Publications by authors named "Joseph A Jakubowski"

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Clopidogrel-Mediated P2Y Inhibition According to Renal Function in Patients With Diabetes Mellitus and CAD.
Luis Ortega-Paz, Francesco Franchi, Fabiana Rollini, Mattia Galli, Latonya Been, Joseph A Jakubowski

JACC Basic Transl Sci· July 2024

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Circulating MicroRNA Profiling in Non-ST Elevated Coronary Artery Syndrome Highlights Genomic Associations with Serial Platelet Reactivity Measurements.
Kristian C Becker, Lydia Coulter Kwee, Megan L Neely, Elizabeth Grass, Joseph A Jakubowski

Sci Rep· April 2020

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Geographic Differences in Phenotype and Treatment of Children with Sickle Cell Anemia from the Multinational DOVE Study.
Baba Psalm Duniya Inusa, Raffaella Colombatti, David C Rees, Matthew M Heeney, Carolyn C Hoppe, Joseph A Jakubowski

J Clin Med· November 2019

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Novel findings from the multinational DOVE study on geographic and age-related differences in pain perception and analgesic usage in children with sickle cell anaemia.
Julie Kanter, Lori E Heath, Jack Knorr, E Tsiri Agbenyega, Raffaella Colombatti, Joseph A Jakubowski

Br J Haematol· March 2019

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Population Pharmacokinetic and Exposure-Response Analyses of Prasugrel in Pediatric Patients with Sickle Cell Anemia.
Brian A Moser, Elizabeth S LaBell, Emmanuel Chigutsa, Joseph A Jakubowski, David S Small

Clin Pharmacokinet· February 2018

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Successful utilization of an electronic pain diary in a multinational phase 3 interventional study of pediatric sickle cell anemia.
Lori E Heath, Matthew M Heeney, Carolyn C Hoppe, Samuel Adjei, Tsiri Agbenyega, Joseph A Jakubowski

Clin Trials· December 2017

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Calpain-1 regulates platelet function in a humanized mouse model of sickle cell disease.
Jennifer O Nwankwo, Thomas Gremmel, Anja J Gerrits, Farha J Mithila, Rod R Warburton, Joseph A Jakubowski

Thromb Res· December 2017

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Temporal Biomarker Profiling Reveals Longitudinal Changes in Risk of Death or Myocardial Infarction in Non-ST-Segment Elevation Acute Coronary Syndrome.
Mark Y Chan, Megan L Neely, Matthew T Roe, Shaun G Goodman, David Erlinge, Joseph A Jakubowski

Clin Chem· July 2017

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A Novel Model of Intravital Platelet Imaging Using CD41-ZsGreen1 Transgenic Rats.
Makoto Mizuno, Atsuyuki Tomizawa, Kousaku Ohno, Joseph A Jakubowski, Atsuhiro Sugidachi

PLoS One· April 2017

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The Rationale for and Clinical Pharmacology of Prasugrel 5 mg.
Joseph A Jakubowski, David Erlinge, Dimitrios Alexopoulos, David S Small, Kenneth J Winters

Am J Cardiovasc Drugs· April 2017

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Real-time dose adjustment using point-of-care platelet reactivity testing in a double-blind study of prasugrel in children with sickle cell anaemia.
Joseph A Jakubowski, Carolyn C Hoppe, Chunmei Zhou, Brendan E Smith, Patricia B Brown

Thromb Haemost· February 2017

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Impact of chronic kidney disease on platelet P2Y receptor signalling in patients with type 2 diabetes mellitus.
Lydia R Engwenyu, Francesco Franchi, Fabiana Rollini, Jung Rae Cho, Christopher DeGroat, Joseph A Jakubowski

Thromb Haemost· January 2017

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Cangrelor inhibits the binding of the active metabolites of clopidogrel and prasugrel to P2Y12 receptors in vitro.
Heather M Judge, Robert J Buckland, Joseph A Jakubowski, Robert F Storey

