Publications by authors named "Brigitte Landesmann"

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Adverse Outcome Pathway (AOP) Coaching Program-how it functions and contributes to a more harmonized approach to AOP development and construction of AOP networks with regulatory utility.
Shihori Tanabe, Tanja Burgdorf, Judy Choi, Nathalie Delrue, Stephen W Edwards, Brigitte Landesmann

Environ Toxicol Chem· October 2025

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Report of the 3rd and 4th Mystery of Reactive Oxygen Species Conference.
Shihori Tanabe, Danielle Beaton, Vinita Chauhan, Ian Choi, Judy Choi, Brigitte Landesmann

ALTEX· October 2023

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Mechanistic Understanding of the Olfactory Neuroepithelium Involvement Leading to Short-Term Anosmia in COVID-19 Using the Adverse Outcome Pathway Framework.
Muhammad Ali Shahbaz, Francesca De Bernardi, Arto Alatalo, Magdalini Sachana, Laure-Alix Clerbaux, Brigitte Landesmann

Cells· September 2022

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Factors Modulating COVID-19: A Mechanistic Understanding Based on the Adverse Outcome Pathway Framework.
Laure-Alix Clerbaux, Maria Cristina Albertini, Núria Amigó, Anna Beronius, Gillina F G Bezemer, Brigitte Landesmann

J Clin Med· July 2022

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COVID-19 through Adverse Outcome Pathways: Building networks to better understand the disease - 3rd CIAO AOP Design Workshop.
Laure-Alix Clerbaux, Núria Amigó, Maria João Amorim, Anna Bal-Price, Sofia Batista Leite, Brigitte Landesmann

ALTEX· April 2022

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JRC Summer School on Non-animal Approaches in Science, May 2021.
Brigitte Landesmann, Alicia Paini

Altern Lab Anim· November 2021

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Systematic Organization of COVID-19 Data Supported by the Adverse Outcome Pathway Framework.
Penny Nymark, Magdalini Sachana, Sofia Batista Leite, Jukka Sund, Catharine E Krebs, Brigitte Landesmann

Front Public Health· June 2021

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Understanding COVID-19 through adverse outcome pathways - 2nd CIAO AOP Design Workshop.
Clemens Wittwehr, Maria João Amorim, Laure-Alix Clerbaux, Catharine Krebs, Brigitte Landesmann

ALTEX· April 2021

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Building and Applying Quantitative Adverse Outcome Pathway Models for Chemical Hazard and Risk Assessment.
Edward J Perkins, Roman Ashauer, Lyle Burgoon, Rory Conolly, Brigitte Landesmann

Environ Toxicol Chem· September 2019

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Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways.
Daniel L Villeneuve, Brigitte Landesmann, Paola Allavena, Noah Ashley, Anna Bal-Price

Toxicol Sci· June 2018

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Adverse outcome pathway development from protein alkylation to liver fibrosis.
Tomislav Horvat, Brigitte Landesmann, Alfonso Lostia, Mathieu Vinken, Sharon Munn

Arch Toxicol· April 2017

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Towards a 21st-century roadmap for biomedical research and drug discovery: consensus report and recommendations.
Gillian R Langley, Ian M Adcock, François Busquet, Kevin M Crofton, Elena Csernok, Brigitte Landesmann

Drug Discov Today· February 2017

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How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology.
Clemens Wittwehr, Hristo Aladjov, Gerald Ankley, Hugh J Byrne, Joop de Knecht, Brigitte Landesmann

Toxicol Sci· February 2017

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Sex differences in liver toxicity-do female and male human primary hepatocytes react differently to toxicants in vitro?
Milena Mennecozzi, Brigitte Landesmann, Taina Palosaari, Georgina Harris, Maurice Whelan

PLoS One· January 2016

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Building shared experience to advance practical application of pathway-based toxicology: liver toxicity mode-of-action.
Catherine Willett, Jessica Caverly Rae, Katy O Goyak, Gary Minsavage, Carl Westmoreland, Brigitte Landesmann

ALTEX· August 2015

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Pathway-based toxicity: history, current approaches and liver fibrosis and steatosis as prototypes.
Catherine Willett, Jessica Caverly Rae, Katy O Goyak, Brigitte Landesmann, Gary Minsavage

ALTEX· August 2015

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Putative adverse outcome pathways relevant to neurotoxicity.
Anna Bal-Price, Kevin M Crofton, Magdalini Sachana, Timothy J Shafer, Mamta Behl, Brigitte Landesmann

Crit Rev Toxicol· January 2015

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SEURAT-1 liver gold reference compounds: a mechanism-based review.
Paul Jennings, Michael Schwarz, Brigitte Landesmann, Silvia Maggioni, Marina Goumenou

Arch Toxicol· December 2014

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Adverse outcome pathway (AOP) development I: strategies and principles.
Daniel L Villeneuve, Doug Crump, Natàlia Garcia-Reyero, Markus Hecker, Thomas H Hutchinson, Brigitte Landesmann

Toxicol Sci· December 2014

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Adverse outcome pathway development II: best practices.
Daniel L Villeneuve, Doug Crump, Natàlia Garcia-Reyero, Markus Hecker, Thomas H Hutchinson, Brigitte Landesmann

Toxicol Sci· December 2014

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Adverse outcome pathway-based screening strategies for an animal-free safety assessment of chemicals.
Brigitte Landesmann, Milena Mennecozzi, Elisabet Berggren, Maurice Whelan

Altern Lab Anim· December 2013

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Development of an adverse outcome pathway from drug-mediated bile salt export pump inhibition to cholestatic liver injury.
Mathieu Vinken, Brigitte Landesmann, Marina Goumenou, Stefanie Vinken, Imran Shah

Toxicol Sci· November 2013

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