Publications by authors named "Benoit Gourdet"

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A Flexible End-to-End Automated Sample Preparation Workflow Enables Standardized and Scalable Bottom-up Proteomics.
Sandra Schär, Luca Räss, Liliana Malinovska, Simonas Savickas, Francesca Cavallo, Benoit Gourdet

Anal Chem· October 2025

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To homeostasis and beyond! Recent advances in the medicinal chemistry of heterobifunctional derivatives.
Diana Castagna, Benoit Gourdet, Roland Hjerpe, Philip MacFaul, Andrew Novak

Prog Med Chem· October 2024

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Identification of the Clinical Candidate (R)-(1-(4-Fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist.
Hazel J Hunt, Joseph K Belanoff, Iain Walters, Benoit Gourdet, Jennifer Thomas

J Med Chem· April 2017

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1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as potent GR antagonists with reduced hERG inhibition and an improved pharmacokinetic profile.
Hazel J Hunt, Joseph K Belanoff, Emily Golding, Benoit Gourdet, Timothy Phillips

Bioorg Med Chem Lett· December 2015

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Catalytic asymmetric dihydroxylation of enamides and application to the total synthesis of (+)-tanikolide.
Benoit Gourdet, Hon Wai Lam

Angew Chem Int Ed Engl· November 2010

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Rhodium-catalyzed annulation of ynamides with bifunctional arylboron reagents.
Benoit Gourdet, Mairi E Rudkin, Hon Wai Lam

Org Lett· June 2010

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Preparation of multisubstituted enamides via rhodium-catalyzed carbozincation and hydrozincation of ynamides.
Benoit Gourdet, Mairi E Rudkin, Ciorsdaidh A Watts, Hon Wai Lam

J Org Chem· October 2009

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Stereoselective synthesis of multisubstituted enamides via rhodium-catalyzed carbozincation of ynamides.
Benoit Gourdet, Hon Wai Lam

J Am Chem Soc· March 2009

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