Publications by authors named "Brock Matter"

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Cysteamine-eluting contact lenses: integrating in vitro, in vivo, and in silico approaches for ocular drug delivery.
Anuj Chauhan, Sarbani Hazra, Brock Matter, Pankaj Kumar Sharma, Shilpa George

Int J Pharm· December 2025

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Hot-Melt Extrusion-Based Dexamethasone-PLGA Implants: Physicochemical, Physicomechanical, and Surface Morphological Properties and In Vitro Release Corrected for Drug Degradation.
Alireza Allen Ghaffari, Brock A Matter, Rachel R Hartman, David W A Bourne, Yan Wang

Pharmaceutics· July 2024

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The validation of new CHD1L inhibitors as a therapeutic strategy for cancer.
Sophia Clune, Paul Awolade, Qiong Zhou, Hector Esquer, Brock Matter

Biomed Pharmacother· January 2024

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Corneal Permeability and Uptake of Twenty-Five Drugs: Species Comparison and Quantitative Structure-Permeability Relationships.
Cleildo P Santana, Brock A Matter, Madhoosudan A Patil, Armando Silva-Cunha, Uday B Kompella

Pharmaceutics· June 2023

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A High-Throughput LC-MS/MS Method for the Simultaneous Quantification of Twenty-Seven Drug Molecules in Ocular Tissues.
Brock Matter, David W A Bourne, Uday B Kompella

AAPS PharmSciTech· July 2022

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Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L.
Brett J Prigaro, Hector Esquer, Qiong Zhou, Laura A Pike, Paul Awolade, Brock Matter

J Med Chem· March 2022

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The role of KCC2 in hyperexcitability of the neonatal brain.
Yogendra H Raol, Srdjan M Joksimovic, Dayalan Sampath, Brock A Matter, Philip M Lam

Neurosci Lett· November 2020

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Dexamethasone Degradation in Aqueous Medium and Implications for Correction of In Vitro Release from Sustained Release Delivery Systems.
Brock Matter, Alireza Ghaffari, David Bourne, Yan Wang, Stephanie Choi

AAPS PharmSciTech· October 2019

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Brain Distribution and Metabolism of Flupirtine, a Nonopioid Analgesic Drug with Antiseizure Effects, in Neonatal Rats.
Madhoosudan A Patil, Brock A Matter, Yogendra H Raol, David W A Bourne, Ryan A Kelley

Pharmaceutics· December 2018

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Mapping three guanine oxidation products along DNA following exposure to three types of reactive oxygen species.
Brock Matter, Christopher L Seiler, Kristopher Murphy, Xun Ming, Jianwei Zhao

Free Radic Biol Med· June 2018

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A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs.
Jeffrey Tran, Caroline Craven, Kathy Wabner, Jenn Schmit, Brock Matter

Invest Ophthalmol Vis Sci· July 2017

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High throughput HPLC-ESI(-)-MS/MS methodology for mercapturic acid metabolites of 1,3-butadiene: Biomarkers of exposure and bioactivation.
Srikanth Kotapati, Amanda Esades, Brock Matter, Chap Le, Natalia Tretyakova

Chem Biol Interact· November 2015

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Comparative metabolism of furan in rodent and human cryopreserved hepatocytes.
Leah A Gates, Martin B Phillips, Brock A Matter, Lisa A Peterson

Drug Metab Dispos· July 2014

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Mapping structurally defined guanine oxidation products along DNA duplexes: influence of local sequence context and endogenous cytosine methylation.
Xun Ming, Brock Matter, Matthew Song, Elizabeth Veliath, Ryan Shanley

J Am Chem Soc· March 2014

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Epicatechin-rich cocoa polyphenol inhibits Kras-activated pancreatic ductal carcinoma cell growth in vitro and in a mouse model.
Hifzur Rahman Siddique, D Joshua Liao, Shrawan Kumar Mishra, Todd Schuster, Lei Wang, Brock Matter

Int J Cancer· October 2012

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Quantitative analysis of trihydroxybutyl mercapturic acid, a urinary metabolite of 1,3-butadiene, in humans.
Srikanth Kotapati, Brock A Matter, Amy L Grant, Natalia Y Tretyakova

Chem Res Toxicol· September 2011

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Endogenous cytosine methylation and the formation of carcinogen carcinogen-DNA adducts.
Natalia Tretyakova, Rebecca Guza, Brock Matter

Nucleic Acids Symp Ser (Oxf)· November 2010

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Quantitative high-performance liquid chromatography-electrospray ionization tandem mass spectrometry analysis of bis-N7-guanine DNA-DNA cross-links in white blood cells of cancer patients receiving cyclophosphamide therapy.
Bhaskar Malayappan, L'aurelle Johnson, Bei Nie, Dolly Panchal, Brock Matter

Anal Chem· May 2010

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Sequence distribution of acetaldehyde-derived N2-ethyl-dG adducts along duplex DNA.
Brock Matter, Rebecca Guza, Jianwei Zhao, Zhong-ze Li, Roger Jones

Chem Res Toxicol· October 2007

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Spectral differentiation and immunoaffinity capillary electrophoresis separation of enantiomeric benzo(a)pyrene diol epoxide-derived DNA adducts.
Beata Miksa, Raja Chinnappan, Nhan C Dang, Mike Reppert, Brock Matter

Chem Res Toxicol· August 2007

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Quantitative analysis of the oxidative DNA lesion, 2,2-diamino-4-(2-deoxy-beta-D-erythro-pentofuranosyl)amino]-5(2H)-oxazolone (oxazolone), in vitro and in vivo by isotope dilution-capillary HPLC-ESI-MS/MS.
Brock Matter, Danuta Malejka-Giganti, A Saari Csallany, Natalia Tretyakova

Nucleic Acids Res· December 2006

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Identification of a cis-2-butene-1,4-dial-derived glutathione conjugate in the urine of furan-treated rats.
Lisa A Peterson, Meredith E Cummings, Jacqueline Y Chan, Choua C Vu, Brock A Matter

Chem Res Toxicol· September 2006

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Glutathione trapping to measure microsomal oxidation of furan to cis-2-butene-1,4-dial.
Lisa A Peterson, Meredith E Cummings, Choua C Vu, Brock A Matter

Drug Metab Dispos· October 2005

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Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.
Brock Matter, Gang Wang, Roger Jones, Natalia Tretyakova

Chem Res Toxicol· June 2004

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Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach.
Natalia Tretyakova, Brock Matter, Roger Jones, Anthony Shallop

Biochemistry· July 2002

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