Publications by authors named "Bernd Laber"

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The herbicidal natural product phosphonothrixin is an inhibitor of the riboflavin biosynthetic enzyme L-3,4-dihydroxy-2-butanone-4-phosphate synthase.
Bernd Laber, Yoann Huet, Jörg Freigang, Hansjörg Dietrich, Wolfgang Schulte

Pest Manag Sci· August 2025

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Aminoisothiazolamides, a new class of potent inhibitors of lysyl-tRNA synthetase.
David Bernier, David M Barber, Guido Bojack, Birgit Bollenbach-Wahl, Luke Churchman, Bernd Laber

Pest Manag Sci· July 2025

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Discovery and optimization of spirocyclic lactams that inhibit acyl-ACP thioesterase.
Elisabeth Asmus, David M Barber, Guido Bojack, Birgit Bollenbach-Wahl, Ronald W Brown, Bernd Laber

Pest Manag Sci· May 2025

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Synthesis and biological profile of substituted hexahydrofuro[3,4-b]furans, a novel class of bicyclic acyl-acyl carrier protein (ACP) thioesterase inhibitors.
Hartmut Ahrens, David M Barber, Guido Bojack, Birgit Bollenbach-Wahl, Luke Churchman, Bernd Laber

Pest Manag Sci· May 2025

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Scaffold hopping approaches for the exploration of herbicidally active compounds inhibiting Acyl-ACP Thioesterase.
Tyler Fahrenhorst-Jones, Stephanie Lee, Birgit Bollenbach-Wahl, Guido Bojack, Ralf Braun, Bernd Laber

Pest Manag Sci· May 2025

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The novel herbicide icafolin-methyl is a plant-specific inhibitor of tubulin polymerization.
Klaus-Bernhard Haaf, Olaf Peters, Bernd Laber, Gudrun Lange, Elmar Gatzweiler

Pest Manag Sci· May 2025

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Investigation of acetyl-CoA carboxylase-inhibiting herbicides that exhibit soybean crop selectivity.
Stephanie Lee, China Payne, Shaun Rees, Hartmut Ahrens, Lars Arve, Bernd Laber

Pest Manag Sci· May 2025

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Synthesis and biological profile of 2,3-dihydro[1,3]thiazolo[4,5-]pyridines, a novel class of acyl-ACP thioesterase inhibitors.
Jens Frackenpohl, David M Barber, Guido Bojack, Birgit Bollenbach-Wahl, Ralf Braun, Bernd Laber

Beilstein J Org Chem· March 2024

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A Study in Scaffold Hopping: Discovery and Optimization of Thiazolopyridines as Potent Herbicides That Inhibit Acyl-ACP Thioesterase.
Steven A G Abel, Neanne Alnafta, Elisabeth Asmus, Birgit Bollenbach-Wahl, Ralf Braun, Bernd Laber

J Agric Food Chem· November 2023

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Investigations into Simplified Analogues of the Herbicidal Natural Product (+)-Cornexistin.
Christian Steinborn, Aldo Tancredi, Christoph Habiger, Christina Diederich, Jan Kramer, Bernd Laber

Chemistry· July 2023

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First crystal structures of 1-deoxy-D-xylulose 5-phosphate synthase (DXPS) from Mycobacterium tuberculosis indicate a distinct mechanism of intermediate stabilization.
Robin M Gierse, Rick Oerlemans, Eswar R Reddem, Victor O Gawriljuk, Alaa Alhayek, Bernd Laber

Sci Rep· May 2022

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Photochemical transformation of a cellulose biosynthesis inhibitor into phytoene desaturase inhibitors.
Matthew C L Wakeham, Zelong Lim, Stephen D Lindell, Bernd Laber, Rüdiger Hain

Bioorg Med Chem Lett· October 2021

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Mechanism and structure based design of inhibitors of AMP and adenosine deaminase.
Stephen D Lindell, Simon Maechling, Robert Klein, Jörg Freigang, Bernd Laber

Bioorg Med Chem· August 2021

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Identification of a 1-deoxy-D-xylulose-5-phosphate synthase (DXS) mutant with improved crystallographic properties.
Robin M Gierse, Eswar R Reddem, Alaa Alhayek, Dominik Baitinger, Zhoor Hamid, Bernd Laber

Biochem Biophys Res Commun· February 2021

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Aclonifen targets solanesyl diphosphate synthase, representing a novel mode of action for herbicides.
Sabine Kahlau, Florian Schröder, Jörg Freigang, Bernd Laber, Gudrun Lange

Pest Manag Sci· October 2020

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Herbicides as weed control agents: state of the art: I. Weed control research and safener technology: the path to modern agriculture.
Hansjoerg Kraehmer, Bernd Laber, Chris Rosinger, Arno Schulz

Plant Physiol· November 2014

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Adenine nucleotide pool perturbation is a metabolic trigger for AMP deaminase inhibitor-based herbicide toxicity.
Richard L Sabina, Anna-Lisa Paul, Robert J Ferl, Bernd Laber, Stephen D Lindell

Plant Physiol· April 2007

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Determinants of enzymatic specificity in the Cys-Met-metabolism PLP-dependent enzymes family: crystal structure of cystathionine gamma-lyase from yeast and intrafamiliar structure comparison.
Albrecht Messerschmidt, Michael Worbs, Clemens Steegborn, Markus C Wahl, Robert Huber, Bernd Laber

Biol Chem· March 2003

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Enzyme-ligand complexes of pyridoxine 5'-phosphate synthase: implications for substrate binding and catalysis.
Marta Garrido-Franco, Bernd Laber, Robert Huber, Tim Clausen

J Mol Biol· August 2002

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Structure and function of threonine synthase from yeast.
Marta Garrido-Franco, Stephan Ehlert, Albrecht Messerschmidt, Snezan Marinkovic', Robert Huber, Bernd Laber

J Biol Chem· April 2002

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