Publications by authors named "Cameron D Buchman"

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Pan-H7 influenza human antibody virus neutralization depends on avidity and steric hindrance.
Iuliia M Gilchuk, Jinhui Dong, Ryan P Irving, Cameron D Buchman, Erica Armstrong

JCI Insight· July 2025

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Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation.
Monicah N Bwayi, Efren Garcia-Maldonado, Sergio C Chai, Boer Xie, Shirish Chodankar, Cameron D Buchman

Nucleic Acids Res· April 2022

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Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5.
Jingheng Wang, Cameron D Buchman, Jayaraman Seetharaman, Darcie J Miller, Andrew D Huber

J Am Chem Soc· November 2021

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Development of 2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one inhibitors of aldehyde dehydrogenase 1A (ALDH1A) as potential adjuncts to ovarian cancer chemotherapy.
Brandt C Huddle, Edward Grimley, Mikhail Chtcherbinine, Cameron D Buchman, Cyrus Takahashi

Eur J Med Chem· February 2021

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Mutation of a single amino acid of pregnane X receptor switches an antagonist to agonist by altering AF-2 helix positioning.
Andrew D Huber, William C Wright, Wenwei Lin, Kinjal Majumder, Jonathan A Low, Cameron D Buchman

Cell Mol Life Sci· January 2021

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Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.
Brandt C Huddle, Edward Grimley, Cameron D Buchman, Mikhail Chtcherbinine, Bikash Debnath

J Med Chem· October 2018

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A current structural perspective on PXR and CAR in drug metabolism.
Cameron D Buchman, Sergio C Chai, Taosheng Chen

Expert Opin Drug Metab Toxicol· June 2018

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Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives.
Cameron D Buchman, Thomas D Hurley

J Med Chem· March 2017

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N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes.
Cynthia A Morgan, Bibek Parajuli, Cameron D Buchman, Karl Dria, Thomas D Hurley

Chem Biol Interact· June 2015

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Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.
Cameron D Buchman, Krishna K Mahalingan, Thomas D Hurley

Chem Biol Interact· June 2015

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Enrichment of chemical libraries docked to protein conformational ensembles and application to aldehyde dehydrogenase 2.
Bo Wang, Cameron D Buchman, Liwei Li, Thomas D Hurley, Samy O Meroueh

J Chem Inf Model· July 2014

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