Publications by authors named "Brian Untch"

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Multifocality in sporadic medullary thyroid carcinoma is associated with low tumor grade and no difference in somatic driver mutations or overall survival when compared with unifocal tumors.
Aradhya Nigam, Michael A Mederos, Yagiz A Aksoy, Bayan Alzumaili, Mohamed-Amine Bani, Brian R Untch

Surgery· January 2026

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ctDNA as a Molecular Biomarker in the Phase II Trial of Imatinib plus Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumor.
Ciara M Kelly, Martina Bradic, Sara Saunds, Viswatej Avutu, Lauren Banks, Brian R Untch

Clin Cancer Res· October 2025

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RBM10 loss promotes metastases by aberrant splicing of cytoskeletal and extracellular matrix mRNAs.
Gnana P Krishnamoorthy, Anthony R Glover, Brian R Untch, Nickole Sigcha-Coello, Bin Xu

J Exp Med· May 2025

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Clinical and Pathologic Characteristics of Cytologically Indeterminate Thyroid Nodules with Non-V600E Alterations.
Ryan Instrum, Christina E Swartzwelder, Ronald A Ghossein, Bin Xu, Babak Givi, Brian R Untch

Cancers (Basel)· February 2025

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Targetable treatment resistance in thyroid cancer with clonal hematopoiesis.
Vera Tiedje, Pablo Sánchez Vela, Julie L Yang, Brian R Untch, Laura Boucai

bioRxiv· October 2024

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Cooperative genomic lesions in HRAS-mutant cancers predict resistance to farnesyltransferase inhibitors.
Aradhya Nigam, Gnana P Krishnamoorthy, Walid K Chatila, Katherine Berman, Mahesh Saqcena, Brian R Untch

Oncogene· September 2024

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RBM10 loss induces aberrant splicing of cytoskeletal and extracellular matrix mRNAs and promotes metastatic fitness.
Gnana P Krishnamoorthy, Anthony R Glover, Brian R Untch, Nickole Sigcha-Coello, Bin Xu

bioRxiv· July 2024

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Novel prognostic nomogram for predicting recurrence-free survival in medullary thyroid carcinoma.
Yagiz A Aksoy, Bin Xu, Kartik Viswanathan, Mahsa S Ahadi, Abir Al Ghuzlan, Brian R Untch

Histopathology· May 2024

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Morbidity and Outcomes of Primary Tumor Management in Patients with Widely Metastatic Well-Differentiated Small Bowel Neuroendocrine Tumors.
Aradhya Nigam, Janet W Y Li, Megan Fiasconaro, Sabrina Lin, Marinela Capanu, Brian R Untch

Ann Surg Oncol· April 2024

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ASO Author Reflections: Morbidity and Outcomes of Primary Tumor Management in Patients with Widely Metastatic Well-Differentiated Small Bowel Neuroendocrine Tumors.
Aradhya Nigam, Brian R Untch

Ann Surg Oncol· April 2024

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-Mutated Cytologically Indeterminate Thyroid Nodules: Prevalence of Malignancy and Behavior Under Active Surveillance.
Hannah J Sfreddo, Elizabeth S Koh, Karena Zhao, Christina E Swartzwelder, Brian R Untch

Thyroid· April 2024

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Association of the Genomic Profile of Medullary Thyroid Carcinoma with Tumor Characteristics and Clinical Outcomes in an International Multicenter Study.
Bin Xu, Kartik Viswanathan, Mahsa S Ahadi, Sara Ahmadi, Bayan Alzumaili, Brian Untch

Thyroid· February 2024

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Expert Consensus Practice Recommendations of the North American Neuroendocrine Tumor Society for the management of high grade gastroenteropancreatic and gynecologic neuroendocrine neoplasms.
Jennifer R Eads, Thorvardur R Halfdanarson, Tim Asmis, Andrew M Bellizzi, Emily K Bergsland, Brian Untch

Endocr Relat Cancer· August 2023

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Cooperative Genomic Lesions in HRAS-Mutant Cancers Predict Resistance to Farnesyltransferase Inhibitors.
Aradhya Nigam, Gnana Krishnamoorthy, Walid Chatila, Katherine Berman, Mahesh Saqcena, Brian Untch

Res Sq· July 2023

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Active Surveillance of Papillary Thyroid Cancer: Frequency and Time Course of the Six Most Common Tumor Volume Kinetic Patterns.
Robert Michael Tuttle, James Fagin, Gerald Minkowitz, Richard Wong, Benjamin Roman, Brian Untch

Thyroid· November 2022

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Tumor Grade Predicts for Calcitonin Doubling Times and Disease-Specific Outcomes After Resection of Medullary Thyroid Carcinoma.
Aradhya Nigam, Bin Xu, Philip M Spanheimer, Ian Ganly, R Michael Tuttle, Brian R Untch

Thyroid· October 2022

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Primary Mesenchymal Tumors of the Thyroid Gland: A Modern Retrospective Cohort Including the First Case of TFE3-Translocated Malignant Perivascular Epithelioid Cell Tumor (PEComa).
Lingxin Zhang, Daniel Lubin, John H Sinard, Brendan C Dickson, Cristina R Antonescu, Brian R Untch

Head Neck Pathol· September 2022

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FGFR2::TACC2 fusion as a novel KIT-independent mechanism of targeted therapy failure in a multidrug-resistant gastrointestinal stromal tumor.
Josephine K Dermawan, Chad M Vanderbilt, Jason C Chang, Brian R Untch, Samuel Singer

Genes Chromosomes Cancer· July 2022

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Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets.
Benjamin A Nacev, Francisco Sanchez-Vega, Shaleigh A Smith, Cristina R Antonescu, Evan Rosenbaum, Brian R Untch

Nat Commun· June 2022

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Genomic and Transcriptomic Correlates of Thyroid Carcinoma Evolution after BRAF Inhibitor Therapy.
Mark Lee, Brian R Untch, Bin Xu, Ronald Ghossein, Catherine Han

Mol Cancer Res· January 2022

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International Medullary Thyroid Carcinoma Grading System: A Validated Grading System for Medullary Thyroid Carcinoma.
Bin Xu, Talia L Fuchs, Sara Ahmadi, Mohammed Alghamdi, Bayan Alzumaili, Brian R Untch

J Clin Oncol· January 2022

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Prophylactic Lateral Neck Dissection for Medullary Thyroid Carcinoma is not Associated with Improved Survival.
Philip M Spanheimer, Ian Ganly, Joanne F Chou, Marinela Capanu, Aradhya Nigam, Brian R Untch

Ann Surg Oncol· October 2021

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Predicting malignancy in patients with adrenal tumors using F-FDG-PET/CT SUVmax.
Elvira L Vos, Ravinder K Grewal, Ashley E Russo, Diane Reidy-Lagunes, Brian R Untch

J Surg Oncol· December 2020

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Grading of medullary thyroid carcinoma on the basis of tumor necrosis and high mitotic rate is an independent predictor of poor outcome.
Bayan Alzumaili, Bin Xu, Philip M Spanheimer, R Michael Tuttle, Eric Sherman, Brian R Untch

Mod Pathol· September 2020

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PD-1 Blockade in Advanced Adrenocortical Carcinoma.
Nitya Raj, Youyun Zheng, Virginia Kelly, Seth S Katz, Joanne Chou, Brian R Untch

J Clin Oncol· January 2020

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