Publications by authors named "Brigham Hartley"

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A repository of Ogden syndrome patient derived iPSC lines and isogenic pairs by X-chromosome screening and genome-editing.
Josephine Wesely, Tom Rusielewicz, Yu-Ren Chen, Brigham Hartley, Dayna McKenzie

bioRxiv· September 2024

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Activity-Dependent Transcriptional Program in NGN2+ Neurons Enriched for Genetic Risk for Brain-Related Disorders.
Yixuan Ma, Jaroslav Bendl, Brigham J Hartley, John F Fullard, Rawan Abdelaal

Biol Psychiatry· January 2024

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Beta-blockade enhances anthracycline control of metastasis in triple-negative breast cancer.
Aeson Chang, Edoardo Botteri, Ryan D Gillis, Lukas Löfling, Caroline P Le, Brigham J Hartley

Sci Transl Med· April 2023

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A bidirectional competitive interaction between circHomer1 and Homer1b within the orbitofrontal cortex regulates reversal learning.
Alexander K Hafez, Amber J Zimmerman, Grigorios Papageorgiou, Jayapriya Chandrasekaran, Stephen K Amoah, Brigham J Hartley

Cell Rep· January 2022

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A psychiatric disease-related circular RNA controls synaptic gene expression and cognition.
Amber J Zimmerman, Alexander K Hafez, Stephen K Amoah, Brian A Rodriguez, Michela Dell'Orco, Brigham J Hartley

Mol Psychiatry· November 2020

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Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression.
Orna Issler, Yentl Y van der Zee, Aarthi Ramakrishnan, Junshi Wang, Chunfeng Tan, Brigham J Hartley

Neuron· June 2020

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Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia.
Benjamin Readhead, Brigham J Hartley, Brian J Eastwood, David A Collier, David Evans

Nat Commun· November 2018

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Expression-based drug screening of neural progenitor cells from individuals with schizophrenia.
Benjamin Readhead, Brigham J Hartley, Brian J Eastwood, David A Collier, David Evans

Nat Commun· October 2018

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In utero exposure to maternal smoking is associated with DNA methylation alterations and reduced neuronal content in the developing fetal brain.
Zac Chatterton, Brigham J Hartley, Man-Ho Seok, Natalia Mendelev, Sean Chen

Epigenetics Chromatin· January 2018

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Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.
Gabriel E Hoffman, Brigham J Hartley, Erin Flaherty, Ian Ladran, Peter Gochman

Nat Commun· December 2017

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Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells.
Aaron Topol, Shijia Zhu, Brigham J Hartley, Jane English, Mads E Hauberg

Cell Rep· September 2017

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The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.
Yan Jiang, Yong-Hwee Eddie Loh, Prashanth Rajarajan, Teruyoshi Hirayama, Will Liao, Brigham J Hartley

Nat Genet· August 2017

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High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain.
Ting Zhou, Lei Tan, Gustav Y Cederquist, Yujie Fan, Brigham J Hartley

Cell Stem Cell· August 2017

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Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.
Seok-Man Ho, Brigham J Hartley, Erin Flaherty, Prashanth Rajarajan, Rawan Abdelaal

Stem Cell Reports· August 2017

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An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells.
Julia Tcw, Minghui Wang, Anna A Pimenova, Kathryn R Bowles, Brigham J Hartley

Stem Cell Reports· August 2017

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Neural organoids for disease phenotyping, drug screening and developmental biology studies.
Brigham J Hartley, Kristen J Brennand

Neurochem Int· June 2017

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Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells.
Seok-Man Ho, Brigham J Hartley, Julia Tcw, Michael Beaumont, Khalifa Stafford

Methods· May 2016

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Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells.
Aaron Topol, Shijia Zhu, Brigham J Hartley, Jane English, Mads E Hauberg

Cell Rep· May 2016

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Characterization of molecular and cellular phenotypes associated with a heterozygous deletion using patient-derived hiPSC neural cells.
Inkyu S Lee, Claudia M B Carvalho, Panagiotis Douvaras, Seok-Man Ho, Brigham J Hartley

NPJ Schizophr· June 2015

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Human pluripotent stem cell derived midbrain PITX3(eGFP/w) neurons: a versatile tool for pharmacological screening and neurodegenerative modeling.
Bradley Watmuff, Brigham J Hartley, Cameron P J Hunt, Stewart A Fabb, Colin W Pouton

Front Cell Neurosci· April 2015

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Zinc-finger nuclease enhanced gene targeting in human embryonic stem cells.
Brigham J Hartley, Stewart A Fabb, Ben A L Finnin, John M Haynes, Colin W Pouton

J Vis Exp· August 2014

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Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells.
Christian M Nefzger, Colin T Su, Stewart A Fabb, Brigham J Hartley, Siew J Beh

Stem Cells· July 2012

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Resolving the unconventional mechanisms underlying RXFP1 and RXFP2 receptor function.
Brigham J Hartley, Daniel J Scott, Gabrielle E Callander, Tracey N Wilkinson, Despina E Ganella

Ann N Y Acad Sci· April 2009

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