Publications by authors named "Roland Hjerpe"

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A Flexible End-to-End Automated Sample Preparation Workflow Enables Standardized and Scalable Bottom-up Proteomics.
Sandra Schär, Luca Räss, Liliana Malinovska, Simonas Savickas, Francesca Cavallo, Roland Hjerpe

Anal Chem· October 2025

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To homeostasis and beyond! Recent advances in the medicinal chemistry of heterobifunctional derivatives.
Diana Castagna, Benoit Gourdet, Roland Hjerpe, Philip MacFaul, Andrew Novak

Prog Med Chem· October 2024

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Breaking Bad Proteins-Discovery Approaches and the Road to Clinic for Degraders.
Corentin Bouvier, Rachel Lawrence, Francesca Cavallo, Wendy Xolalpa, Allan Jordan, Roland Hjerpe

Cells· March 2024

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Cryo-EM reveals important regulatory mechanism of the workhorses of targeted protein degradation.
Roland Hjerpe, Thimo Kurz

Mol Cell· July 2023

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U1A is a positive regulator of the expression of heterologous and cellular genes involved in cell proliferation and migration.
Eric Rovira, Beatriz Moreno, Nerea Razquin, Roland Hjerpe, Monika Gonzalez-Lopez

Mol Ther Nucleic Acids· June 2022

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Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death.
Matthew J Keuss, Roland Hjerpe, Oliver Hsia, Robert Gourlay, Richard Burchmore

EMBO J· March 2019

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UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.
Roland Hjerpe, John S Bett, Matthew J Keuss, Alexandra Solovyova, Thomas G McWilliams

Cell· August 2016

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Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity.
Valérie Lang, Chiara Pallara, Amaia Zabala, Sofia Lobato-Gil, Fernando Lopitz-Otsoa, Roland Hjerpe

Mol Oncol· July 2014

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Heterologous SUMO-2/3-ubiquitin chains optimize IκBα degradation and NF-κB activity.
Fabienne Aillet, Fernando Lopitz-Otsoa, Isabel Egaña, Roland Hjerpe, Paul Fraser

PLoS One· June 2013

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NEDD8 overexpression results in neddylation of ubiquitin substrates by the ubiquitin pathway.
Roland Hjerpe, Yann Thomas, Thimo Kurz

J Mol Biol· August 2012

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Isolation of ubiquitylated proteins using tandem ubiquitin-binding entities.
Fabienne Aillet, Fernando Lopitz-Otsoa, Roland Hjerpe, Mónica Torres-Ramos, Valérie Lang

Methods Mol Biol· July 2012

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Changes in the ratio of free NEDD8 to ubiquitin triggers NEDDylation by ubiquitin enzymes.
Roland Hjerpe, Yann Thomas, Jesse Chen, Aleksandra Zemla, Siobhan Curran

Biochem J· February 2012

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Sumoylation modulates the activity of Spalt-like proteins during wing development in Drosophila.
Jonatan Sánchez, Ana Talamillo, Fernando Lopitz-Otsoa, Coralia Pérez, Roland Hjerpe

J Biol Chem· August 2010

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Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation.
Roland Hjerpe, Fabienne Aillet, Fernando Lopitz-Otsoa, Valerie Lang, Mónica Torres-Ramos

Int J Biochem Cell Biol· May 2010

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SUMO and ubiquitin modifications during steroid hormone synthesis and function.
Ana Talamillo, David Martín, Roland Hjerpe, Jonatan Sánchez, Rosa Barrio

Biochem Soc Trans· February 2010

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Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities.
Roland Hjerpe, Fabienne Aillet, Fernando Lopitz-Otsoa, Valerie Lang, Patrick England

EMBO Rep· November 2009

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Efficient approaches for characterizing ubiquitinated proteins.
Roland Hjerpe, Manuel S Rodríguez

Biochem Soc Trans· October 2008

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Alternative UPS drug targets upstream the 26S proteasome.
Roland Hjerpe, Manuel S Rodríguez

Int J Biochem Cell Biol· August 2008

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