Publications by authors named "Beth Apsel"

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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
Morris E Feldman, Beth Apsel, Aino Uotila, Robbie Loewith, Zachary A Knight

PLoS Biol· February 2009

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Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases.
Beth Apsel, Jimmy A Blair, Beatriz Gonzalez, Tamim M Nazif, Morri E Feldman

Nat Chem Biol· November 2008

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Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha.
Eli R Zunder, Zachary A Knight, Benjamin T Houseman, Beth Apsel, Kevan M Shokat

Cancer Cell· August 2008

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Discovery of trypanocidal compounds by whole cell HTS of Trypanosoma brucei.
Zachary B Mackey, Arthur M Baca, Jeremy P Mallari, Beth Apsel, Anang Shelat

Chem Biol Drug Des· May 2006

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Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA.
Michael H Pillinger, Victoria Dinsell, Beth Apsel, Sonia N Tolani, Nada Marjanovic

Br J Pharmacol· July 2004

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Cyclooxygenase-2-derived E prostaglandins down-regulate matrix metalloproteinase-1 expression in fibroblast-like synoviocytes via inhibition of extracellular signal-regulated kinase activation.
Michael H Pillinger, Pamela B Rosenthal, Sonia N Tolani, Beth Apsel, Victoria Dinsell

J Immunol· December 2003

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