Publications by authors named "Boris Ratnikov"

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Quantitative profiling of protease specificity.
Boris I Ratnikov, Piotr Cieplak, Albert G Remacle, Elise Nguyen, Jeffrey W Smith

PLoS Comput Biol· February 2021

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Predictive models of protease specificity based on quantitative protease-activity profiling data.
Gennady G Fedonin, Alexey Eroshkin, Piotr Cieplak, Evgenii V Matveev, Gennady V Ponomarev, Boris I Ratnikov

Biochim Biophys Acta Proteins Proteom· November 2019

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Correction: CleavPredict: A Platform for Reasoning about Matrix Metalloproteinases Proteolytic Events.
Sonu Kumar, Boris I Ratnikov, Marat D Kazanov, Jeffrey W Smith, Piotr Cieplak

PLoS One· May 2016

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CleavPredict: A Platform for Reasoning about Matrix Metalloproteinases Proteolytic Events.
Sonu Kumar, Boris I Ratnikov, Marat D Kazanov, Jeffrey W Smith, Piotr Cieplak

PLoS One· March 2016

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Right on TARGET: glutamine metabolism in cancer.
Boris Ratnikov, Young Joo Jeon, Jeffrey W Smith, Ze'ev A Ronai

Oncoscience· October 2015

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Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma.
Boris Ratnikov, Pedro Aza-Blanc, Ze'ev A Ronai, Jeffrey W Smith, Andrei L Osterman

Oncotarget· April 2015

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Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies.
Young Joo Jeon, Sihem Khelifa, Boris Ratnikov, David A Scott, Yongmei Feng

Cancer Cell· March 2015

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Basis for substrate recognition and distinction by matrix metalloproteinases.
Boris I Ratnikov, Piotr Cieplak, Kosi Gramatikoff, James Pierce, Alexey Eroshkin

Proc Natl Acad Sci U S A· October 2014

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Functional specialization in proline biosynthesis of melanoma.
Jessica De Ingeniis, Boris Ratnikov, Adam D Richardson, David A Scott, Pedro Aza-Blanc

PLoS One· February 2013

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Glutamine-fueled mitochondrial metabolism is decoupled from glycolysis in melanoma.
Fabian V Filipp, Boris Ratnikov, Jessica De Ingeniis, Jeffrey W Smith, Andrei L Osterman

Pigment Cell Melanoma Res· November 2012

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Discovery of amino acid motifs for thrombin cleavage and validation using a model substrate.
Natasha M Ng, James D Pierce, Geoffrey I Webb, Boris I Ratnikov, Lakshmi C Wijeyewickrema

Biochemistry· December 2011

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Structural determinants of limited proteolysis.
Marat D Kazanov, Yoshinobu Igarashi, Alexey M Eroshkin, Piotr Cieplak, Boris Ratnikov

J Proteome Res· August 2011

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Virtual ligand screening of the National Cancer Institute (NCI) compound library leads to the allosteric inhibitory scaffolds of the West Nile Virus NS3 proteinase.
Sergey A Shiryaev, Anton V Cheltsov, Katarzyna Gawlik, Boris I Ratnikov, Alex Y Strongin

Assay Drug Dev Technol· February 2011

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Internal cleavages of the autoinhibitory prodomain are required for membrane type 1 matrix metalloproteinase activation, although furin cleavage alone generates inactive proteinase.
Vladislav S Golubkov, Piotr Cieplak, Alexei V Chekanov, Boris I Ratnikov, Alexander E Aleshin

J Biol Chem· September 2010

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Isolation and characterization of selective and potent human Fab inhibitors directed to the active-site region of the two-component NS2B-NS3 proteinase of West Nile virus.
Sergey A Shiryaev, Ilian A Radichev, Boris I Ratnikov, Alexander E Aleshin, Katarzyna Gawlik

Biochem J· April 2010

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Recreation of the terminal events in physiological integrin activation.
Feng Ye, Guiqing Hu, Dianne Taylor, Boris Ratnikov, Andrey A Bobkov

J Cell Biol· January 2010

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Structure-activity relationship and improved hydrolytic stability of pyrazole derivatives that are allosteric inhibitors of West Nile Virus NS2B-NS3 proteinase.
Shyama Sidique, Sergey A Shiryaev, Boris I Ratnikov, Ananda Herath, Ying Su

Bioorg Med Chem Lett· October 2009

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Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis.
Sergey A Shiryaev, Albert G Remacle, Alexei Y Savinov, Andrei V Chernov, Piotr Cieplak, Boris I Ratnikov

J Biol Chem· October 2009

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High throughput substrate phage display for protease profiling.
Boris Ratnikov, Piotr Cieplak, Jeffrey W Smith

Methods Mol Biol· May 2009

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Matrix metalloproteinase proteolysis of the myelin basic protein isoforms is a source of immunogenic peptides in autoimmune multiple sclerosis.
Sergey A Shiryaev, Alexei Y Savinov, Piotr Cieplak, Boris I Ratnikov, Khatereh Motamedchaboki

PLoS One· April 2009

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PMAP: databases for analyzing proteolytic events and pathways.
Yoshinobu Igarashi, Emily Heureux, Kutbuddin S Doctor, Priti Talwar, Svetlana Gramatikova, Boris Ratnikov

Nucleic Acids Res· January 2009

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Substrate cleavage analysis of furin and related proprotein convertases. A comparative study.
Albert G Remacle, Sergey A Shiryaev, Eok-Soo Oh, Piotr Cieplak, Anupama Srinivasan, Boris I Ratnikov

J Biol Chem· July 2008

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The two-component NS2B-NS3 proteinase represses DNA unwinding activity of the West Nile virus NS3 helicase.
Andrei V Chernov, Sergey A Shiryaev, Alexander E Aleshin, Boris I Ratnikov, Jeffrey W Smith

J Biol Chem· June 2008

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Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B-NS3 proteinase.
Ilian Radichev, Sergey A Shiryaev, Alexander E Aleshin, Boris I Ratnikov, Jeffrey W Smith

J Gen Virol· March 2008

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HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus.
Paul A Johnston, Jennifer Phillips, Tong Ying Shun, Sunita Shinde, John S Lazo, Boris I Ratnikov

Assay Drug Dev Technol· December 2007

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