Publications by authors named "Brock Fletcher"

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Synthesis and characterization of chloroquine-modified albumin-binding siRNA-lipid conjugates for improved intracellular delivery and gene silencing in cancer cells.
Justin H Lo, Eva F Gbur, Nora Francini, Jinqi Ma, Alexander G Sorets, R Brock Fletcher

bioRxiv· October 2024

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Nonviral Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles.
R Brock Fletcher, Larry D Stokes, Isom B Kelly, Katelyn M Henderson, Isabel C Vallecillo-Viejo

ACS Nano· September 2023

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Core polymer optimization of ternary siRNA nanoparticles enhances in vivo safety, pharmacokinetics, and tumor gene silencing.
Shrusti S Patel, Ella N Hoogenboezem, Fang Yu, Carlisle R DeJulius, R Brock Fletcher

Biomaterials· June 2023

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Kupffer cell release of platelet activating factor drives dose limiting toxicities of nucleic acid nanocarriers.
Meredith A Jackson, Shrusti S Patel, Fang Yu, Matthew A Cottam, Evan B Glass, R Brock Fletcher

Biomaterials· January 2021

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Modifying Cell Membranes with Anionic Polymer Amphiphiles Potentiates Intracellular Delivery of Cationic Peptides.
Eric A Dailing, Kameron V Kilchrist, J William Tierney, R Brock Fletcher, Brian C Evans

ACS Appl Mater Interfaces· November 2020

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Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly Defined RIG-I Agonists.
Max E Jacobson, Kyle W Becker, Christian R Palmer, Lucinda E Pastora, R Brock Fletcher

ACS Cent Sci· November 2020

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Tuning Composition of Polymer and Porous Silicon Composite Nanoparticles for Early Endosome Escape of Anti-microRNA Peptide Nucleic Acids.
Isom B Kelly, R Brock Fletcher, James R McBride, Sharon M Weiss, Craig L Duvall

ACS Appl Mater Interfaces· September 2020

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Preparation, characterization and preliminary pharmacokinetic study of pH-sensitive Hydroxyapatite/Zein nano-drug delivery system for doxorubicin hydrochloride.
Liqiong Zha, Beilei Wang, Jiajia Qian, Brock Fletcher, Caiyun Zhang

J Pharm Pharmacol· April 2020

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An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles.
Brian C Evans, R Brock Fletcher, Kameron V Kilchrist, Eric A Dailing, Alvin J Mukalel

Nat Commun· November 2019

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Photoinitiated Polymerization of 4-Vinylpyridine on polyHIPE Foam Surface toward Improved Pu Separations.
Julia Pribyl, Brock Fletcher, Warren Steckle, Kathryn Taylor-Pashow, Thomas Shehee

Anal Chem· May 2017

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Genome sequence and phenotypic characterization of Caulobacter segnis.
Sagar Patel, Brock Fletcher, Derrick C Scott, Bert Ely

Curr Microbiol· March 2015

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