Publications by authors named "Bruce Gerlitz"

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Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes.
Thati Madhusudhan, Hongjie Wang, Beate K Straub, Elisabeth Gröne, Qianxing Zhou, Bruce Gerlitz

Blood· January 2012

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Recombinant activated protein C attenuates coagulopathy and inflammation when administered early in murine pneumococcal pneumonia.
Marcel Schouten, Cornelis van 't Veer, Joris J T H Roelofs, Bruce Gerlitz, Brian W Grinnell

Thromb Haemost· December 2011

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Activated protein C ameliorates coagulopathy but does not influence outcome in lethal H1N1 influenza: a controlled laboratory study.
Marcel Schouten, Koenraad F van der Sluijs, Bruce Gerlitz, Brian W Grinnell, Joris J T H Roelofs

Crit Care· November 2010

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Therapeutic recombinant murine activated protein C attenuates pulmonary coagulopathy and improves survival in murine pneumococcal pneumonia.
Marcel Schouten, Cornelis van 't Veer, Florry E van den Boogaard, Bruce Gerlitz, Brian W Grinnell

J Infect Dis· November 2010

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Distinct functions of activated protein C differentially attenuate acute kidney injury.
Akanksha Gupta, Bruce Gerlitz, Mark A Richardson, Christopher Bull, David T Berg

J Am Soc Nephrol· February 2009

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Treatment of sepsis-induced acquired protein C deficiency reverses Angiotensin-converting enzyme-2 inhibition and decreases pulmonary inflammatory response.
Mark A Richardson, Akanksha Gupta, Lee A O'Brien, David T Berg, Bruce Gerlitz

J Pharmacol Exp Ther· April 2008

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Activated protein C modulates chemokine response and tissue injury in experimental sepsis.
Ganesh R Sharma, Bruce Gerlitz, David T Berg, Martin S Cramer, Joseph A Jakubowski

Adv Exp Med Biol· April 2008

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Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets.
May H Han, Sun-Il Hwang, Dolly B Roy, Deborah H Lundgren, Jordan V Price, Bruce Gerlitz

Nature· February 2008

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Study of plasma protein C and inflammatory pathways: biomarkers for dimethylnitrosamine-induced liver fibrosis in rats.
Joy K Saha, Jinqi Xia, George E Sandusky, Yun-Fei Chen, Bruce Gerlitz

Eur J Pharmacol· December 2007

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Activated protein C decreases tumor necrosis factor related apoptosis-inducing ligand by an EPCR- independent mechanism involving Egr-1/Erk-1/2 activation.
Lee A O'Brien, Mark A Richardson, Sean F Mehrbod, David T Berg, Bruce Gerlitz

Arterioscler Thromb Vasc Biol· December 2007

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Activated protein C protects against diabetic nephropathy by inhibiting endothelial and podocyte apoptosis.
Berend Isermann, Ilya A Vinnikov, Thati Madhusudhan, Stefanie Herzog, Muhammed Kashif, Bruce Gerlitz

Nat Med· November 2007

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Activated protein C suppresses adrenomedullin and ameliorates lipopolysaccharide-induced hypotension.
Akanksha Gupta, David T Berg, Bruce Gerlitz, Mark A Richardson, Elizabeth Galbreath

Shock· October 2007

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Polymeric coatings that mimic the endothelium: combining nitric oxide release with surface-bound active thrombomodulin and heparin.
Biyun Wu, Bruce Gerlitz, Brian W Grinnell, Mark E Meyerhoff

Biomaterials· October 2007

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Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2.
Akanksha Gupta, George J Rhodes, David T Berg, Bruce Gerlitz, Bruce A Molitoris

Am J Physiol Renal Physiol· July 2007

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Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
Franco Scaldaferri, Miquel Sans, Stefania Vetrano, Cristina Graziani, Raimondo De Cristofaro, Bruce Gerlitz

J Clin Invest· July 2007

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Role of protein C in renal dysfunction after polymicrobial sepsis.
Akanksha Gupta, David T Berg, Bruce Gerlitz, Ganesh R Sharma, Samreen Syed

J Am Soc Nephrol· March 2007

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FoxA2 involvement in suppression of protein C, an outcome predictor in experimental sepsis.
David T Berg, Bruce Gerlitz, Ganesh R Sharma, Mark A Richardson, Eddie J Stephens

Clin Vaccine Immunol· March 2006

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Evaluation of protein C and other biomarkers as predictors of mortality in a rat cecal ligation and puncture model of sepsis.
Josef G Heuer, Ganesh R Sharma, Bruce Gerlitz, Tonghai Zhang, Dianna L Bailey

Crit Care Med· July 2004

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Basic residues in the 37-loop of activated protein C modulate inhibition by protein C inhibitor but not by alpha(1)-antitrypsin.
Laura N Glasscock, Bruce Gerlitz, Scott T Cooper, Brian W Grinnell, Frank C Church

Biochim Biophys Acta· June 2003

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Engineering the proteolytic specificity of activated protein C improves its pharmacological properties.
David T Berg, Bruce Gerlitz, Jing Shang, Tommy Smith, Paula Santa

Proc Natl Acad Sci U S A· April 2003

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