Publications by authors named "Bryan Lemon"

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HPN328, a Trispecific T Cell-Activating Protein Construct Targeting DLL3-Expressing Solid Tumors.
Mary E Molloy, Wade H Aaron, Manasi Barath, Mabel C Bush, Evan C Callihan, Bryan D Lemon

Mol Cancer Ther· September 2024

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Preclinical Characterization of HPN536, a Trispecific, T-Cell-Activating Protein Construct for the Treatment of Mesothelin-Expressing Solid Tumors.
Mary Ellen Molloy, Richard J Austin, Bryan D Lemon, Wade H Aaron, Vaishnavi Ganti

Clin Cancer Res· March 2021

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TriTACs, a Novel Class of T-Cell-Engaging Protein Constructs Designed for the Treatment of Solid Tumors.
Richard J Austin, Bryan D Lemon, Wade H Aaron, Manasi Barath, Patricia A Culp

Mol Cancer Ther· January 2021

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Soluble CLEC2 Extracellular Domain Improves Glucose and Lipid Homeostasis by Regulating Liver Kupffer Cell Polarization.
Xinle Wu, Jun Zhang, Hongfei Ge, Jamila Gupte, Helene Baribault, Bryan Lemon

EBioMedicine· March 2015

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Dual actions of fibroblast growth factor 19 on lipid metabolism.
Xinle Wu, Hongfei Ge, Hélène Baribault, Jamila Gupte, Jennifer Weiszmann, Bryan Lemon

J Lipid Res· February 2013

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Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism.
Hongfei Ge, Helene Baribault, Steven Vonderfecht, Bryan Lemon, Jennifer Weiszmann

PLoS One· August 2012

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Crystal structure of a single-chain trimer of human adiponectin globular domain.
Xiaoshan Min, Bryan Lemon, Jie Tang, Qiang Liu, Richard Zhang

FEBS Lett· March 2012

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Discovery of potent and specific CXCR3 antagonists.
Xiaoqi Chen, Jeff Mihalic, Jeff Deignan, Darin J Gustin, Jason Duquette, Bryan Lemon

Bioorg Med Chem Lett· January 2012

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The FGFR D3 domain determines receptor selectivity for fibroblast growth factor 21.
Jamila Gupte, Li Yang, Xinle Wu, Jennifer Weiszmann, Randy Hecht, Bryan Lemon

J Mol Biol· May 2011

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Separating mitogenic and metabolic activities of fibroblast growth factor 19 (FGF19).
Xinle Wu, Hongfei Ge, Bryan Lemon, Steven Vonderfecht, Helene Baribault

Proc Natl Acad Sci U S A· August 2010

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Generation of novel long-acting globular adiponectin molecules.
Hongfei Ge, Yumei Xiong, Bryan Lemon, Ki Jeong Lee, Jay Tang

J Mol Biol· May 2010

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FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation.
Xinle Wu, Hongfei Ge, Bryan Lemon, Steven Vonderfecht, Jennifer Weiszmann

J Biol Chem· February 2010

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Imidazo-pyrazine derivatives as potent CXCR3 antagonists.
Xiaohui Du, Darin J Gustin, Xiaoqi Chen, Jason Duquette, Lawrence R McGee, Bryan Lemon

Bioorg Med Chem Lett· September 2009

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Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice.
Xinle Wu, Hongfei Ge, Bryan Lemon, Jennifer Weiszmann, Jamila Gupte

Proc Natl Acad Sci U S A· August 2009

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C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors.
Xinle Wu, Bryan Lemon, XiaoFan Li, Jamila Gupte, Jennifer Weiszmann

J Biol Chem· November 2008

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Optimization of the heterocyclic core of the quinazolinone-derived CXCR3 antagonists.
An-Rong Li, Michael G Johnson, Jiwen Liu, Xiaoqi Chen, Xiaohui Du, Bryan Lemon

Bioorg Med Chem Lett· January 2008

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Design and optimization of imidazole derivatives as potent CXCR3 antagonists.
Xiaohui Du, Xiaoqi Chen, Jeffrey T Mihalic, Jeffrey Deignan, Jason Duquette, Bryan Lemon

Bioorg Med Chem Lett· January 2008

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Co-receptor requirements for fibroblast growth factor-19 signaling.
Xinle Wu, Hongfei Ge, Jamila Gupte, Jennifer Weiszmann, Grant Shimamoto, Bryan Lemon

J Biol Chem· October 2007

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Structural studies of the human PBAF chromatin-remodeling complex.
Andres E Leschziner, Bryan Lemon, Robert Tjian, Eva Nogales

Structure· February 2005

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