Publications by authors named "Brian Lockhart"

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Genetically Distinct Acute Megakaryoblastic Leukemia following Low Hypodiploid B-Lymphoblastic Leukemia linked by Mutation.
Jaryse C Harris, Jeffrey Schubert, Brian Lockhart, Rachel Olson, Michele E Paessler

Pediatr Dev Pathol· May 2025

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A perspective review on the systematic implementation of ctDNA in phase I clinical trial drug development.
Nolwen Guigal-Stephan, Brian Lockhart, Tina Moser, Ellen Heitzer

J Exp Clin Cancer Res· March 2025

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Maturational dyssynchrony in benign B-cell precursors following lymphocyte depleting chemotherapy: A potential pitfall for B-lymphoblastic leukemia minimal/measurable residual disease (MRD) flow cytometry analysis.
Alexander Placek, Brian Lockhart, Karin P Miller, Gerald B Wertheim, Shannon L Maude

Cytometry B Clin Cytom· March 2024

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Bone marrow fibrosis is associated with non-response to CD19 CAR T-cell therapy in B-acute lymphoblastic leukemia.
Joshua Anil, Ahab Alnemri, Andrew Lytle, Brian Lockhart, Ashley E Anil

Am J Hematol· December 2023

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Proteogenomic Profiling of High-Grade B-Cell Lymphoma With 11q Aberrations and Burkitt Lymphoma Reveals Lymphoid Enhancer Binding Factor 1 as a Novel Biomarker.
Stephanie N Hurwitz, Brian Lockhart, Özlem Önder, Rui Wu, Shenon Sethi

Mod Pathol· July 2023

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Haematology laboratory parameters to assess efficacy of CD19-, CD22-, CD33-, and CD123-directed chimeric antigen receptor T-cell therapy in haematological malignancies.
Bradley Drumheller, Kirubel Gebre, Brian Lockhart, Elizabeth Margolskee, Amrom Obstfeld

Int J Lab Hematol· August 2022

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Intensity and mode of reproduction are affected by flooding and light availability.
Theodor D Leininger, Emile S Gardiner, Brian Roy Lockhart, Nathan M Schiff, Alphus Dan Wilson

Ecol Evol· October 2021

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Shallow Whole-Genome Sequencing from Plasma Identifies FGFR1 Amplified Breast Cancers and Predicts Overall Survival.
Chantal Bourrier, Jean-Yves Pierga, Laura Xuereb, Hélène Salaun, Charlotte Proudhon, Brian Paul Lockhart

Cancers (Basel)· June 2020

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Implications of Mitochondrial Dysfunction for the Anesthetic and Perioperative Management: A Case Report of Spinal Fusion, Genetic Confusion, and a Patient's Perspective.
Linda S Aglio, Brian T Lockhart, Jeantine E Lunshof, Christoph S Nabzdyk

A A Pract· March 2018

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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models.
András Kotschy, Zoltán Szlavik, James Murray, James Davidson, Ana Leticia Maragno, Brian Lockhart

Nature· October 2016

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HDAC inhibition does not induce estrogen receptor in human triple-negative breast cancer cell lines and patient-derived xenografts.
Patricia de Cremoux, Mathieu Dalvai, Olivia N'Doye, Fatima Moutahir, Gaëlle Rolland, Brian Paul Lockhart

Breast Cancer Res Treat· January 2015

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Targeting Bcl-2/Bcl-XL induces antitumor activity in uveal melanoma patient-derived xenografts.
Fariba Némati, Catherine de Montrion, Guillaume Lang, Laurence Kraus-Berthier, Guillaume Carita, Brian Lockhart

PLoS One· September 2014

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Analysis of sterol-regulatory element-binding protein 1c target genes in mouse liver during aging and high-fat diet.
Frédéric Capel, Gaëlle Rolland-Valognes, Catherine Dacquet, Manuel Brun, Michel Lonchampt, Brian Lockhart

J Nutrigenet Nutrigenomics· January 2014

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Applying systems biology in drug discovery and development.
Jean-Pierre Galizzi, Brian Paul Lockhart, Antoine Bril

Drug Metabol Drug Interact· September 2013

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S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab.
Mike F Burbridge, Céline J Bossard, Carine Saunier, Imre Fejes, Alain Bruno, Brian P Lockhart

Mol Cancer Ther· September 2013

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Blockade of α2-adrenoceptors induces Arc gene expression in rat brain in a glutamate receptor-dependent manner: a combined qPCR, in situ hybridisation and immunocytochemistry study.
Florence Serres, Marianne Rodriguez, Jean-Michel Rivet, Jean-Pierre Galizzi, Brian Lockhart

Neuropharmacology· November 2012

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RhoA guanine exchange factor expression profile in arteries: evidence for a Rho kinase-dependent negative feedback in angiotensin II-dependent hypertension.
Chrystelle Cario-Toumaniantz, David Ferland-McCollough, Gilliane Chadeuf, Gilles Toumaniantz, Marianne Rodriguez, Brian Lockhart

Am J Physiol Cell Physiol· May 2012

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Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA).
Benjamin Di Cara, Roberto Maggio, Gabriella Aloisi, Jean-Michel Rivet, Ebba Gregorsson Lundius, Brian P Lockhart

J Neurosci· November 2011

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Neuropilin-1 is upregulated in hepatocellular carcinoma and contributes to tumour growth and vascular remodelling.
Mathieu Bergé, David Allanic, Philippe Bonnin, Catherine de Montrion, Johann Richard, Brian P Lockhart

J Hepatol· October 2011

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Molecular characterization of the AMPA-receptor potentiator S70340 in rat primary cortical culture: whole-genome expression profiling.
Sophie Mourlevat, Jean-Pierre Galizzi, Nolwen Guigal-Stéphan, Sophie Courtade-Gaïani, Gaëlle Rolland-Valognes, Brian Paul Lockhart

Neurosci Res· August 2011

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Only a subset of Met-activated pathways are required to sustain oncogene addiction.
Andrea Bertotti, Mike F Burbridge, Stefania Gastaldi, Francesco Galimi, Davide Torti, Brian P Lockhart

Sci Signal· March 2011

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Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells.
Florence Sancier, Aurélie Dumont, Audrey Sirvent, Ludmilla Paquay de Plater, Thomas Edmonds, Brian Lockhart

PLoS One· February 2011

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Only a subset of Met-activated pathways are required to sustain oncogene addiction.
Andrea Bertotti, Mike F Burbridge, Stefania Gastaldi, Francesco Galimi, Davide Torti, Brian P Lockhart

Sci Signal· December 2009

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Nox4 mediates the expression of plasminogen activator inhibitor-1 via p38 MAPK pathway in cultured human endothelial cells.
Amandine Jaulmes, Patricia Sansilvestri-Morel, Gaëlle Rolland-Valognes, Fabienne Bernhardt, Roger Gaertner, Brian P Lockhart

Thromb Res· September 2009

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Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker.
Melis Karaca, Julien Castel, Cécile Tourrel-Cuzin, Manuel Brun, Anne Géant, Brian Lockhart

PLoS One· August 2009

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