Publications by authors named "Bethany Mattson"

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Discovery of Gut-Restricted PRMT5 Inhibitors to Intercept Colorectal Cancer in Patients with Genetic Loss of Tumor Suppressor Adenomatous Polyposis Coli.
Fabian Hulpia, Wim Schepens, Susan Lepri, Johan Nicolaï, Zhengyu Jiang, Bethany Mattson

J Med Chem· November 2025

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Discovery and pharmacological characterization of cetrelimab (JNJ-63723283), an anti-programmed cell death protein-1 (PD-1) antibody, in human cancer models.
Nikki DeAngelis, Catherine Ferrante, Gordon Powers, Jocelyn Sendecki, Bethany Mattson

Cancer Chemother Pharmacol· April 2022

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A novel C2 domain binding CD33xCD3 bispecific antibody with potent T-cell redirection activity against acute myeloid leukemia.
Priyanka Nair-Gupta, Michael Diem, Dara Reeves, Weirong Wang, Robert Schulingkamp, Bethany Mattson

Blood Adv· March 2020

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Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies.
Hui-Ling Wang, Kristin L Andrews, Shon K Booker, Jude Canon, Victor J Cee, Bethany Mattson

J Med Chem· February 2019

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Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors.
Liping H Pettus, Kristin L Andrews, Shon K Booker, Jie Chen, Victor J Cee, Bethany Mattson

J Med Chem· July 2016

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Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.
Victor J Cee, Frank Chavez, Bradley Herberich, Brian A Lanman, Liping H Pettus, Bethany K Mattson

ACS Med Chem Lett· April 2016

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Identification of a novel recepteur d'origine nantais/c-met small-molecule kinase inhibitor with antitumor activity in vivo.
Yihong Zhang, Paula J Kaplan-Lefko, Karen Rex, Yajing Yang, Jodi Moriguchi, Bethany Mattson

Cancer Res· August 2008

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