Publications by authors named "David J Elliot"

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The Combination of Metformin and Valproic Acid Has a Greater Anti-tumoral Effect on Prostate Cancer Growth than Either Drug Alone.
Linh N K Tran, Ganessan Kichenadasse, Katherine L Morel, Tina C Lavranos, Sonja Klebe, David J Elliot

In Vivo· April 2019

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Quantitative mass spectrometry to identify protein markers for diagnosis of malignant pleural mesothelioma.
Reuben White, Emily Pulford, David J Elliot, Lauren A Thurgood, Sonja Klebe

J Proteomics· February 2019

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In vitro metabolism of the anti-inflammatory clerodane diterpenoid polyandric acid A and its hydrolysis product by human liver microsomes and recombinant cytochrome P450 and UDP-glucuronosyltransferase enzymes.
Matthew Y Bendikov, John O Miners, Bradley S Simpson, David J Elliot, Susan J Semple

Xenobiotica· June 2017

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Morphine glucuronidation and glucosidation represent complementary metabolic pathways that are both catalyzed by UDP-glucuronosyltransferase 2B7: kinetic, inhibition, and molecular modeling studies.
Nuy Chau, David J Elliot, Benjamin C Lewis, Kushari Burns, Martin R Johnston

J Pharmacol Exp Ther· April 2014

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Measurement of human cytochrome P4501A2 (CYP1A2) activity in vitro.
Thomas M Polasek, David J Elliot, John O Miners

Curr Protoc Toxicol· February 2013

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Effect of albumin on human liver microsomal and recombinant CYP1A2 activities: impact on in vitro-in vivo extrapolation of drug clearance.
Nitsupa Wattanachai, Wichittra Tassaneeyakul, Andrew Rowland, David J Elliot, Kushari Bowalgaha

Drug Metab Dispos· May 2012

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Application of the fluorescent probe 1-anilinonaphthalene-8-sulfonate to the measurement of the nonspecific binding of drugs to human liver microsomes.
James A McLure, Donald J Birkett, David J Elliot, J Andrew Williams, Andrew Rowland

Drug Metab Dispos· September 2011

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Characterization of niflumic acid as a selective inhibitor of human liver microsomal UDP-glucuronosyltransferase 1A9: application to the reaction phenotyping of acetaminophen glucuronidation.
John O Miners, Kushari Bowalgaha, David J Elliot, Pawel Baranczewski, Kathleen M Knights

Drug Metab Dispos· April 2011

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The novel UDP glycosyltransferase 3A2: cloning, catalytic properties, and tissue distribution.
Peter I MacKenzie, Anne Rogers, David J Elliot, Nuy Chau, Julie-Ann Hulin

Mol Pharmacol· March 2011

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In vitro-in vivo extrapolation predicts drug-drug interactions arising from inhibition of codeine glucuronidation by dextropropoxyphene, fluconazole, ketoconazole, and methadone in humans.
Pritsana Raungrut, Verawan Uchaipichat, David J Elliot, Benjamas Janchawee, Andrew A Somogyi

J Pharmacol Exp Ther· August 2010

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In vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A.
Thomas M Polasek, Janani S Sadagopal, David J Elliot, John O Miners

Eur J Clin Pharmacol· March 2010

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Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.
Kathleen M Knights, Leanne K Winner, David J Elliot, Kushari Bowalgaha, John O Miners

Br J Clin Pharmacol· September 2009

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In vitro characterisation of human renal and hepatic frusemide glucuronidation and identification of the UDP-glucuronosyltransferase enzymes involved in this pathway.
Oranun Kerdpin, Kathleen M Knights, David J Elliot, John O Miners

Biochem Pharmacol· July 2008

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The "albumin effect" and in vitro-in vivo extrapolation: sequestration of long-chain unsaturated fatty acids enhances phenytoin hydroxylation by human liver microsomal and recombinant cytochrome P450 2C9.
Andrew Rowland, David J Elliot, Kathleen M Knights, Peter I Mackenzie, John O Miners

Drug Metab Dispos· May 2008

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Influence of mutations associated with Gilbert and Crigler-Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates.
Wandee Udomuksorn, David J Elliot, Benjamin C Lewis, Peter I Mackenzie, Krongtong Yoovathaworn

Pharmacogenet Genomics· December 2007

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Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination.
David J Elliot, Suharjono, Benjamin C Lewis, Elizabeth M J Gillam, Donald J Birkett

Br J Clin Pharmacol· October 2007

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Critical roles of residues 36 and 40 in the phenol and tertiary amine aglycone substrate selectivities of UDP-glucuronosyltransferases 1A3 and 1A4.
Takahiro Kubota, Benjamin C Lewis, David J Elliot, Peter I Mackenzie, John O Miners

Mol Pharmacol· October 2007

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Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivation.
Benjamin C Lewis, Peter I Mackenzie, David J Elliot, Brian Burchell, C Ramana Bhasker

Biochem Pharmacol· May 2007

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Binding of inhibitory fatty acids is responsible for the enhancement of UDP-glucuronosyltransferase 2B7 activity by albumin: implications for in vitro-in vivo extrapolation.
Andrew Rowland, Paraskevi Gaganis, David J Elliot, Peter I Mackenzie, Kathleen M Knights

J Pharmacol Exp Ther· April 2007

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Sulfinpyrazone C-glucuronidation is catalyzed selectively by human UDP-glucuronosyltransferase 1A9.
Oranun Kerdpin, David J Elliot, Peter I Mackenzie, John O Miners

Drug Metab Dispos· December 2006

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In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction.
Andrew Rowland, David J Elliot, J Andrew Williams, Peter I Mackenzie, Ronald G Dickinson

Drug Metab Dispos· June 2006

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An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid.
Thomas M Polasek, David J Elliot, Andrew A Somogyi, Elizabeth M J Gillam, Benjamin C Lewis

Br J Clin Pharmacol· May 2006

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Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation.
Verawan Uchaipichat, Leanne K Winner, Peter I Mackenzie, David J Elliot, J Andrew Williams

Br J Clin Pharmacol· April 2006

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Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) "probes" for human udp-glucuronosyltransferases.
Verawan Uchaipichat, Peter I Mackenzie, David J Elliot, John O Miners

Drug Metab Dispos· March 2006

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S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.
Kushari Bowalgaha, David J Elliot, Peter I Mackenzie, Kathleen M Knights, Stellan Swedmark

Br J Clin Pharmacol· October 2005

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