Publications by authors named "Brian Budzik"

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Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model.
Joseph E Pero, Jay M Matthews, David J Behm, Edward J Brnardic, Carl Brooks, Brian W Budzik

J Med Chem· December 2018

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The development of an in vitro assay to screen lipid based nanoparticles for siRNA delivery.
Ye Zhang, Leticia Arrington, David Boardman, Jared Davis, Yan Xu, Brian Budzik

J Control Release· January 2014

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Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists.
Jian Jin, Angel Morales-Ramos, Patrick Eidam, John Mecom, Yue Li, Brian Budzik

ACS Med Chem Lett· October 2010

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Novel N-Substituted Benzimidazolones as Potent, Selective, CNS-Penetrant, and Orally Active M1 mAChR Agonists.
Brian Budzik, Vincenzo Garzya, Dongchuan Shi, Graham Walker, Marie Woolley-Roberts

ACS Med Chem Lett· September 2010

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2' biaryl amides as novel and subtype selective M1 agonists. Part II: Further optimization and profiling.
Brian Budzik, Vincenzo Garzya, Dongchuan Shi, Graham Walker, Yann Lauchart

Bioorg Med Chem Lett· June 2010

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2' biaryl amides as novel and subtype selective M1 agonists. Part I: Identification, synthesis, and initial SAR.
Brian Budzik, Vincenzo Garzya, Dongchuan Shi, James J Foley, Ralph A Rivero

Bioorg Med Chem Lett· June 2010

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Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists.
Brian W Budzik, Karen A Evans, David D Wisnoski, Jian Jin, Ralph A Rivero

Bioorg Med Chem Lett· February 2010

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Discovery of 3-aryl-4-isoxazolecarboxamides as TGR5 receptor agonists.
Karen A Evans, Brian W Budzik, Sean A Ross, David D Wisnoski, Jian Jin

J Med Chem· December 2009

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M3 muscarinic acetylcholine receptor antagonists: SAR and optimization of bi-aryl amines.
Brian Budzik, Yonghui Wang, Dongchuan Shi, Feng Wang, Haibo Xie

Bioorg Med Chem Lett· March 2009

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Discovery of biphenyl piperazines as novel and long acting muscarinic acetylcholine receptor antagonists.
Jian Jin, Brian Budzik, Yonghui Wang, Dongchuan Shi, Feng Wang

J Med Chem· October 2008

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