Publications by authors named "Ruth A Duffy"

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An Integrated Pharmacokinetic-Pharmacodynamic-Pharmacoeconomic Modeling Method to Evaluate Treatments for Adults with Schizophrenia.
Marjanne A Piena, Natalie Houwing, Carla W Kraan, Xiaofeng Wang, Heidi Waters, Ruth A Duffy

Pharmacoeconomics· January 2022

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Making Sense of the Matrix: A Qualitative Assessment and Commentary on Connecting Psychiatric Symptom Scale Items to the Research Domain Criteria (RDoC).
Leslie Citrome, Anissa Abi-Dargham, Robert M Bilder, Ruth A Duffy, Boadie W Dunlop

Innov Clin Neurosci· January 2022

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Real-World Treatment Patterns and Characteristics Among Patients with Agitation and Dementia in the United States: Findings from a Large, Observational, Retrospective Chart Review.
Myrlene Sanon Aigbogun, Martin Cloutier, Marjolaine Gauthier-Loiselle, Annie Guerin, Martin Ladouceur, Ruth A Duffy

J Alzheimers Dis· September 2021

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Cholesteryl ester transfer protein (CETP) inhibitors based on cyclic urea, bicyclic urea and bicyclic sulfamide cores.
Jian Liu, Patrick P Shao, Deodial Guiadeen, Arto Krikorian, Wanying Sun, Ruth A Duffy, Joseph L Duffy

Bioorg Med Chem Lett· January 2021

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Association of the US Food and Drug Administration Antipsychotic Drug Boxed Warning With Medication Use and Health Outcomes in Elderly Patients With Dementia.
Annalisa Rubino, Myrlene Sanon, Michael L Ganz, Alex Simpson, Miriam C Fenton, Ruth A Duffy

JAMA Netw Open· April 2020

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Successful switching of patients with acute schizophrenia from another antipsychotic to brexpiprazole: comparison of clinicians' choice of cross-titration schedules in a post hoc analysis of a randomized, double-blind, maintenance treatment study.
Christoph U Correll, Lily Shi, Catherine Weiss, Mary Hobart, Anna Eramo, Ruth A Duffy

CNS Spectr· October 2019

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Agitation in patients with dementia: a systematic review of epidemiology and association with severity and course.
Milena Anatchkova, Anne Brooks, Laura Swett, Ann Hartry, Ruth A Duffy

Int Psychogeriatr· September 2019

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The effects of brexpiprazole and aripiprazole on body weight as monotherapy in patients with schizophrenia and as adjunctive treatment in patients with major depressive disorder: an analysis of short-term and long-term studies.
Catherine Weiss, Emmanuelle Weiller, Ross A Baker, Ruth A Duffy, Keva K Gwin

Int Clin Psychopharmacol· September 2018

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The Role of Norepinephrine and Its α-Adrenergic Receptors in the Pathophysiology and Treatment of Major Depressive Disorder and Schizophrenia: A Systematic Review.
Vladimir Maletic, Anna Eramo, Keva Gwin, Steve J Offord, Ruth A Duffy

Front Psychiatry· March 2017

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Hospital Readmission Rates Among Patients With Schizophrenia Treated With Long-Acting Injectables or Oral Antipsychotics.
Joanna P MacEwan, Siddhesh A Kamat, Ruth A Duffy, Seth Seabury, Jacquelyn W Chou

Psychiatr Serv· November 2016

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Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach.
Jonathan E Wilson, Ravi Kurukulasuriya, Mikhail Reibarkh, Maud Reiter, Aaron Zwicker, Ruth A Duffy, Joseph L Duffy

ACS Med Chem Lett· March 2016

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Long-term outcomes of antipsychotic treatment in patients with first-episode schizophrenia: a systematic review.
Craig Karson, Ruth A Duffy, Anna Eramo, Anna-Greta Nylander, Steve J Offord

Neuropsychiatr Dis Treat· January 2016

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Rolapitant (SCH 619734): a potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets.
Ruth A Duffy, Cynthia Morgan, Robert Naylor, Guy A Higgins, Geoffrey B Varty

Pharmacol Biochem Behav· July 2012

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Diaryl piperidines as CB1 receptor antagonists.
Jack D Scott, Sarah W Li, Hongwu Wang, Yan Xia, Charles L Jayne, Ruth A Duffy

Bioorg Med Chem Lett· February 2010

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Discovery of a novel, potent and orally active series of gamma-lactams as selective NK1 antagonists.
Sunil Paliwal, Gregory A Reichard, Sapna Shah, Michelle Laci Wrobleski, Cheng Wang, Ruth A Duffy

Bioorg Med Chem Lett· July 2008

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Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model.
Hongwu Wang, Ruth A Duffy, George C Boykow, Samuel Chackalamannil, Vincent S Madison

J Med Chem· April 2008

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Cyclobutane derivatives as potent NK1 selective antagonists.
Michelle Laci Wrobleski, Gregory A Reichard, Sunil Paliwal, Sapna Shah, Hon-Chung Tsui, Ruth A Duffy

Bioorg Med Chem Lett· July 2006

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Cyclic urea derivatives as potent NK1 selective antagonists. Part II: Effects of fluoro and benzylic methyl substitutions.
Ho-Jane Shue, Xiao Chen, John H Schwerdt, Sunil Paliwal, David J Blythin, Ruth A Duffy

Bioorg Med Chem Lett· February 2006

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Cyclic urea derivatives as potent NK1 selective antagonists.
Ho-Jane Shue, Xiao Chen, Neng-Yang Shih, David J Blythin, Sunil Paliwal, Ruth A Duffy

Bioorg Med Chem Lett· September 2005

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Potential therapeutic targets for neurokinin-1 receptor antagonists.
Ruth A Duffy

Expert Opin Emerg Drugs· May 2004

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Isopropyl amide derivatives of potent and selective muscarinic M2 receptor antagonists.
Anandan Palani, Sundeep Dugar, John W Clader, William J Greenlee, Vilma Ruperto, Ruth A Duffy

Bioorg Med Chem Lett· April 2004

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Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity.
John W Clader, William Billard, Herbert Binch, Lian-Yong Chen, Gordon Crosby, Ruth A Duffy

Bioorg Med Chem· January 2004

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Enhancement of pharmacokinetic properties and in vivo efficacy of benzylidene ketal M(2) muscarinic receptor antagonists via benzamide modification.
Craig D Boyle, Susan F Vice, Jennifer Campion, Samuel Chackalamannil, Claire M Lankin, Ruth A Duffy

Bioorg Med Chem Lett· December 2002

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Improving the oral efficacy of CNS drug candidates: discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists.
Yuguang Wang, Samuel Chackalamannil, Zhiyong Hu, William J Greenlee, John Clader, Ruth A Duffy

J Med Chem· December 2002

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The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists.
Geoffrey B Varty, Mary E Cohen-Williams, Cynthia A Morgan, Ursula Pylak, Ruth A Duffy

Neuropsychopharmacology· September 2002

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