Publications by authors named "Brian Hubbard"

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The private well water climate impact index: Characterization of community-level climate-related hazards and vulnerability in the continental United States.
Komal Peer, Brian Hubbard, Michele Monti, Patrick Vander Kelen, Angela K Werner

Sci Total Environ· December 2024

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BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models.
Ulrike Rauh, Guo Wei, Michael Serrano-Wu, Georgios Kosmidis, Stefan Kaulfuss, Brian Hubbard

Nat Cancer· October 2024

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Assessing state partner use of the Model Aquatic Health Code (MAHC): A cross comparison of five states with varying degrees of self-reported adoption status.
Patrick Vander Kelen, Joseph P Laco, Shannon McClenahan, Christopher Fletcher, Brian Hubbard

PLOS Water· August 2024

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Racial Disparities in Incidence of Legionnaires' Disease and Social Determinants of Health: A Narrative Review.
Candis M Hunter, Simone W Salandy, Jessica C Smith, Chris Edens, Brian Hubbard

Public Health Rep· July 2022

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Preclinical Development of Pentamidine Analogs Identifies a Potent and Nontoxic Antibiotic Adjuvant.
Craig R MacNair, Maya A Farha, Michael H Serrano-Wu, Katie K Lee, Brian Hubbard

ACS Infect Dis· April 2022

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Allosteric MAPKAPK2 inhibitors improve plaque stability in advanced atherosclerosis.
Lale Ozcan, Canan Kasikara, Arif Yurdagul, George Kuriakose, Brian Hubbard

PLoS One· October 2021

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Chemical Screen for Vancomycin Antagonism Uncovers Probes of the Gram-Negative Outer Membrane.
Kristina Klobucar, Jean-Philippe Côté, Shawn French, Louis Borrillo, Amelia Bing Ya Guo, Brian Hubbard

ACS Chem Biol· May 2021

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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Whitney L Petrilli, Gregory C Adam, Roman S Erdmann, Pravien Abeywickrema, Vijayalakshmi Agnani, Brian Hubbard

Cell Chem Biol· February 2021

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A Methodology for Classifying Root Causes of Outbreaks of Legionnaires' Disease: Deficiencies in Environmental Control and Water Management.
Benjamin R Clopper, Jasen M Kunz, Simone W Salandy, Jessica C Smith, Brian C Hubbard

Microorganisms· January 2021

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Tools To Help Conquer The Model Aquatic Health Code.
Joe Laco, Brian Hubbard, Shannon McClenahan

J Environ Health· May 2020

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From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.
Whitney L Petrilli, Gregory C Adam, Roman S Erdmann, Pravien Abeywickrema, Vijayalakshmi Agnani, Brian Hubbard

Cell Chem Biol· January 2020

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Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.
Eachan O Johnson, Emily LaVerriere, Emma Office, Mary Stanley, Elisabeth Meyer, Brian K Hubbard

Nature· July 2019

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Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors.
Chao Fang, Katie K Lee, Raymond Nietupski, Robert H Bates, Raquel Fernandez-Menendez, Brian K Hubbard

Bioorg Med Chem Lett· December 2018

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Session 1.5: other viral clearance and inactivation approaches (multimodal chromatography, membrane chromatography, chemical precipitation).
Brian Hubbard

PDA J Pharm Sci Technol· October 2018

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Innovative Safe Water Program Improvement E-Learning for Environmental Health Professionals.
Raquel Sabogal, Martin Kalis, Brian Hubbard, John Oeffinger, Liljana Johnson Baddour

J Environ Health· June 2018

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CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects.
Tiffany Thomas, Haihong Zhou, Wahida Karmally, Rajasekhar Ramakrishnan, Stephen Holleran, Brian Hubbard

Arterioscler Thromb Vasc Biol· September 2017

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Discovery of an Orally Bioavailable Benzimidazole Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor That Suppresses Body Weight Gain in Diet-Induced Obese Dogs and Postprandial Triglycerides in Humans.
Katsumasa Nakajima, Ricardo Chatelain, Kevin B Clairmont, Renee Commerford, Gary M Coppola, Brian K Hubbard

J Med Chem· June 2017

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Lessons From an Outbreak of Legionnaires' Disease on a Hematology-Oncology Unit.
Louise K Francois Watkins, Karrie-Ann E Toews, Aaron M Harris, Sherri Davidson, Stephanie Ayers-Millsap, Brian C Hubbard

Infect Control Hosp Epidemiol· March 2017

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What Actions Are Health Departments Taking to Improve Safe Drinking Water Programs?
Vanessa Lamers, Brian C Hubbard

J Environ Health· March 2017

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Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor.
Colin W Garvie, Cara V Fraley, Nadine H Elowe, Elizabeth K Culyba, Christopher T Lemke, Brian K Hubbard

Protein Sci· November 2016

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Effect of Error Propagation in Stable Isotope Tracer Studies: An Approach for Estimating Impact on Apparent Biochemical Flux.
Stephen F Previs, Kithsiri Herath, Jose Castro-Perez, Ablatt Mahsut, Haihong Zhou, Brian K Hubbard

Methods Enzymol· June 2016

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A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.
Matthew C Clifton, David M Dranow, Alison Leed, Ben Fulroth, James W Fairman, Brian K Hubbard

PLoS One· April 2016

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Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors.
Jason E Imbriglio, Dong-Ming Shen, Rui Liang, Ken Marby, Ming You, Brian K Hubbard

J Med Chem· December 2015

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Improving State and Local Capacity to Assess and Manage Risks Associated With Private Wells and Other Drinking Water Systems Not Covered by the Safe Drinking Water Act.
Raquel I Sabogal, Brian Hubbard

J Environ Health· December 2015

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Treatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin Sensitivity.
Lale Ozcan, Xiaoming Xu, Shi-Xian Deng, Devram S Ghorpade, Tiffany Thomas, Brian Hubbard

Diabetes· October 2015

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