Publications by authors named "Binukumar B K"

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Genetic Landscape of Dystonia in Asian Indians.
Arti Saini, Inder Singh, Mukesh Kumar, Divya Madathiparambil Radhakrishnan, Ayush Agarwal

Mov Disord Clin Pract· May 2025

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Antiepileptic drugs carbamazepine and valproic acid mediate transcriptional activation of CYP1A1 via aryl hydrocarbon receptor and regulation of estrogen metabolism.
Neha Kanojia, Samiksha Kukal, Nitin Machahary, Shivangi Bora, Ankit Srivastava

J Steroid Biochem Mol Biol· April 2025

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The Genomic Landscape of Wilson Disease in a Pan India Disease Cohort and Population-Scale Data.
Mukesh Kumar, Srishti Sharma, Sanjay Pandey, Geetha Mammayil, Aslam Pala Kuzhiyil

Mov Disord Clin Pract· February 2025

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Generation of an induced pluripotent stem cell (iPSC) line (IGIBi026-A) derived from Wilson disease patient harboring compound heterozygous mutations [c.2165dupT (p.R723Efs31) and c.C813A (p.C271*)] in the ATP7B gene.
Bhaskar Jyoti Saikia, Juhi Bhardwaj, Arti Saini, Roopa Rajan, Binukumar B K

Stem Cell Res· December 2024

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TLX3 regulates CGN progenitor proliferation during cerebellum development and its dysfunction can lead to autism.
Surendran Parvathy, Budhaditya Basu, Suresh Surya, Rahul Jose, Vadakkath Meera

iScience· December 2024

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WilsonGenAI a deep learning approach to classify pathogenic variants in Wilson Disease.
Aastha Vatsyayan, Mukesh Kumar, Bhaskar Jyoti Saikia, Vinod Scaria, Binukumar B K

PLoS One· May 2024

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Cdk5-mediated oligodendrocyte myelin breakdown and neuroinflammation: Implications for the link between Type 2 Diabetes and Alzheimer's disease.
Sangita Paul, Juhi Bhardwaj, B K Binukumar

Biochim Biophys Acta Mol Basis Dis· February 2024

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Genetic epidemiology of autoinflammatory disease variants in Indian population from 1029 whole genomes.
Abhinav Jain, Rahul C Bhoyar, Kavita Pandhare, Anushree Mishra, Disha Sharma

J Genet Eng Biotechnol· December 2021

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Protocols for Characterization of Cdk5 Kinase Activity.
Anita Terse, Niranjana Amin, Bradford Hall, Manju Bhaskar, Binukumar B K

Curr Protoc· October 2021

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LncRNA VEAL2 regulates PRKCB2 to modulate endothelial permeability in diabetic retinopathy.
Paras Sehgal, Samatha Mathew, Ambily Sivadas, Arjun Ray, Jyoti Tanwar

EMBO J· August 2021

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Pharmacogenomic landscape of COVID-19 therapies from Indian population genomes.
S Sahana, Ambily Sivadas, Mohit Mangla, Abhinav Jain, Rahul C Bhoyar

Pharmacogenomics· July 2021

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Pallidal Deep Brain Stimulation for Related Dystonia in An Indian Patient.
Roopa Rajan, Kanwaljeet Garg, Arti Saini, Mukesh Kumar, B K Binukumar

Ann Indian Acad Neurol· March 2021

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IndiGenomes: a comprehensive resource of genetic variants from over 1000 Indian genomes.
Abhinav Jain, Rahul C Bhoyar, Kavita Pandhare, Anushree Mishra, Disha Sharma

Nucleic Acids Res· January 2021

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ATP7A Clinical Genetics Resource - A comprehensive clinically annotated database and resource for genetic variants in ATP7A gene.
Aditi Mhaske, K V Dileep, Mukesh Kumar, Mukta Poojary, Kavita Pandhare

Comput Struct Biotechnol J· September 2020

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Peripheral and orofacial pain sensation is unaffected by the loss of p39.
Michaela Prochazkova, Bradford Hall, Minghan Hu, Tracy Okine, Jennifer Reukauf

Mol Pain· September 2018

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Crosstalk Between the Unfolded Protein Response, MicroRNAs, and Insulin Signaling Pathways: In Search of Biomarkers for the Diagnosis and Treatment of Type 2 Diabetes.
Chinar Berry, Megha Lal, B K Binukumar

Front Endocrinol (Lausanne)· May 2018

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TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice.
Varsha Shukla, Jinsoo Seo, B K Binukumar, Niranjana D Amin, Preethi Reddy

J Alzheimers Dis· February 2018

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Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception.
Bradford E Hall, Michaela Prochazkova, Matthew R Sapio, Paul Minetos, Natalya Kurochkina

Sci Rep· January 2018

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Profiling of p5, a 24 Amino Acid Inhibitory Peptide Derived from the CDK5 Activator, p35 CDKR1 Against 70 Protein Kinases.
B K Binukumar, Steven L Pelech, Catherine Sutter, Varsha Shukla, Niranjana D Amin

J Alzheimers Dis· September 2016

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Analysis of the Inhibitory Elements in the p5 Peptide Fragment of the CDK5 Activator, p35, CDKR1 Protein.
B K Binukumar, Varsha Shukla, Niranjana D Amin, Manju Bhaskar, Suzanne Skuntz

J Alzheimers Dis· August 2016

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TFP5/TP5 peptide provides neuroprotection in the MPTP model of Parkinson's disease.
B K Binukumar, Harish C Pant

Neural Regen Res· May 2016

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Peptide TFP5/TP5 derived from Cdk5 activator P35 provides neuroprotection in the MPTP model of Parkinson's disease.
B K Binukumar, Varsha Shukla, Niranjana D Amin, Philip Grant, M Bhaskar

Mol Biol Cell· December 2015

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TFP5, a peptide derived from p35, a Cdk5 neuronal activator, rescues cortical neurons from glucose toxicity.
B K Binukumar, Ya-Li Zheng, Varsha Shukla, Niranjana D Amin, Philip Grant

J Alzheimers Dis· October 2014

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Topographic regulation of neuronal intermediate filaments by phosphorylation, role of peptidyl-prolyl isomerase 1: significance in neurodegeneration.
B K Binukumar, Varsha Shukla, Niranjana D Amin, Preethi Reddy, Suzanne Skuntz

Histochem Cell Biol· July 2013

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siRNA against presenilin 1 (PS1) down regulates amyloid β42 production in IMR-32 cells.
Ramesh J L Kandimalla, Willayat Yousuf Wani, B K Binukumar, Kiran Dip Gill

J Biomed Sci· January 2012

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