Publications by authors named "Birgit Dreier"

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Selective targeting of TBXT with DARPins identifies regulatory networks and therapeutic vulnerabilities in chordoma.
Charles S Umbaugh, Marie Groth, Cihan Erkut, Kwang-Seok Lee, Joana Marinho, Birgit Dreier

Sci Adv· September 2025

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Heterodimerization of staphylococcal phage φ2638A endolysin isoforms and their functional role in bacterial lysis.
Léa V Zinsli, Anna M Sobieraj, Jiemin Du, Patrick Ernst, Susanne Meile, Birgit Dreier

Microlife· June 2025

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DARPin-induced reactivation of p53 in HPV-positive cells.
Philipp Münick, Alexander Strubel, Dimitrios-Ilias Balourdas, Julianne S Funk, Marco Mernberger, Birgit Dreier

Nat Struct Mol Biol· May 2025

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DARPins as a novel tool to detect and degrade p73.
Philipp Münick, Jasmin Zielinski, Alexander Strubel, Niklas Gutfreund, Birgit Dreier

Cell Death Dis· December 2024

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A designed ankyrin-repeat protein that targets Parkinson's disease-associated LRRK2.
Verena Dederer, Marta Sanz Murillo, Eva P Karasmanis, Kathryn S Hatch, Deep Chatterjee, Birgit Dreier

J Biol Chem· July 2024

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mRNA Display Pipeline for Protein Biosensor Construction.
Zhenling Cui, Cagla Ergun Ayva, Yi Jin Liew, Zhong Guo, Roxane Mutschler, Birgit Dreier

ACS Sens· June 2024

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Designed Ankyrin Repeat Proteins as Actin Labels of Distinct Cytoskeletal Structures in Living Cells.
Julia R Ivanova, Amelie S Benk, Jonas V Schaefer, Birgit Dreier, Leon O Hermann

ACS Nano· March 2024

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DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma.
Alexander Strubel, Philipp Münick, Oliver Hartmann, Apirat Chaikuad, Birgit Dreier

Cell Death Dis· October 2023

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Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Matthias Glögl, Nikolas Friedrich, Gabriele Cerutti, Thomas Lemmin, Young D Kwon, Birgit Dreier

Nat Struct Mol Biol· September 2023

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Assessing immunogenicity barriers of the HIV-1 envelope trimer.
Liridona Maliqi, Nikolas Friedrich, Matthias Glögl, Stefan Schmutz, Daniel Schmidt, Birgit Dreier

NPJ Vaccines· September 2023

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Designed ankyrin repeat proteins for detecting prostate-specific antigen expression .
Melanie Gut, Birgit Dreier, Sven Furler, Jens Sobek, Andreas Plückthun

RSC Chem Biol· July 2023

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Nuclear myosin VI maintains replication fork stability.
Jie Shi, Kristine Hauschulte, Ivan Mikicic, Srijana Maharjan, Valerie Arz, Birgit Dreier

Nat Commun· June 2023

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Designed Ankyrin Repeat Proteins provide insights into the structure and function of CagI and are potent inhibitors of CagA translocation by the Helicobacter pylori type IV secretion system.
Marine Blanc, Clara Lettl, Jérémy Guérin, Anaïs Vieille, Sven Furler, Birgit Dreier

PLoS Pathog· May 2023

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Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Alexander Strubel, Philipp Münick, Apirat Chaikuad, Birgit Dreier, Jonas Schaefer

Cell Death Differ· December 2022

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Structure of a hydrophobic leucinostatin derivative determined by host lattice display.
Cedric Kiss, Flavio M Gall, Birgit Dreier, Michael Adams, Rainer Riedl

Acta Crystallogr D Struct Biol· December 2022

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Sortase-Mediated Site-Specific Conjugation and Zr-Radiolabeling of Designed Ankyrin Repeat Proteins for PET.
Rachael Fay, Imre Törő, Anna-Lena Schinke, Branko Simic, Jonas V Schaefer, Birgit Dreier

Mol Pharm· October 2022

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A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology.
Benjamin F N Campbell, Antje Dittmann, Birgit Dreier, Andreas Plückthun, Shiva K Tyagarajan

Elife· October 2022

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Modular Adapters Utilizing Binders of Different Molecular Types Expand Cell-Targeting Options for Adenovirus Gene Delivery.
Patrick C Freitag, Fabian Brandl, Dominik Brücher, Fabian Weiss, Birgit Dreier

Bioconjug Chem· September 2022

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Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways.
Longlong Wang, Etori Aguiar Moreira, Georg Kempf, Yasuyuki Miyake, Blandina I Oliveira Esteves, Birgit Dreier

Cell Rep· April 2022

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Structural basis of adenylyl cyclase 9 activation.
Chao Qi, Pia Lavriha, Ved Mehta, Basavraj Khanppnavar, Inayathulla Mohammed, Birgit Dreier

Nat Commun· February 2022

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The RGD-binding integrins αvβ6 and αvβ8 are receptors for mouse adenovirus-1 and -3 infection.
Manuela Bieri, Rodinde Hendrickx, Michael Bauer, Bin Yu, Tania Jetzer, Birgit Dreier

PLoS Pathog· December 2021

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Designed Ankyrin Repeat Proteins as Novel Binders for Ultrasound Molecular Imaging.
Alexandra Kosareva, Mukesh Punjabi, Amanda Ochoa-Espinosa, Lifen Xu, Jonas V Schaefer, Birgit Dreier

Ultrasound Med Biol· September 2021

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Erratum: A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors.
Jessica Hartmann, Robert C Münch, Ruth-Therese Freiling, Irene C Schneider, Birgit Dreier

Mol Ther Methods Clin Dev· June 2021

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An Approach for the Real-Time Quantification of Cytosolic Protein-Protein Interactions in Living Cells.
Ilaria Incaviglia, Andreas Frutiger, Yves Blickenstorfer, Fridolin Treindl, Giulia Ammirati, Birgit Dreier

ACS Sens· April 2021

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Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins.
Kathrin Nowak, Florian Rosenthal, Tobias Karlberg, Mareike Bütepage, Ann-Gerd Thorsell, Birgit Dreier

Nat Commun· October 2020

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