Publications by authors named "Bryce Chackerian"

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Immunization with VLP-based vaccines induces high IgG antibody titers in dermal interstitial fluid.
Alexandra Francian, Srinivasa R Gadam, Aidan Leyba, Robert M Taylor, Pavan Muttil, Bryce Chackerian

NPJ Vaccines· October 2025

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Formulation, Characterization, and In Vivo Immunogenicity of Heat-Stabilized Dissolvable Microneedles Containing a Novel VLP Vaccine.
Aidan Leyba, Alexandra Francian, Mohammad Razjmoo, Amelia Bierle, Ranjith Janardhana, Bryce Chackerian

Pharm Res· September 2025

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Virus-like particle vaccines targeting a key epitope in circumsporozoite protein provide sterilizing immunity against malaria.
Yogesh Nepal, Alexandra Francian, Yevel Flores-Garcia, Bryce T Roberts, Sunil A David, Bryce Chackerian

NPJ Vaccines· July 2025

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Multi-phase Training in Virus-Like Particle Synthesis to Foster Science Self-efficacy in Students With Minimal Laboratory Experience.
Macie A Proctor-Roser, Marinca Faimau, Julianne Peabody, Krystal R Charley, Bryce Chackerian

Bio Protoc· July 2025

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Immunization with VLP-based vaccines induces high IgG antibody titers in dermal interstitial fluid.
Alexandra Francian, Srinivasa R Gadam, Aidan Leyba, Robert M Taylor, Pavan Muttil, Bryce Chackerian

bioRxiv· June 2025

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pS396/pS404 (PHF1) tau vaccine outperforms pS199/pS202 (AT8) in rTg4510 tauopathy model.
Jonathan P Hulse, Nicole M Maphis, Julianne Peabody, Virginie Bondu, Bryce Chackerian

NPJ Vaccines· May 2025

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Virus-like particle vaccines targeting a key epitope in circumsporozoite protein provide sterilizing immunity against malaria.
Yogesh Nepal, Alexandra Francian, Yevel Flores-Garcia, Bryce T Roberts, Sunil A David, Bryce Chackerian

bioRxiv· May 2025

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Superior Potency of Synthetic Virus-like Structures in Vaccine-Induced Antibody Responses Compared to Qβ Bacteriophage Virus-like Particles.
Alexander R Meyer, Libo Li, Wei-Yun Wholey, Bryce Chackerian, Wei Cheng

Viruses· April 2025

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Targeting of phosphorylated tau at threonine 181 by a Qβ virus-like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaques.
Nicole M Maphis, Jonathan Hulse, Julianne Peabody, Somayeh Dadras, Madelin J Whelpley, Bryce Chackerian

Alzheimers Dement· March 2025

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Two doses of Qβ virus like particle vaccines elicit protective antibodies against heroin and fentanyl.
Isabella G Romano, Brandi Johnson-Weaver, Susan B Core, Andzoa N Jamus, Marcus Brackeen, Bryce Chackerian

NPJ Vaccines· March 2025

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Pathological tau activates inflammatory nuclear factor-kappa B (NF-κB) and pT181-Qβ vaccine attenuates NF-κB in PS19 tauopathy mice.
Karthikeyan Tangavelou, Shanya Jiang, Somayeh Dadras, Jonathan P Hulse, Kathryn Sanchez, Bryce Chackerian

bioRxiv· March 2025

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Virus-like particle-based vaccines targeting the mosquito salivary protein TRIO.
Alexandra Francian, Yevel Flores-Garcia, John R Powell, Nikolai Petrovsky, Fidel Zavala, Bryce Chackerian

mSphere· February 2025

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Formulation, Characterization, and Immunogenicity of Heat-Stabilized Dissolvable Microneedles Containing a Novel VLP Vaccine.
Aidan Leyba, Alexandra Francian, Mohammad Razjmoo, Amelia Bierle, Ranjith Janardhana, Bryce Chackerian

bioRxiv· December 2024

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An Integrated Signaling Threshold Initiates IgG Response toward Virus-like Immunogens.
Wei-Yun Wholey, Alexander R Meyer, Sekou-Tidiane Yoda, James L Mueller, Raisa Mathenge, Bryce Chackerian

J Immunol· October 2024

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An Approach for Antigen-Agnostic Identification of Virus-Like Particle-Displayed Epitopes that Engage Specific Antibody V Gene Regions.
Julianne Peabody, Susan B Core, Larance Ronsard, Daniel Lingwood, David S Peabody, Bryce Chackerian

Methods Mol Biol· September 2024

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Virus-like particle-based vaccines targeting the mosquito salivary protein, TRIO.
Alexandra Francian, Yevel Flores-Garcia, John R Powell, Nikolai Petrovsky, Fidel Zavala, Bryce Chackerian

bioRxiv· September 2024

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A two-dose regimen of Qβ virus-like particle-based vaccines elicit protective antibodies against heroin and fentanyl.
Isabella G Romano, Brandi Johnson-Weaver, Susan B Core, Andzoa N Jamus, Marcus Brackeen, Bryce Chackerian

bioRxiv· August 2024

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Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau pathology and restoring cognitive deficits in the rTg4510 mouse model of tauopathy.
Jonathan Hulse, Nicole Maphis, Julianne Peabody, Bryce Chackerian, Kiran Bhaskar

Res Sq· June 2024

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Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau pathology and restoring cognitive deficits in the rTg4510 mouse model of tauopathy.
Jonathan Hulse, Nicole Maphis, Julianne Peabody, Bryce Chackerian, Kiran Bhaskar

bioRxiv· April 2024

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Minimal Determinants for Lifelong Antiviral Antibody Responses in Mice from a Single Exposure to Virus-like Immunogens at Low Doses.
Wei-Yun Wholey, Alexander R Meyer, Sekou-Tidiane Yoda, Bryce Chackerian, Julie Zikherman

Vaccines (Basel)· April 2024

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PCSK9 vaccines: a promising new strategy for the treatment of hypercholesterolemia?
Bryce Chackerian, Alan T Remaley

J Lipid Res· March 2024

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A bacteriophage virus-like particle vaccine against oxycodone elicits high-titer and long-lasting antibodies that sequester drug in the blood.
Isabella G Romano, Susan B Core, Naomi R Lee, Curtis Mowry, Koen K A Van Rompay, Bryce Chackerian

Vaccine· January 2024

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An integrated signaling threshold initiates IgG response towards virus-like immunogens.
Wei-Yun Wholey, Alexander R Meyer, Sekou-Tidiane Yoda, James L Mueller, Raisa Mathenge, Bryce Chackerian

bioRxiv· January 2024

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A virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in non-human primates.
Alexandra Fowler, Koen K A Van Rompay, Maureen Sampson, Javier Leo, Jennifer K Watanabe, Bryce Chackerian

NPJ Vaccines· September 2023

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A Virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in Non-Human Primates.
Alexandra Fowler, Koen K A Van Rompay, Maureen Sampson, Javier Leo, Jennifer K Watanabe, Bryce Chackerian

bioRxiv· May 2023

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