Publications by authors named "David S Small"

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Population Pharmacokinetic and Exposure-Response Analyses of Prasugrel in Pediatric Patients with Sickle Cell Anemia.
Brian A Moser, Elizabeth S LaBell, Emmanuel Chigutsa, Joseph A Jakubowski, David S Small

Clin Pharmacokinet· February 2018

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The Rationale for and Clinical Pharmacology of Prasugrel 5 mg.
Joseph A Jakubowski, David Erlinge, Dimitrios Alexopoulos, David S Small, Kenneth J Winters

Am J Cardiovasc Drugs· April 2017

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Real-time dose adjustment using point-of-care platelet reactivity testing in a double-blind study of prasugrel in children with sickle cell anaemia.
Joseph A Jakubowski, Carolyn C Hoppe, Chunmei Zhou, Brendan E Smith, Patricia B Brown, David S Small

Thromb Haemost· February 2017

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Impact of Increased Gastric pH on the Pharmacokinetics of Evacetrapib in Healthy Subjects.
David S Small, Jane Royalty, Ellen A Cannady, Christine Hale, Ming-Dauh Wang

Pharmacotherapy· July 2016

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Absolute bioavailability of evacetrapib in healthy subjects determined by simultaneous administration of oral evacetrapib and intravenous [(13) C8 ]-evacetrapib as a tracer.
Ellen A Cannady, Aktham Aburub, Chris Ward, Chris Hinds, Boris Czeskis, David S Small

J Labelled Comp Radiopharm· May 2016

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Effect of hepatic or renal impairment on the pharmacokinetics of evacetrapib.
David S Small, Wei Zhang, Jane Royalty, Ellen A Cannady, Delyn Downs

Eur J Clin Pharmacol· May 2016

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Amount of Testosterone on Laundered Clothing After Use of Testosterone Topical 2% Solution by Healthy Male Volunteers.
Darlene K Satonin, Xiao Ni, Malcolm I Mitchell, Hellen Joly, David Muram, David S Small

J Sex Med· February 2016

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Evacetrapib: in vitro and clinical disposition, metabolism, excretion, and assessment of drug interaction potential with strong CYP3A and CYP2C8 inhibitors.
Ellen A Cannady, Ming-Dauh Wang, Stuart Friedrich, Jessica L F Rehmel, Ping Yi, David S Small

Pharmacol Res Perspect· October 2015

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A Multidose Study to Examine the Effect of Food on Evacetrapib Exposure at Steady State.
David S Small, Wei Zhang, Jane Royalty, Ellen A Cannady, Delyn Downs

J Cardiovasc Pharmacol Ther· September 2015

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Assessment of the persistence of anacetrapib and evacetrapib concentrations using two pharmacokinetic modeling approaches.
David S Small, Alice Ban Ke, Stephen D Hall, Nathan Mantlo, Matthew Rotelli

J Clin Pharmacol· July 2015

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Higher body weight patients on clopidogrel maintenance therapy have lower active metabolite concentrations, lower levels of platelet inhibition, and higher rates of poor responders than low body weight patients.
Henrik Wagner, Dominick J Angiolillo, Jurrien M Ten Berg, Thomas O Bergmeijer, Joseph A Jakubowski, David S Small

J Thromb Thrombolysis· February 2015

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Prasugrel in children with sickle cell disease: pharmacokinetic and pharmacodynamic data from an open-label, adaptive-design, dose-ranging study.
Lori Styles, Darell Heiselman, Lori E Heath, Brian A Moser, David S Small

J Pediatr Hematol Oncol· January 2015

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Effect of deodorant and antiperspirant use and presence or absence of axillary hair on absorption of testosterone 2% solution applied to men's axillae.
David S Small, Xiao Ni, Paula Polzer, Richard Vart, Darlene K Satonin

J Sex Med· November 2014

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The influence of body size on the pharmacodynamic and pharmacokinetic response to clopidogrel and prasugrel: a retrospective analysis of the FEATHER study.
Joseph A Jakubowski, Dominick J Angiolillo, Chunmei Zhou, David S Small, Brian A Moser

Thromb Res· September 2014

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Steady-state pharmacokinetics of darunavir/ritonavir and pitavastatin when co-administered to healthy adult volunteers.
Christine Y Yu, Stuart E Campbell, Craig A Sponseller, David S Small, Matthew M Medlock

Clin Drug Investig· July 2014

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Prasugrel 5 mg in the very elderly attenuates platelet inhibition but maintains noninferiority to prasugrel 10 mg in nonelderly patients: the GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients.
David Erlinge, Paul A Gurbel, Stefan James, Tomas L Lindahl, Peter Svensson, David S Small

J Am Coll Cardiol· August 2013

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Pharmacokinetic and pharmacodynamic effects of prasugrel in healthy Korean males.
Kyung-Sang Yu, Kyung Woo Park, Ronan P Kelly, Namyi Gu, Christopher Payne, David S Small

J Cardiovasc Pharmacol· July 2013

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A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity.
Joseph A Jakubowski, Chunmei Zhou, David S Small, Kenneth J Winters, D Richard Lachno

Br J Clin Pharmacol· June 2013

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Reduction in platelet reactivity with prasugrel 5 mg in low-body-weight patients is noninferior to prasugrel 10 mg in higher-body-weight patients: results from the FEATHER trial.
David Erlinge, Jurrien Ten Berg, David Foley, Dominick J Angiolillo, Henrik Wagner, David S Small

J Am Coll Cardiol· November 2012

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Relationship between exposure to prasugrel active metabolite and clinical outcomes in the TRITON-TIMI 38 substudy.
Jeffrey S Riesmeyer, Daniel E Salazar, Govinda J Weerakkody, Lan Ni, Rebecca E Wrishko, David S Small

J Clin Pharmacol· June 2012

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Effect of pitavastatin vs. rosuvastatin on international normalized ratio in healthy volunteers on steady-state warfarin.
Christine Y Yu, Stuart E Campbell, Baojin Zhu, Mary Pat Knadler, David S Small

Curr Med Res Opin· February 2012

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Pharmacokinetics and pharmacodynamics following maintenance doses of prasugrel and clopidogrel in Chinese carriers of CYP2C19 variants.
Ronan P Kelly, Sandra L Close, Nagy A Farid, Kenneth J Winters, Lei Shen, David S Small

Br J Clin Pharmacol· January 2012

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Absence of "rebound" platelet hyperreactivity following cessation of prasugrel.
Joseph A Jakubowski, Ying G Li, Christopher D Payne, David S Small, Kenneth J Winters

Thromb Haemost· July 2011

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The onset of inhibition of platelet aggregation with prasugrel compared with clopidogrel loading doses using gatekeeping analysis of integrated clinical pharmacology data.
Baojin Zhu, Mark B Effron, M Pandurang Kulkarni, Ying G Li, Joseph A Jakubowski, David S Small

J Cardiovasc Pharmacol· March 2011

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Effect of intrinsic and extrinsic factors on the clinical pharmacokinetics and pharmacodynamics of prasugrel.
David S Small, Nagy A Farid, Christopher D Payne, Christopher S Konkoy, Joseph A Jakubowski

Clin Pharmacokinet· December 2010

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