Publications by authors named "Biplab Dasgupta"

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Preclinical Evaluation of the Efficacy of a Cyclin-dependent Kinase Inhibitor Ribociclib in Combination with Letrozole Against Patient-Derived Glioblastoma Cells.
Sidharth N Gadgil, Aniruddha S Karve, Gary A Gudelsky, Bhavesh B Gabani, Mario Medvedovic, Biplab Dasgupta

Mol Cancer Ther· September 2025

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Integrative Multi-Omics Analysis Identifies Nuclear Factor I as a Key Driver of Dysregulated Purine Metabolism in DIPG.
Ian Mersich, Sunny Congrove, Matthew Horchar, Roman Caceres, Ranjithmenon Muraleedharan, Biplab Dasgupta

bioRxiv· May 2025

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Coordinated Targeting of S6K1/2 and AXL Disrupts Pyrimidine Biosynthesis in PTEN-Deficient Glioblastoma.
Catherine A Behrmann, Kelli N Ennis, Pranjal Sarma, Collin Wetzel, Nicholas A Clark, Biplab Dasgupta

Cancer Res Commun· August 2024

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A Multimodal Drug-Diet-Immunotherapy Combination Restrains Melanoma Progression and Metastasis.
Nicole Oatman, Mruniya V Gawali, Sunny Congrove, Román Cáceres, Abitha Sukumaran, Biplab Dasgupta

Cancer Res· July 2024

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A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas.
Pankaj B Desai, Aniruddha S Karve, Misam Zawit, Priyanka Arora, Nimita Dave, Biplab DasGupta

Clin Cancer Res· May 2024

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A Review of Approaches to Potentiate the Activity of Temozolomide against Glioblastoma to Overcome Resistance.
Aniruddha S Karve, Janki M Desai, Sidharth N Gadgil, Nimita Dave, Trisha M Wise-Draper, Biplab DasGupta

Int J Mol Sci· March 2024

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Chronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cells.
Daniel Shiloh Malawsky, Taylor Dismuke, Hedi Liu, Ethan Castellino, Jay Brenman, Biplab Dasgupta

iScience· December 2023

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Brain pharmacokinetics and metabolism of the AMP-activated protein kinase selective inhibitor SBI-0206965, an investigational agent for the treatment of glioblastoma.
Janki M Desai, Aniruddha S Karve, Gary A Gudelsky, Mruniya V Gawali, William Seibel, Biplab DasGupta

Invest New Drugs· October 2022

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Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole.
Aniruddha S Karve, Janki M Desai, Nimita Dave, Trisha M Wise-Draper, Gary A Gudelsky, Biplab DasGupta

Cancer Chemother Pharmacol· October 2022

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AMPK in the brain: its roles in glucose and neural metabolism.
Ranjithmenon Muraleedharan, Biplab Dasgupta

FEBS J· April 2022

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Analysis of reactive astrogliosis in mouse brain using hybridization combined with immunohistochemistry.
Ranjithmenon Muraleedharan, Diana Nardini, Ronald Raymond Waclaw, Biplab Dasgupta

STAR Protoc· March 2021

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Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer.
Nicole Oatman, Nupur Dasgupta, Priyanka Arora, Kwangmin Choi, Mruniya V Gawali, Biplab Dasgupta

Sci Adv· February 2021

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Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma.
Karin Golan, Abhishek K Singh, Orit Kollet, Mayla Bertagna, Mark J Althoff, Biplab Dasgupta

Blood· December 2020

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AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival.
Ranjithmenon Muraleedharan, Mruniya V Gawali, Durgesh Tiwari, Abitha Sukumaran, Nicole Oatman, Biplab Dasgupta

Cell Rep· September 2020

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Insight on Transcriptional Regulation of the Energy Sensing AMPK and Biosynthetic mTOR Pathway Genes.
Abitha Sukumaran, Kwangmin Choi, Biplab Dasgupta

Front Cell Dev Biol· July 2020

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Compound C/Dorsomorphin: Its Use and Misuse as an AMPK Inhibitor.
Biplab Dasgupta, William Seibel

Methods Mol Biol· January 2019

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Plasma and brain pharmacokinetics of letrozole and drug interaction studies with temozolomide in NOD-scid gamma mice and sprague dawley rats.
Priyanka Arora, Courtney Huff Adams, Gary Gudelsky, Biplab DasGupta, Pankaj B Desai

Cancer Chemother Pharmacol· January 2019

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Author Correction: AMP kinase promotes glioblastoma bioenergetics and tumour growth.
Rishi Raj Chhipa, Qiang Fan, Jane Anderson, Ranjithmenon Muraleedharan, Yan Huang, Nupur Dasgupta, Biplab Dasgupta

Nat Cell Biol· November 2018

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Publisher Correction: AMP kinase promotes glioblastoma bioenergetics and tumour growth.
Rishi Raj Chhipa, Qiang Fan, Jane Anderson, Ranjithmenon Muraleedharan, Yan Huang, Nupur Dasgupta, Biplab Dasgupta

Nat Cell Biol· October 2018

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AMP kinase promotes glioblastoma bioenergetics and tumour growth.
Rishi Raj Chhipa, Qiang Fan, Jane Anderson, Ranjithmenon Muraleedharan, Yan Huang, Nupur Dasgupta, Biplab Dasgupta

Nat Cell Biol· July 2018

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Activation of the Receptor Tyrosine Kinase AXL Regulates the Immune Microenvironment in Glioblastoma.
Hirokazu Sadahiro, Kyung-Don Kang, Justin T Gibson, Mutsuko Minata, Hai Yu, Biplab DasGupta

Cancer Res· June 2018

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Copb2 is essential for embryogenesis and hypomorphic mutations cause human microcephaly.
Andrew DiStasio, Ashley Driver, Kristen Sund, Milene Donlin, Ranjith M Muraleedharan, Biplab Dasgupta

Hum Mol Genet· December 2017

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The transcription factor Olig2 is important for the biology of diffuse intrinsic pontine gliomas.
Jane L Anderson, Ranjithmenon Muraleedharan, Nicole Oatman, Amanda Klotter, Satarupa Sengupta, Biplab Dasgupta

Neuro Oncol· August 2017

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FOXD1-ALDH1A3 Signaling Is a Determinant for the Self-Renewal and Tumorigenicity of Mesenchymal Glioma Stem Cells.
Peng Cheng, Jia Wang, Indrayani Waghmare, Stefania Sartini, Vito Coviello, Biplab Dasgupta

Cancer Res· December 2016

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