Publications by authors named "Bruce D Pascal"

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A ternary switch model governing ERα ligand binding domain conformation.
Daniel P McDougal, Jordan L Pederick, Scott J Novick, Blagojce Jovcevski, Annmaree K Warrender, Bruce D Pascal

Nat Commun· November 2025

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HXMS: a standardized file format for HX/MS data.
Kyle C Weber, Chenlin Lu, Roberto Vera Alvarez, Bruce D Pascal, Anum Glasgow

bioRxiv· October 2025

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Structural proteomics defines a sequential priming mechanism for the progesterone receptor.
Matthew D Mann, Min Wang, Josephine C Ferreon, Phoebe S Tsoi, Michael P Suess, Bruce D Pascal

Nat Commun· May 2025

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Structural proteomics defines a sequential priming mechanism for the progesterone receptor.
Matthew D Mann, Min Wang, Josephine C Ferreon, Michael P Suess, Antrix Jain, Bruce D Pascal

bioRxiv· October 2024

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The intrinsically disordered CARDs-Helicase linker in RIG-I is a molecular gate for RNA proofreading.
Brandon D Schweibenz, Swapnil C Devarkar, Mihai Solotchi, Candice Craig, Jie Zheng, Bruce D Pascal

EMBO J· May 2022

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Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Bin Song, Yun Chen, Xin Liu, Fei Yuan, Eddie Yong Jun Tan, Bruce D Pascal

Immunity· October 2021

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Dual-mechanism estrogen receptor inhibitors.
Jian Min, Jerome C Nwachukwu, Charles K Min, Jacqline W Njeri, Sathish Srinivasan, Bruce D Pascal

Proc Natl Acad Sci U S A· August 2021

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Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions.
Jie Zheng, Timothy S Strutzenberg, Adrian Reich, Venkatasubramanian Dharmarajan, Bruce D Pascal

Anal Chem· August 2020

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Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer.
Steve Tuske, Jie Zheng, Erik D Olson, Francesc X Ruiz, Bruce D Pascal

Curr Res Struct Biol· June 2020

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A Decoupled Automation Platform for Hydrogen/Deuterium Exchange Mass Spectrometry Experiments.
Alfonso Espada, Ruben Haro, Jesus Castañon, Cristina Sayago, Francisco Perez-Cozar, Bruce D Pascal

J Am Soc Mass Spectrom· December 2019

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Protein dynamics and conformational changes explored by hydrogen/deuterium exchange mass spectrometry.
Jie Zheng, Timothy Strutzenberg, Bruce D Pascal, Patrick R Griffin

Curr Opin Struct Biol· October 2019

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Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.
Glenn R Masson, John E Burke, Natalie G Ahn, Ganesh S Anand, Christoph Borchers, Bruce D Pascal

Nat Methods· July 2019

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Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.
Hyeonwoo Kim, Christiane D Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Bruce D Pascal

Cell· July 2019

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Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex.
Dipak N Patil, Erumbi S Rangarajan, Scott J Novick, Bruce D Pascal, Douglas J Kojetin

Elife· December 2018

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Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.
Hyeonwoo Kim, Christiane D Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Bruce D Pascal

Cell· December 2018

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HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity.
Jie Zheng, Chen Wang, Mi Ra Chang, Swapnil C Devarkar, Brandon Schweibenz, Bruce D Pascal

Nat Commun· December 2018

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Long noncoding RNA GM12371 acts as a transcriptional regulator of synapse function.
Bindu L Raveendra, Supriya Swarnkar, Yosef Avchalumov, Xin-An Liu, Eddie Grinman, Bruce D Pascal

Proc Natl Acad Sci U S A· October 2018

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Structural and Dynamic Elucidation of a Non-acid PPAR Partial Agonist: SR1988.
Rebecca L Frkic, Benjamin S Chua, Youseung Shin, Bruce D Pascal, Scott J Novick

Nucl Receptor Res· January 2018

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Nucleotide Binding to ARL2 in the TBCD∙ARL2∙β-Tubulin Complex Drives Conformational Changes in β-Tubulin.
Joshua W Francis, Devrishi Goswami, Scott J Novick, Bruce D Pascal, Emily R Weikum

J Mol Biol· November 2017

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HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions.
Jie Zheng, Mi Ra Chang, Ryan E Stites, Yong Wang, John B Bruning, Bruce D Pascal

Nat Commun· October 2017

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A Residue-Resolved Bayesian Approach to Quantitative Interpretation of Hydrogen-Deuterium Exchange from Mass Spectrometry: Application to Characterizing Protein-Ligand Interactions.
Daniel J Saltzberg, Howard B Broughton, Riccardo Pellarin, Michael J Chalmers, Alfonso Espada, Bruce D Pascal

J Phys Chem B· April 2017

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Two-Site Evaluation of the Repeatability and Precision of an Automated Dual-Column Hydrogen/Deuterium Exchange Mass Spectrometry Platform.
David J Cummins, Alfonso Espada, Scott J Novick, Manuel Molina-Martin, Ryan E Stites, Bruce D Pascal

Anal Chem· June 2016

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Software Analysis of Uncorrelated MS1 Peaks for Discovery of Post-Translational Modifications.
Bruce D Pascal, Graham M West, Catherina Scharager-Tapia, Ricardo Flefil, Tina Moroni

J Am Soc Mass Spectrom· December 2015

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SERBP1 Is a Component of the Liver Receptor Homologue-1 Transcriptional Complex.
Yelenis Mari, Graham M West, Catherina Scharager-Tapia, Bruce D Pascal, Ruben D Garcia-Ordonez

J Proteome Res· November 2015

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Identification of Bexarotene as a PPARγ Antagonist with HDX.
David P Marciano, Dana S Kuruvilla, Bruce D Pascal, Patrick R Griffin

PPAR Res· October 2015

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