Publications by authors named "Brandon Hubbard"

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Cideb knockdown in mice increases mitochondrial fat oxidation and reverses hepatic steatosis and insulin resistance by the plasma membrane sn-1,2-DAGs-PKCε-insulin receptor kinase pathway.
Jie Zheng, Rafael C Gaspar, Ikki Sakuma, Brandon T Hubbard, Dongyan Zhang

Diabetologia· December 2025

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Hepatic ferredoxin reductase modulates mitochondrial function and iron homeostasis in metabolic dysfunction-associated steatotic liver disease.
Tomoaki Tanaka, Ikki Sakuma, Rafael Gaspar, Panu Luukkonen, Brandon Hubbard

Res Sq· August 2025

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SGLT2 inhibition alters substrate utilization and mitochondrial redox in healthy and failing rat hearts.
Leigh Goedeke, Yina Ma, Rafael C Gaspar, Ali Nasiri, Jieun Lee, Brandon T Hubbard

J Clin Invest· December 2024

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Cytosolic calcium regulates hepatic mitochondrial oxidation, intrahepatic lipolysis, and gluconeogenesis via CAMKII activation.
Traci E LaMoia, Brandon T Hubbard, Mateus T Guerra, Ali Nasiri, Ikki Sakuma

Cell Metab· October 2024

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Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease.
Rafael Calais Gaspar, Ikki Sakuma, Ali Nasiri, Brandon T Hubbard, Traci E LaMoia

Am J Physiol Endocrinol Metab· October 2024

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MAD2-Dependent Insulin Receptor Endocytosis Regulates Metabolic Homeostasis.
Junhee Park, Catherine Hall, Brandon Hubbard, Traci LaMoia, Rafael Gaspar

Diabetes· December 2023

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Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice.
Rafael C Gaspar, Kun Lyu, Brandon T Hubbard, Brooks P Leitner, Panu K Luukkonen

Diabetologia· March 2023

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Q-Flux: A method to assess hepatic mitochondrial succinate dehydrogenase, methylmalonyl-CoA mutase, and glutaminase fluxes in vivo.
Brandon T Hubbard, Traci E LaMoia, Leigh Goedeke, Rafael C Gaspar, Katrine D Galsgaard

Cell Metab· January 2023

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Systemic gene therapy for methylmalonic acidemia using the novel adeno-associated viral vector 44.9.
Randy J Chandler, Giovanni Di Pasquale, Jennifer L Sloan, Samantha McCoy, Brandon T Hubbard

Mol Ther Methods Clin Dev· December 2022

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Metformin, phenformin, and galegine inhibit complex IV activity and reduce glycerol-derived gluconeogenesis.
Traci E LaMoia, Gina M Butrico, Hasini A Kalpage, Leigh Goedeke, Brandon T Hubbard

Proc Natl Acad Sci U S A· March 2022

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Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia.
Randy J Chandler, Leah E Venturoni, Jing Liao, Brandon T Hubbard, Jessica L Schneller

Hepatology· June 2021

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Systemic AAV9 gene therapy improves the lifespan of mice with Niemann-Pick disease, type C1.
Randy J Chandler, Ian M Williams, Alana L Gibson, Cristin D Davidson, Arturo A Incao, Brandon T Hubbard

Hum Mol Genet· January 2017

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