Publications by authors named "Brian Ruis"

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TET1 functions as a tumor suppressor in lung adenocarcinoma through epigenetic remodeling and immune modulation.
Abdur Rahim, Brian L Ruis, Andrew T Rajczewski, Monica E Kruk, Natalia Y Tretyakova

Epigenetics Chromatin· August 2025

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Gene editing and CRISPR-dependent homology-mediated end joining.
Brian L Ruis, Anja K Bielinsky, Eric A Hendrickson

Exp Mol Med· July 2025

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An antioxidant response element regulates the HIF1α axis in breast cancer cells.
Sarah E Lacher, Cara Skon-Hegg, Brian L Ruis, Jennifer Krznarich, Matthew Slattery

Free Radic Biol Med· August 2023

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Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles.
Hillary P Handler, Lisa Duvick, Jason S Mitchell, Marija Cvetanovic, Molly Reighard, Brian L Ruis

Neuron· February 2023

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A dominant function of LynB kinase in preventing autoimmunity.
Ben F Brian, Monica L Sauer, Joseph T Greene, S Erandika Senevirathne, Anders J Lindstedt, Brian L Ruis

Sci Adv· April 2022

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Absence of XRCC4 and its paralogs in human cells reveal differences in outcomes for DNA repair and V(D)J recombination.
Brian Ruis, Amy Molan, Taylor Takasugi, Eric A Hendrickson

DNA Repair (Amst)· January 2020

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DNA Ligase 1 is an essential mediator of sister chromatid telomere fusions in G2 cell cycle phase.
Kate Liddiard, Brian Ruis, Yinan Kan, Kez Cleal, Kevin E Ashelford

Nucleic Acids Res· March 2019

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TDP1 suppresses mis-joining of radiomimetic DNA double-strand breaks and cooperates with Artemis to promote optimal nonhomologous end joining.
Ajinkya S Kawale, Konstantin Akopiants, Kristoffer Valerie, Brian Ruis, Eric A Hendrickson

Nucleic Acids Res· September 2018

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Mechanisms of precise genome editing using oligonucleotide donors.
Yinan Kan, Brian Ruis, Taylor Takasugi, Eric A Hendrickson

Genome Res· July 2017

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Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4.
Kate Liddiard, Brian Ruis, Taylor Takasugi, Adam Harvey, Kevin E Ashelford

Genome Res· May 2016

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Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.
Hind Ghezraoui, Marion Piganeau, Benjamin Renouf, Jean-Baptiste Renaud, Annahita Sallmyr, Brian Ruis

Mol Cell· September 2014

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The mechanism of gene targeting in human somatic cells.
Yinan Kan, Brian Ruis, Sherry Lin, Eric A Hendrickson

PLoS Genet· April 2014

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The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells.
Brian L Ruis, Kazi R Fattah, Eric A Hendrickson

Mol Cell Biol· October 2008

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Mutations to Ku reveal differences in human somatic cell lines.
Kazi R Fattah, Brian L Ruis, Eric A Hendrickson

DNA Repair (Amst)· May 2008

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NOM1 targets protein phosphatase I to the nucleolus.
Shanaka R Gunawardena, Brian L Ruis, Julia A Meyer, Meenal Kapoor, Kathleen F Conklin

J Biol Chem· January 2008

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Identification of NOM1, a nucleolar, eIF4A binding protein encoded within the chromosome 7q36 breakpoint region targeted in cases of pediatric acute myeloid leukemia.
Heidi M Simmons, Brian L Ruis, Meenal Kapoor, Andrew W Hudacek, Kathleen F Conklin

Gene· February 2005

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