Publications by authors named "Bikash Debnath"

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Recent Advances in Multifaceted Drug Delivery Using Natural Polysaccharides and Polyacrylamide-based Nanomaterials in Nanoformulation.
Paromita Dutta Choudhury, Abu Md Ashif Ikbal, Sourav Saha, Rabin Debnath, Bikash Debnath

Curr Top Med Chem· April 2025

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PSP205, a Novel Phenyl Sulfonyl Piperidine, Induces Apoptotic Cell Death in Colon Cancer by Modulating Coat Protein Complex-Mediated Vesicle Trafficking.
Soma Samanta, Joyeeta Roy, Bikash Debnath, Mats Ljungman, Nouri Neamati

ACS Pharmacol Transl Sci· April 2025

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Novel design of cryptographic architecture of nanorouter using quantum-dot cellular automata nanotechnology.
Sankit Kassa, Jadav Chandra Das, Vijay Lamba, Debashis De, Bikash Debnath

Sci Rep· May 2024

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Pyrazolone derivatives as potent and selective small-molecule SIRT5 inhibitors.
Jian Yao, Yudong Yin, Hong Han, Shaoting Chen, Yuxiang Zheng, Bikash Debnath

Eur J Med Chem· February 2023

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Identification of 2-hydroxybenzoic acid derivatives as selective SIRT5 inhibitors.
Yanghan Liu, Bikash Debnath, Surinder Kumar, David B Lombard, Nouri Neamati

Eur J Med Chem· November 2022

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The Hydroxyquinoline Analogue YUM70 Inhibits GRP78 to Induce ER Stress-Mediated Apoptosis in Pancreatic Cancer.
Soma Samanta, Suhui Yang, Bikash Debnath, Ding Xue, Yuting Kuang

Cancer Res· April 2021

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Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy.
Brandt C Huddle, Edward Grimley, Mikhail Chtcherbinine, Cameron D Buchman, Cyrus Takahashi, Bikash Debnath

Eur J Med Chem· February 2021

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Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.
Brandt C Huddle, Edward Grimley, Cameron D Buchman, Mikhail Chtcherbinine, Bikash Debnath

J Med Chem· October 2018

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Synthesis, Structure-Activity Relationship Studies, and ADMET Properties of 3-Aminocyclohex-2-en-1-ones as Chemokine Receptor 2 (CXCR2) Antagonists.
Weiyang Dai, Wenmin Chen, Bikash Debnath, Yong Wu, Nouri Neamati

ChemMedChem· May 2018

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Role of the CXCL8-CXCR1/2 Axis in Cancer and Inflammatory Diseases.
Helen Ha, Bikash Debnath, Nouri Neamati

Theranostics· February 2018

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Synthesis, ADMET Properties, and Biological Evaluation of Benzothiazole Compounds Targeting Chemokine Receptor 2 (CXCR2).
Wesam E Mehanna, Tiangong Lu, Bikash Debnath, Deena S Lasheen, Rabah A T Serya

ChemMedChem· July 2017

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Discovery of novel 3-hydroxypicolinamides as selective inhibitors of HIV-1 integrase-LEDGF/p75 interaction.
Feng-Hua Zhang, Bikash Debnath, Zhong-Liang Xu, Liu-Meng Yang, Li-Rui Song

Eur J Med Chem· January 2017

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Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor.
Kavya Ramkumar, Soma Samanta, Anahita Kyani, Suhui Yang, Shuzo Tamura, Bikash Debnath

Nat Commun· October 2016

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Discovery of Novel CXCR2 Inhibitors Using Ligand-Based Pharmacophore Models.
Helen Ha, Bikash Debnath, Srinivas Odde, Tim Bensman, Henry Ho

J Chem Inf Model· August 2015

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Design and discovery of 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide inhibitors of HIV-1 integrase.
Daoguang Zhang, Bikash Debnath, Shenghui Yu, Tino Wilson Sanchez, Frauke Christ

Bioorg Med Chem· October 2014

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Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction.
Erik Serrao, Zhong-Liang Xu, Bikash Debnath, Frauke Christ, Zeger Debyser

Bioorg Med Chem· October 2013

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Small molecule inhibitors of CXCR4.
Bikash Debnath, Shili Xu, Fedora Grande, Antonio Garofalo, Nouri Neamati

Theranostics· September 2013

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Stabilization of MDA-7/IL-24 for colon cancer therapy.
Shili Xu, Takashi Oshima, Toshio Imada, Munetaka Masuda, Bikash Debnath

Cancer Lett· July 2013

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Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.
Erik Serrao, Bikash Debnath, Hiroyuki Otake, Yuting Kuang, Frauke Christ

J Med Chem· March 2013

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Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions.
Tino Wilson Sanchez, Bikash Debnath, Frauke Christ, Hiroyuki Otake, Zeger Debyser

Bioorg Med Chem· February 2013

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Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties.
Li-Fan Zeng, Yong Wang, Roza Kazemi, Shili Xu, Zhong-Liang Xu, Bikash Debnath

J Med Chem· November 2012

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Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment.
Shili Xu, Alexey N Butkevich, Roppei Yamada, Yu Zhou, Bikash Debnath

Proc Natl Acad Sci U S A· October 2012

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Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.
Bikash Debnath, Shili Xu, Nouri Neamati

J Med Chem· August 2012

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Design of HIV-1 integrase inhibitors targeting the catalytic domain as well as its interaction with LEDGF/p75: a scaffold hopping approach using salicylate and catechol groups.
Xing Fan, Feng-Hua Zhang, Rasha I Al-Safi, Li-Fan Zeng, Yumna Shabaik, Bikash Debnath

Bioorg Med Chem· August 2011

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Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.
Stephanie M Stanford, Divya Krishnamurthy, Matthew D Falk, Rossella Messina, Bikash Debnath

J Med Chem· March 2011

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