Publications by authors named "Benoit Joseph"

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Identifying Potent Nonsense-Mediated mRNA Decay Inhibitors with a Novel Screening System.
Julie Carrard, Fiona Ratajczak, Joséphine Elsens, Catherine Leroy, Rebekah Kong, Benoît Joseph

Biomedicines· October 2023

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Monomethyl Auristatin E Grafted-Liposomes to Target Prostate Tumor Cell Lines.
Ariana Abawi, Xiaoyi Wang, Julien Bompard, Anna Bérot, Valentina Andretto, Benoit Joseph

Int J Mol Sci· April 2021

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Exatecan Antibody Drug Conjugates Based on a Hydrophilic Polysarcosine Drug-Linker Platform.
Louise Conilh, Guy Fournet, Eric Fourmaux, Angélique Murcia, Eva-Laure Matera, Benoît Joseph

Pharmaceuticals (Basel)· March 2021

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Monodisperse polysarcosine-based highly-loaded antibody-drug conjugates.
Warren Viricel, Guy Fournet, Sabine Beaumel, Emeline Perrial, Sébastien Papot, Benoît Joseph

Chem Sci· April 2019

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Room-Temperature and Transition-Metal-Free Intramolecular α-Arylation of Ketones: A Mild Access to Tetracyclic Indoles and 7-Azaindoles.
Chérif Adouama, María E Budén, Walter D Guerra, Marcelo Puiatti, Benoît Joseph

Org Lett· January 2019

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Correction: Characterization of Transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis.
Navina L Chrobok, John G J M Bol, Cornelis A Jongenelen, John J P Brevé, Said El Alaoui, Benoît Joseph

PLoS One· December 2018

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Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.
Amparo Garcia-Lopez, Francesca Tessaro, Hendrik R A Jonker, Anna Wacker, Christian Richter, Benoît Joseph

Nat Commun· May 2018

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Targeting Integrin-Dependent Adhesion and Signaling with 3-Arylquinoline and 3-Aryl-2-Quinolone Derivatives: A new Class of Integrin Antagonists.
Sandrine Fiorucci, Xiaochen Lin, Karin Sadoul, Guy Fournet, Daniel Bouvard, Benoît Joseph

PLoS One· June 2016

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Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis.
Marie Jarry, Céline Lecointre, Céline Malleval, Laurence Desrues, Marie-Thérèse Schouft, Benoît Joseph

Neuro Oncol· November 2014

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Synthesis and biological evaluation of tetrahydro[1,4]diazepino[1,2-a]indol-1-ones as cyclin-dependent kinase inhibitors.
Aurélien Putey, Guy Fournet, Olivier Lozach, Lionel Perrin, Laurent Meijer, Benoît Joseph

Eur J Med Chem· August 2014

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New 1-arylindoles based serotonin 5-HT7 antagonists. Synthesis and binding evaluation studies.
Charlène Sagnes, Guy Fournet, Grzegorz Satala, Andrzej J Bojarski, Benoît Joseph

Eur J Med Chem· March 2014

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Use of ATP analogs to inhibit HIV-1 transcription.
Aarthi Narayanan, Gavin Sampey, Rachel Van Duyne, Irene Guendel, Kylene Kehn-Hall, Benoît Joseph

Virology· October 2012

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Targeting low molecular weight cyclin E (LMW-E) in breast cancer.
Angela Nanos-Webb, Natalie A Jabbour, Asha S Multani, Hannah Wingate, Nassima Oumata, Benoît Joseph

Breast Cancer Res Treat· April 2012

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Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives.
Daniel B Nichols, Guy Fournet, K R Gurukumar, Amartya Basu, Jin-Ching Lee, Benoît Joseph

Eur J Med Chem· March 2012

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Unexpected matrix interactions in liquid secondary ion mass spectrometry of two pyranosyl mercaptans.
Christian Gardrat, Benoît Joseph, Christiane Vitry, Alain Castellan, Patrick Rollin

Rapid Commun Mass Spectrom· May 2011

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Structure-activity relationship and multidrug resistance study of new S-trityl-L-cysteine derivatives as inhibitors of Eg5.
Hung Yi Kristal Kaan, Johanna Weiss, Dominik Menger, Venkatasubramanian Ulaganathan, Katarzyna Tkocz, Benoît Joseph

J Med Chem· March 2011

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New insights into homopiperazine-based 5-HT1A/5-HT7R ligands: synthesis and biological evaluation.
Eduard Badarau, Aurélien Putey, Franck Suzenet, Benoit Joseph, Andrzej Bojarski

J Enzyme Inhib Med Chem· June 2010

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Indolobenzazepin-7-ones and 6-, 8-, and 9-membered ring derivatives as tubulin polymerization inhibitors: synthesis and structure--activity relationship studies.
Aurélien Putey, Florence Popowycz, Quoc-Tuan Do, Philippe Bernard, Sandeep K Talapatra, Benoît Joseph

J Med Chem· October 2009

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Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives.
Florence Popowycz, Cédric Schneider, Salvatore Debonis, Dimitrios A Skoufias, Frank Kozielski, Benoît Joseph

Bioorg Med Chem· May 2009

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Pyrazolo[1,5-a]-1,3,5-triazine as a purine bioisostere: access to potent cyclin-dependent kinase inhibitor (R)-roscovitine analogue.
Florence Popowycz, Guy Fournet, Cédric Schneider, Karima Bettayeb, Yoan Ferandin, Benoît Joseph

J Med Chem· February 2009

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Myosin phosphorylation triggers actin polymerization in vascular smooth muscle.
Xuesong Chen, Kristin Pavlish, Joseph N Benoit

Am J Physiol Heart Circ Physiol· November 2008

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N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine.
Karima Bettayeb, Hatem Sallam, Yoan Ferandin, Florence Popowycz, Guy Fournet, Benoît Joseph

Mol Cancer Ther· September 2008

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Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.
Salvatore Debonis, Dimitrios A Skoufias, Rose-Laure Indorato, François Liger, Bernard Marquet, Benoît Joseph

J Med Chem· March 2008

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Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex.
Aude Echalier, Karima Bettayeb, Yoan Ferandin, Olivier Lozach, Monique Clément, Benoît Joseph

J Med Chem· February 2008

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