Publications by authors named "Brian Burchell"

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A novel method for the immunoquantification of UDP-glucuronosyltransferases in human tissue.
Alison M Milne, Brian Burchell, Michael W H Coughtrie

Drug Metab Dispos· December 2011

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Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivation.
Benjamin C Lewis, Peter I Mackenzie, David J Elliot, Brian Burchell, C Ramana Bhasker

Biochem Pharmacol· May 2007

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Identification of the human liver UDP-glucuronosyltransferase involved in the metabolism of p-ethoxyphenylurea (dulcin).
Yoshihiro Uesawa, Adam G Staines, David Lockley, Kiminori Mohri, Brian Burchell

Arch Toxicol· March 2007

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Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family.
Tsutomu Kobayashi, Judith E Sleeman, Michael W H Coughtrie, Brian Burchell

Biochem J· December 2006

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Glucuronidation of SN-38 and NU/ICRF 505 in human colon cancer and adjacent normal colon.
Jeffrey Cummings, Brian T Ethell, Lesley Jardine, Brian Burchell

Anticancer Res· July 2006

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Substrate specificity of human hepatic udp-glucuronosyltransferases.
Brian Burchell, David J Lockley, Adam Staines, Yoshihiro Uesawa, Michael W H Coughtrie

Methods Enzymol· February 2006

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Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily.
Peter I Mackenzie, Karl Walter Bock, Brian Burchell, Chantal Guillemette, Shin-ichi Ikushiro

Pharmacogenet Genomics· October 2005

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Application of high-performance liquid chromatography-electrospray ionization-mass spectrometry to measure microsomal membrane transport of glucuronides.
Adam G Staines, Brian Burchell, Gábor Bánhegyi, József Mandl, Miklós Csala

Anal Biochem· July 2005

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N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7.
Adam G Staines, Michael W H Coughtrie, Brian Burchell

J Pharmacol Exp Ther· December 2004

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Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1.
Adam G Staines, Pavel Sindelar, Michael W H Coughtrie, Brian Burchell

Biochem J· December 2004

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Assessment of catechol induction and glucuronidation in rat liver microsomes.
Eivor Elovaara, Jouni Mikkola, Leena Luukkanen, Laurence Antonio, Sylvie Fournel-Gigleux, Brian Burchell

Drug Metab Dispos· December 2004

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Identification of the rabbit liver UDP-glucuronosyltransferase catalyzing the glucuronidation of 4-ethoxyphenylurea (dulcin).
Yoshihiro Uesawa, Adam G Staines, Audrey O'Sullivan, Kiminori Mohri, Brian Burchell

Drug Metab Dispos· December 2004

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Evidence for multiple glucuronide transporters in rat liver microsomes.
Miklós Csala, Adam G Staines, Gábor Bánhegyi, József Mandl, Michael W H Coughtrie, Brian Burchell

Biochem Pharmacol· October 2004

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Glucuronidation as a mechanism of intrinsic drug resistance in human colon cancer: reversal of resistance by food additives.
Jeffrey Cummings, Brian T Ethell, Lesley Jardine, Gary Boyd, Janet S Macpherson, Brian Burchell

Cancer Res· December 2003

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Genetic variation of human UDP-glucuronosyltransferase: implications in disease and drug glucuronidation.
Brian Burchell

Am J Pharmacogenomics· September 2003

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Conjugation of catechols by recombinant human sulfotransferases, UDP-glucuronosyltransferases, and soluble catechol O-methyltransferase: structure-conjugation relationships and predictive models.
Jyrki Taskinen, Brian T Ethell, Pia Pihlavisto, Alan M Hood, Brian Burchell

Drug Metab Dispos· September 2003

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Glucuronidation of HMR1098 in human microsomes: evidence for the involvement of UGT1A1 in the formation of S-glucuronides.
Brian T Ethell, Jens Riedel, Heinrich Englert, Herbert Jantz, Raymond Oekonomopulos, Brian Burchell

Drug Metab Dispos· August 2003

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The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases.
Brian T Ethell, Gail D Anderson, Brian Burchell

Biochem Pharmacol· May 2003

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Cloning and characterisation of the first drug-metabolising canine UDP-glucuronosyltransferase of the 2B subfamily.
Matthew G Soars, Michelle Fettes, Audrey C O'Sullivan, Robert J Riley, Brian T Ethell, Brian Burchell

Biochem Pharmacol· April 2003

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Glucuronidation of catechols by human hepatic, gastric, and intestinal microsomal UDP-glucuronosyltransferases (UGT) and recombinant UGT1A6, UGT1A9, and UGT2B7.
Laurence Antonio, Jing Xu, Joanna M Little, Brian Burchell, Jacques Magdalou

Arch Biochem Biophys· March 2003

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MRP1-transfected cells do not show increased resistance against oxidative stress.
Aneta Balcerczyk, Błazej Rychlik, Marcin Kruszewski, Brian Burchell, Grzegorz Bartosz

Free Radic Res· February 2003

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Histone 2A stimulates glucose-6-phosphatase activity by permeabilization of liver microsomes.
Angelo Benedetti, Rosella Fulceri, Bernard B Allan, Pamela Houston, Andrey L Sukhodub, Brian Burchell, Ann Burchell

Biochem J· October 2002

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Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases.
Kenneth F Ilett, Brian T Ethell, James L Maggs, Timothy M E Davis, Kevin T Batty, Brian Burchell

Drug Metab Dispos· September 2002

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Quantitative structure activity relationships for the glucuronidation of simple phenols by expressed human UGT1A6 and UGT1A9.
Brian T Ethell, Sean Ekins, Jibo Wang, Brian Burchell

Drug Metab Dispos· June 2002

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The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.
Claire Senay, Gabriele Jedlitschky, Nadège Terrier, Brian Burchell, Jacques Magdalou

Biochim Biophys Acta· May 2002

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