Publications by authors named "Bret Heale"

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Genetic data normalization for genomic medicine: a Fast Healthcare Interoperability Resources Genomics reference implementation.
Robert H Dolin, Nicolae-Mihai Todor, James Shalaby, Huda Arsalan, Eshani Shah, Bret S E Heale

J Am Med Inform Assoc· October 2025

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Molecularly-Guided Cancer Clinical Trial Matching using FHIR and HL7 Clinical Quality Language: A Proof of Concept.
Robert H Dolin, Waddah Arafat, Bret S E Heale, Edna Shenvi, Srikar Chamala

AMIA Annu Symp Proc· May 2025

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HerediGene Population Study IT infrastructure: A model to support genomic research recruitment and precision public health.
David P Taylor, Bret S E Heale, Benjamin Chisum, G Bryce Christensen, Darin F Wilcox

AMIA Annu Symp Proc· January 2024

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Sync for Genes Phase 5: Computable artifacts for sharing dynamically annotated FHIR-formatted genomic variants.
Robert Dolin, Bret S E Heale, Rohan Gupta, Carla Alvarez, Justin Aronson

Learn Health Syst· October 2023

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Automated HL7v2 LRI informatics framework for streamlining genomics-EHR data integration.
Robert H Dolin, Rohan Gupta, Kimberly Newsom, Bret S E Heale, Shailesh Gothi

J Pathol Inform· August 2023

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Introducing HL7 FHIR Genomics Operations: a developer-friendly approach to genomics-EHR integration.
Robert H Dolin, Bret S E Heale, Gil Alterovitz, Rohan Gupta, Justin Aronson

J Am Med Inform Assoc· February 2023

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The Development of an Infrastructure to Facilitate the Use of Whole Genome Sequencing for Population Health.
Nephi A Walton, Brent Hafen, Sara Graceffo, Nykole Sutherland, Melanie Emmerson, Bret Heale

J Pers Med· November 2022

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Creating a Home for Genomic Data in the Electronic Health Record.
Nephi Walton, Darren Johnson, Bret Heale, Thomas Person, Marc Williams

AMIA Annu Symp Proc· April 2022

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vcf2fhir: a utility to convert VCF files into HL7 FHIR format for genomics-EHR integration.
Robert H Dolin, Shaileshbhai R Gothi, Aziz Boxwala, Bret S E Heale, Ammar Husami

BMC Bioinformatics· March 2021

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Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling.
Ian M Overton, Andrew H Sims, Jeremy A Owen, Bret S E Heale, Matthew J Ford

Cancers (Basel)· September 2020

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FHIR Genomics: enabling standardization for precision medicine use cases.
Gil Alterovitz, Bret Heale, James Jones, David Kreda, Fan Lin

NPJ Genom Med· March 2020

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Lessons Learned in Creating Interoperable Fast Healthcare Interoperability Resources Profiles for Large-Scale Public Health Programs.
Susan A Matney, Bret Heale, Steve Hasley, Emily Decker, Brittni Frederiksen

Appl Clin Inform· January 2019

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Optimization of infobutton design and Implementation: A systematic review.
Miguel Teixeira, David A Cook, Bret S E Heale, Guilherme Del Fiol

J Biomed Inform· October 2017

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Physicians' pharmacogenomics information needs and seeking behavior: a study with case vignettes.
Bret S E Heale, Aly Khalifa, Bryan L Stone, Scott Nelson, Guilherme Del Fiol

BMC Med Inform Decis Mak· August 2017

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Context-sensitive decision support (infobuttons) in electronic health records: a systematic review.
David A Cook, Miguel T Teixeira, Bret Se Heale, James J Cimino, Guilherme Del Fiol

J Am Med Inform Assoc· March 2017

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Integrating Genomic Resources with Electronic Health Records using the HL7 Infobutton Standard.
Bret S E Heale, Casey Lynnette Overby, Guilherme Del Fiol, Wendy S Rubinstein, Donna R Maglott

Appl Clin Inform· August 2016

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The Effect of RNA Editing and ADARs on miRNA Biogenesis and Function.
Bret S E Heale, Liam P Keegan, Mary A O'Connell

Adv Exp Med Biol· April 2016

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Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNA.
Pierre Barraud, Bret S E Heale, Mary A O'Connell, Frédéric H-T Allain

Biochimie· July 2012

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RNA-sequencing analysis of 5' capped RNAs identifies many new differentially expressed genes in acute hepatitis C virus infection.
Neven Papic, Christopher I Maxwell, Don A Delker, Shuanghu Liu, Bret S E Heale

Viruses· April 2012

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The effect of RNA editing and ADARs on miRNA biogenesis and function.
Bret S E Heale, Liam P Keegan, Mary A O'Connell

Adv Exp Med Biol· June 2011

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Analysis of A to I editing of miRNA in macrophages exposed to Salmonella.
Bret S E Heale, Ana Eulalio, Leon Schulte, Jörg Vogel, Mary A O'Connell

RNA Biol· June 2011

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A role for human Dicer in pre-RISC loading of siRNAs.
Kumi Sakurai, Mohammed Amarzguioui, Dong-Ho Kim, Jessica Alluin, Bret Heale

Nucleic Acids Res· March 2011

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ADARs have effects beyond RNA editing.
Bret S E Heale, Liam P Keegan, Mary A O'Connell

Cell Cycle· December 2009

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Editing independent effects of ADARs on the miRNA/siRNA pathways.
Bret S E Heale, Liam P Keegan, Leeanne McGurk, Gracjan Michlewski, James Brindle

EMBO J· October 2009

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Potent siRNA inhibitors of ribonucleotide reductase subunit RRM2 reduce cell proliferation in vitro and in vivo.
Jeremy D Heidel, Joanna Yi-Ching Liu, Yun Yen, Bingsen Zhou, Bret S E Heale

Clin Cancer Res· April 2007

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