Publications by authors named "Cynthia A Morgan"

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Discovery and Development of Small-Molecule Inhibitors of Glycogen Synthase.
Buyun Tang, Mykhaylo S Frasinyuk, Vimbai M Chikwana, Krishna K Mahalingan, Cynthia A Morgan

J Med Chem· April 2020

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A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.
Ilana Chefetz, Edward Grimley, Kun Yang, Linda Hong, Ekaterina V Vinogradova, Cynthia A Morgan, Meredith Morgan

Cell Rep· March 2019

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Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.
Brandt C Huddle, Edward Grimley, Cameron D Buchman, Mikhail Chtcherbinine, Bikash Debnath, Cynthia A Morgan

J Med Chem· October 2018

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Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
Cynthia A Morgan, Thomas D Hurley

Chem Biol Interact· June 2015

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N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes.
Cynthia A Morgan, Bibek Parajuli, Cameron D Buchman, Karl Dria, Thomas D Hurley

Chem Biol Interact· June 2015

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Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors.
Cynthia A Morgan, Thomas D Hurley

J Med Chem· February 2015

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The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octane-3-carboxamide (SCH 655842): comparison of efficacy and side effects across rodent species.
Sherry X Lu, Guy A Higgins, Robert A Hodgson, Lynn A Hyde, Robert A Del Vecchio, Cynthia A Morgan

Eur J Pharmacol· July 2011

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The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).
Geoffrey B Varty, Sherry X Lu, Cynthia A Morgan, Mary E Cohen-Williams, Robert A Hodgson

J Pharmacol Exp Ther· August 2008

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Cyclobutane derivatives as potent NK1 selective antagonists.
Michelle Laci Wrobleski, Gregory A Reichard, Sunil Paliwal, Sapna Shah, Hon-Chung Tsui, Cynthia A Morgan

Bioorg Med Chem Lett· July 2006

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Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions.
Ho-Jane Shue, Xiao Chen, John H Schwerdt, Sunil Paliwal, David J Blythin, Cynthia A Morgan

Bioorg Med Chem Lett· February 2006

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Cyclic urea derivatives as potent NK1 selective antagonists.
Ho-Jane Shue, Xiao Chen, Neng-Yang Shih, David J Blythin, Sunil Paliwal, Cynthia A Morgan

Bioorg Med Chem Lett· September 2005

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The gerbil elevated plus-maze I: behavioral characterization and pharmacological validation.
Geoffrey B Varty, Cynthia A Morgan, Mary E Cohen-Williams, Vicki L Coffin, Galen J Carey

Neuropsychopharmacology· September 2002

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The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists.
Geoffrey B Varty, Mary E Cohen-Williams, Cynthia A Morgan, Ursula Pylak, Ruth A Duffy

Neuropsychopharmacology· September 2002

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Correlation of neurokinin (NK) 1 receptor occupancy in gerbil striatum with behavioral effects of NK1 antagonists.
Ruth A Duffy, Geoffrey B Varty, Cynthia A Morgan, Jean E Lachowicz

J Pharmacol Exp Ther· May 2002

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