe Lepissier, Elise Dréano, Benoit Chevalier, Aurélie Hatton

Front Pharmacol· December 2023

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Nonsense mutations accelerate lung disease and decrease survival of cystic fibrosis children.
Annalisa Orenti, Iwona Pranke, Caroline Faucon, Jessica Varilh, Aurelie Hatton, Benoit Chevalier

J Cyst Fibros· November 2023

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Theratyping cystic fibrosis patients to guide elexacaftor/tezacaftor/ivacaftor out-of-label prescription.
Elise Dreano, Pierre Régis Burgel, Aurelie Hatton, Naim Bouazza, Benoit Chevalier

Eur Respir J· October 2023

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The U UGA C sequence provides a favorable context to ELX-02 induced CFTR readthrough.
Iwona M Pranke, Jessica Varilh, Aurélie Hatton, Caroline Faucon, Emmanuelle Girodon, Benoit Chevalier

J Cyst Fibros· May 2023

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Design of Crotoxin-Based Peptides with Potentiator Activity Targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator.
Marc Ravatin, Norbert Odolczyk, Nathalie Servel, J Iñaki Guijarro, Eric Tagat, Benoit Chevalier

J Mol Biol· February 2023

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Acting on the CFTR Membrane-Spanning Domains Interface Rescues Some Misfolded Mutants.
Nesrine Baatallah, Ahmad Elbahnsi, Benoit Chevalier, Solène Castanier, Jean-Paul Mornon

Int J Mol Sci· December 2022

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Keratin 8 is a scaffolding and regulatory protein of ERAD complexes.
Iwona Maria Pranke, Benoit Chevalier, Aiswarya Premchandar, Nesrine Baatallah, Kamil F Tomaszewski

Cell Mol Life Sci· September 2022

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Pharmacological chaperone-rescued cystic fibrosis CFTR-F508del mutant overcomes PRAF2-gated access to endoplasmic reticulum exit sites.
Kusumika Saha, Benoit Chevalier, Stéphane Doly, Nesrine Baatallah, Thomas Guilbert

Cell Mol Life Sci· September 2022

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Differential CFTR-Interactome Proximity Labeling Procedures Identify Enrichment in Multiple SLC Transporters.
Benoît Chevalier, Nesrine Baatallah, Matthieu Najm, Solène Castanier, Vincent Jung

Int J Mol Sci· August 2022

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Reclassifying inconclusive diagnosis after newborn screening for cystic fibrosis. Moving forward.
Aurelie Hatton, Anne Bergougnoux, Katarzyna Zybert, Benoit Chevalier, Myriam Mesbahi

J Cyst Fibros· May 2022

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Pharmacological chaperones improve intra-domain stability and inter-domain assembly via distinct binding sites to rescue misfolded CFTR.
Nesrine Baatallah, Ahmad Elbahnsi, Jean-Paul Mornon, Benoit Chevalier, Iwona Pranke

Cell Mol Life Sci· December 2021

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Author Correction: New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation.
Sara Bitam, Ahmad Elbahnsi, Geordie Creste, Iwona Pranke, Benoit Chevalier

Sci Rep· September 2021

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Exon identity influences splicing induced by exonic variants and in silico prediction efficacy.
Natacha Martin, Anne Bergougnoux, Nesrine Baatallah, Benoit Chevalier, Jessica Varilh

J Cyst Fibros· May 2021

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Modulators of CFTR. Updates on clinical development and future directions.
Emmanuelle Bardin, Alexandra Pastor, Michaela Semeraro, Anita Golec, Kate Hayes, Benoit Chevalier

Eur J Med Chem· March 2021

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New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation.
Sara Bitam, Ahmad Elbahnsi, Geordie Creste, Iwona Pranke, Benoit Chevalier

Sci Rep· March 2021

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The influence of CFTR complex alleles on precision therapy of cystic fibrosis.
Benoit Chevalier, Alexandre Hinzpeter

J Cyst Fibros· March 2020

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Targeting different binding sites in the CFTR structures allows to synergistically potentiate channel activity.
Lionel Froux, Ahmad Elbahnsi, Benjamin Boucherle, Arnaud Billet, Nesrine Baatallah, Benoit Chevalier

Eur J Med Chem· March 2020

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The "one airway, one disease" concept in light of Th2 inflammation.
Lisa Giovannini-Chami, Agnès Paquet, Céline Sanfiorenzo, Nicolas Pons, Julie Cazareth, Benoit Chevalier

Eur Respir J· October 2018

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