Publications by authors named "Bronislaw Pytowski"

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Correction: Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human antihuman VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C.
Kris Persaud, Jean-Christophe Tille, Meilin Liu, Zhenping Zhu, Xenia Jimenez, Bronislaw Pytowski

J Cell Sci· September 2023

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Xerna™ TME Panel is a machine learning-based transcriptomic biomarker designed to predict therapeutic response in multiple cancers.
Mark Uhlik, Daniel Pointing, Seema Iyer, Luka Ausec, Miha Štajdohar, Bronislaw Pytowski

Front Oncol· May 2023

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Treatment with a VEGFR-2 antibody results in intra-tumor immune modulation and enhances anti-tumor efficacy of PD-L1 blockade in syngeneic murine tumor models.
Yanxia Li, Nelusha Amaladas, Marguerita O'Mahony, Jason R Manro, Ivan Inigo, Bronislaw Pytowski

PLoS One· July 2022

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Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy.
Caitlin D Lowery, Wayne Blosser, Michele Dowless, Matthew Renschler, Lisa V Perez, Bronislaw Pytowski

Oncotarget· September 2019

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Blockade of Vascular Endothelial Growth Factor Receptor-1 (Flt-1), Reveals a Novel Analgesic For Osteoarthritis-Induced Joint Pain.
Vaskar Das, Ranjan Kc, Xin Li, InSug O-Sullivan, Andre J van Wijnen, Bronislaw Pytowski

Gene Rep· June 2018

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VEGF-C promotes the development of lymphatics in bone and bone loss.
Devon Hominick, Asitha Silva, Noor Khurana, Ying Liu, Paul C Dechow, Bronislaw Pytowski

Elife· April 2018

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Phase 1 study of the anti-vascular endothelial growth factor receptor 3 monoclonal antibody LY3022856/IMC-3C5 in patients with advanced and refractory solid tumors and advanced colorectal cancer.
Muhammad Wasif Saif, James A Knost, E Gabriela Chiorean, Siva Rama Prasad Kambhampati, Danni Yu, Bronislaw Pytowski

Cancer Chemother Pharmacol· October 2016

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Antagonist antibodies to vascular endothelial growth factor receptor 2 (VEGFR-2) as anti-angiogenic agents.
Beverly L Falcon, Sudhakar Chintharlapalli, Mark T Uhlik, Bronislaw Pytowski

Pharmacol Ther· August 2016

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Stromal-Based Signatures for the Classification of Gastric Cancer.
Mark T Uhlik, Jiangang Liu, Beverly L Falcon, Seema Iyer, Julie Stewart, Bronislaw Pytowski

Cancer Res· May 2016

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Inhibition of VEGFR-3 activation in tumor-draining lymph nodes suppresses the outgrowth of lymph node metastases in the MT-450 syngeneic rat breast cancer model.
Luca Quagliata, Sandra Klusmeier, Natascha Cremers, Bronislaw Pytowski, Alfred Harvey

Clin Exp Metastasis· March 2014

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Pulmonary lymphangiectasia resulting from vascular endothelial growth factor-C overexpression during a critical period.
Li-Chin Yao, Chiara Testini, Denis Tvorogov, Andrey Anisimov, Sara O Vargas, Bronislaw Pytowski

Circ Res· February 2014

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Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling.
Rui Benedito, Susana F Rocha, Marina Woeste, Martin Zamykal, Freddy Radtke, Bronislaw Pytowski

Nature· March 2012

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Live imaging of newly formed lymphatic vessels in the cornea.
Don Yuen, Xiufeng Wu, Alex C Kwan, Jeffrey Ledue, Hui Zhang, Bronislaw Pytowski

Cell Res· December 2011

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Vascular endothelial growth factor receptor 3 directly regulates murine neurogenesis.
Charles-Félix Calvo, Romain H Fontaine, Jihane Soueid, Tuomas Tammela, Taija Makinen, Bronislaw Pytowski

Genes Dev· April 2011

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Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation.
Reto Huggenberger, Stefan Ullmann, Steven T Proulx, Bronislaw Pytowski, Kari Alitalo

J Exp Med· September 2010

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VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts.
Ingrid Nilsson, Fuad Bahram, Xiujuan Li, Laura Gualandi, Sina Koch, Bronislaw Pytowski

EMBO J· April 2010

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Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.
Antti I Nykänen, Henrik Sandelin, Rainer Krebs, Mikko A I Keränen, Raimo Tuuminen, Bronislaw Pytowski

Circulation· March 2010

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Vascular endothelial growth factor receptor-1 in human cancer: concise review and rationale for development of IMC-18F1 (Human antibody targeting vascular endothelial growth factor receptor-1).
Jonathan D Schwartz, Eric K Rowinsky, Hagop Youssoufian, Bronislaw Pytowski, Yan Wu

Cancer· February 2010

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Inhibition of lymphangiogenesis and lymphatic drainage via vascular endothelial growth factor receptor 3 blockade increases the severity of inflammation in a mouse model of chronic inflammatory arthritis.
Ruolin Guo, Quan Zhou, Steven T Proulx, Ronald Wood, Rui-Cheng Ji, Bronislaw Pytowski

Arthritis Rheum· September 2009

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Vascular endothelial growth factor receptor 2 (VEGFR-2) functions to promote uterine decidual angiogenesis during early pregnancy in the mouse.
Nataki C Douglas, Hongyan Tang, Raul Gomez, Bronislaw Pytowski, Daniel J Hicklin

Endocrinology· August 2009

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Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells.
Andrea T Hooper, Jason M Butler, Daniel J Nolan, Andrea Kranz, Kaoruko Iida, Bronislaw Pytowski

Cell Stem Cell· March 2009

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Anti-VEGF agents confer survival advantages to tumor-bearing mice by improving cancer-associated systemic syndrome.
Yuan Xue, Piotr Religa, Renhai Cao, Anker Jon Hansen, Franco Lucchini, Bronislaw Pytowski

Proc Natl Acad Sci U S A· November 2008

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Suppression of prostate cancer nodal and systemic metastasis by blockade of the lymphangiogenic axis.
Jeremy B Burton, Saul J Priceman, James L Sung, Ebba Brakenhielm, Dong Sung An, Bronislaw Pytowski

Cancer Res· October 2008

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Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation.
Tuomas Tammela, Georgia Zarkada, Elisabet Wallgard, Aino Murtomäki, Steven Suchting, Bronislaw Pytowski

Nature· July 2008

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VEGFR-3 expression is restricted to blood and lymphatic vessels in solid tumors.
Tatiana V Petrova, Petri Bono, Wolfgang Holnthoner, Jessica Chesnes, Bronislaw Pytowski

Cancer Cell· June 2008

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