Platelets· December 2016

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Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.
Jan H Cornel, E Magnus Ohman, Benjamin Neely, Joseph A Jakubowski, Deepak L Bhatt

J Am Heart Assoc· November 2016

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Prasugrel 5 mg inhibits platelet P-selectin and GPIIb-IIIa expression in very elderly and non elderly: results from the GENERATIONS trial, a pharmacodynamic study in stable CAD patients.
Henrik Wagner, Christian Lood, Catharina Borna, Olof Gidlöf, Lennart Truedsson, Joseph A Jakubowski

J Thromb Thrombolysis· October 2016

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The active metabolite of prasugrel, R-138727, improves cerebral blood flow and reduces cerebral infarction and neurologic deficits in a non-human primate model of acute ischaemic stroke.
Atsuhiro Sugidachi, Makoto Mizuno, Kousaku Ohno, Joseph A Jakubowski, Atsuyuki Tomizawa

Eur J Pharmacol· October 2016

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Prasugrel, a Platelet P2Y12 Receptor Antagonist, Improves Abnormal Gait in a Novel Murine Model of Thrombotic Hindlimb Ischemia.
Kousaku Ohno, Atsuyuki Tomizawa, Makoto Mizuno, Joseph A Jakubowski, Atsuhiro Sugidachi

J Am Heart Assoc· April 2016

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Impact of CYP2C19 Metabolizer Status on Patients With ACS Treated With Prasugrel Versus Clopidogrel.
Jacob A Doll, Megan L Neely, Matthew T Roe, Paul W Armstrong, Harvey D White, Joseph A Jakubowski

J Am Coll Cardiol· March 2016

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Design of the DOVE (Determining Effects of Platelet Inhibition on Vaso-Occlusive Events) trial: A global Phase 3 double-blind, randomized, placebo-controlled, multicenter study of the efficacy and safety of prasugrel in pediatric patients with sickle cell anemia utilizing a dose titration strategy.
Carolyn C Hoppe, Lori Styles, Lori E Heath, Chunmei Zhou, Joseph A Jakubowski

Pediatr Blood Cancer· February 2016

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A Multinational Trial of Prasugrel for Sickle Cell Vaso-Occlusive Events.
Matthew M Heeney, Carolyn C Hoppe, Miguel R Abboud, Baba Inusa, Julie Kanter, Joseph A Jakubowski

N Engl J Med· February 2016

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Prasugrel reduces ischaemic infarct volume and ameliorates neurological deficits in a non-human primate model of middle cerebral artery thrombosis.
Atsuyuki Tomizawa, Kousaku Ohno, Joseph A Jakubowski, Makoto Mizuno, Atsuhiro Sugidachi

Thromb Res· December 2015

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Prevention of occlusive arterial thrombus formation by a single loading dose of prasugrel suppresses neointimal hyperplasia in mice.
Kousaku Ohno, Atsuyuki Tomizawa, Joseph A Jakubowski, Makoto Mizuno, Atsuhiro Sugidachi

Thromb Res· December 2015

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Characterization of platelet aggregation responses in microminipigs: Comparison with miniature pigs and the influence of dual antiplatelet administration of aspirin plus prasugrel.
Kousaku Ohno, Atsuyuki Tomizawa, Joseph A Jakubowski, Makoto Mizuno, Atsuhiro Sugidachi

Thromb Res· May 2015

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Reply: elevated serum fibrinogen: an independent link between diabetes mellitus, impaired on-clopidogrel platelet inhibition, and major adverse cardiac events after percutaneous coronary intervention.
Dominick J Angiolillo, Joseph A Jakubowski, Francesco Franchi, Fabiana Rollini, Theodore A Bass

J Am Coll Cardiol· April 2015

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Point-of-care platelet reactivity determination with VerifyNow-P2Y12 following administration of clopidogrel or prasugrel: data from a real-world, clinical care inpatient setting.
Jay P Bae, Sean D Candrilli, Jamie Fortenberry, Juliana L Meyers, Joseph A Jakubowski

Hosp Pract (1995)· October 2014

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