Publications by authors named "Brandon Lowe"

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Recent progress in synthetic strategies to develop potent, HDAC8-selective, small-molecule inhibitors.
Brandon D Lowe, Steven Fletcher

Bioorg Med Chem Lett· December 2025

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The polypharmacy combination of the BCL-2 inhibitor venetoclax (VEN) and the FLT3 inhibitor gilteritinib (GIL) is more active in acute myeloid leukemia cells than novel polypharmacologic BCL-2/FLT3 VEN-GIL hybrid single-molecule inhibitors.
Christopher C Goodis, Christian Eberly, Alexandria M Chan, MinJung Kim, Brandon D Lowe

Eur J Med Chem· March 2025

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Genetic alteration of SJ293TS cells and modification of serum-free media enhances lentiviral vector production.
Matthew Bauler, Francesca Ferrara, Brandon Lowe, Jordan A Beard, Chris Wincek

Mol Ther Methods Clin Dev· June 2024

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Tetrazole and acylsulfonamide bioisosteric replacements of the carboxylic acid in a dual MCL-1/BCL-x inhibitor are tolerated.
Lijia Chen, Brandon Lowe, Steven Fletcher

RSC Adv· November 2023

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Expert Algorithm for Substance Identification Using Mass Spectrometry: Application to the Identification of Cocaine on Different Instruments Using Binary Classification Models.
Samantha A Mehnert, J Tyler Davidson, Alexandra Adeoye, Brandon D Lowe, Emily A Ruiz

J Am Soc Mass Spectrom· July 2023

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Expert Algorithm for Substance Identification Using Mass Spectrometry: Statistical Foundations in Unimolecular Reaction Rate Theory.
Glen P Jackson, Samantha A Mehnert, J Tyler Davidson, Brandon D Lowe, Emily A Ruiz

J Am Soc Mass Spectrom· July 2023

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Subtelomeric Chromatin in the Fission Yeast .
Rajesh K Yadav, Atsushi Matsuda, Brandon R Lowe, Yasushi Hiraoka, Janet F Partridge

Microorganisms· September 2021

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Submonomer synthesis of peptoids containing -inducing -imino- and -alkylamino-glycines.
Carolynn M Davern, Brandon D Lowe, Adam Rosfi, Elon A Ison, Caroline Proulx

Chem Sci· May 2021

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Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail.
Brandon R Lowe, Rajesh K Yadav, Ryan A Henry, Patrick Schreiner, Atsushi Matsuda

Elife· February 2021

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Histone H3 Mutations: An Updated View of Their Role in Chromatin Deregulation and Cancer.
Brandon R Lowe, Lily A Maxham, Joshua J Hamey, Marc R Wilkins, Janet F Partridge

Cancers (Basel)· May 2019

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Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in .
Rajesh K Yadav, Carolyn M Jablonowski, Alfonso G Fernandez, Brandon R Lowe, Ryan A Henry

Elife· July 2017

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SHREC Silences Heterochromatin via Distinct Remodeling and Deacetylation Modules.
Godwin Job, Christiane Brugger, Tao Xu, Brandon R Lowe, Yvan Pfister

Mol Cell· April 2016

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Histone H3 mutations--a special role for H3.3 in tumorigenesis?
Satish Kallappagoudar, Rajesh K Yadav, Brandon R Lowe, Janet F Partridge

Chromosoma· June 2015

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Cancer-associated mutants of RNA helicase DDX3X are defective in RNA-stimulated ATP hydrolysis.
Leslie B Epling, Christy R Grace, Brandon R Lowe, Janet F Partridge, Eric J Enemark

J Mol Biol· May 2015

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Sir2 is required for Clr4 to initiate centromeric heterochromatin assembly in fission yeast.
Benjamin J Alper, Godwin Job, Rajesh K Yadav, Sreenath Shanker, Brandon R Lowe

EMBO J· August 2013

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Centromeric heterochromatin assembly in fission yeast--balancing transcription, RNA interference and chromatin modification.
Benjamin J Alper, Brandon R Lowe, Janet F Partridge

Chromosome Res· July 2012

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