Publications by authors named "Byung Ha"

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RAF isoform selectivity of MEK inhibitors and rational design of a covalent ARAF-MEK inhibitor.
Sayan Chakraborty, Jie Jiang, Javier Vinals Camallonga, Dimitris Gazgalis, Thomas W Gero, Byung Hak Ha, Michael J Eck

bioRxiv· December 2025

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Structural basis for MEKK2 dimerization and substrate recognition.
Kimberly J Vish, Clotilde Huet-Calderwood, Byung Hak Ha, David A Calderwood, Titus J Boggon

Nat Commun· November 2025

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Characterization and inhibitor sensitivity of ARAF, BRAF, and CRAF kinases.
Emre Tkacik, Dong Man Jang, Kayla Boxer, Byung Hak Ha, Michael J Eck

J Biol Chem· October 2025

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Nickel Binding to the c-Src SH3 Domain Facilitates Crystallization.
Xander Calicdan, Oriana S Fisher, Byung Hak Ha, Titus J Boggon, Amy L Stiegler

Protein Pept Lett· October 2025

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Cryo-EM structures of CRAF/MEK1/14-3-3 complexes in autoinhibited and open-monomer states reveal features of RAF regulation.
Dong Man Jang, Kayla Boxer, Byung Hak Ha, Emre Tkacik, Talya Levitz, Shaun Rawson, Michael J Eck

Nat Commun· September 2025

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Characterization and inhibitor sensitivity of ARAF, BRAF, and CRAF complexes.
Emre Tkacik, Dong Man Jang, Kayla Boxer, Byung Hak Ha, Michael J Eck

bioRxiv· August 2025

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Nickel binding to c-Src SH3 domain facilitates crystallization.
Xander Calicdan, Oriana S Fisher, Byung Hak Ha, Titus J Boggon, Amy L Stiegler

bioRxiv· May 2025

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Correction: Rho family GTPase signaling through type II p21-activated kinases.
Ashwin K Chetty, Byung Hak Ha, Titus J Boggon

Cell Mol Life Sci· October 2023

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Structural and functional characterization of USP47 reveals a hot spot for inhibitor design.
Sang Chul Shin, Jinyoung Park, Kyung Hee Kim, Jung Min Yoon, Jinhong Cho, Byung Hak Ha

Commun Biol· September 2023

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Author Correction: Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4).
Byung Hak Ha, Sezin Yigit, Nalini Natarajan, Elizabeth M Morse, David A Calderwood

Commun Biol· July 2023

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Structure and RAF family kinase isoform selectivity of type II RAF inhibitors tovorafenib and naporafenib.
Emre Tkacik, Kunhua Li, Gonzalo Gonzalez-Del Pino, Byung Hak Ha, Javier Vinals, Michael J Eck

J Biol Chem· May 2023

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Isolation and identification of extracellular matrix proteins from oil-based CASPERized mouse brains for matrisomal analysis.
Byung Geun Ha, Yu-Jin Jang, EunSoo Lee, Byung-Gyu Kim, Kyungjae Myung

Heliyon· April 2023

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Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4).
Byung Hak Ha, Sezin Yigit, Nalini Natarajan, Elizabeth M Morse, David A Calderwood

Commun Biol· November 2022

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Rho family GTPase signaling through type II p21-activated kinases.
Ashwin K Chetty, Byung Hak Ha, Titus J Boggon

Cell Mol Life Sci· November 2022

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Decoherence-Induced Exceptional Points in a Dissipative Superconducting Qubit.
Weijian Chen, Maryam Abbasi, Byung Ha, Serra Erdamar, Yogesh N Joglekar

Phys Rev Lett· March 2022

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Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation.
Gonzalo L Gonzalez-Del Pino, Kunhua Li, Eunyoung Park, Anna M Schmoker, Byung Hak Ha, Michael J Eck

Proc Natl Acad Sci U S A· September 2021

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Depletion of Mitochondrial Components from Extracellular Vesicles Secreted from Astrocytes in a Mouse Model of Fragile X Syndrome.
Byung Geun Ha, Jung-Yoon Heo, Yu-Jin Jang, Tae-Shin Park, Ju-Yeon Choi

Int J Mol Sci· January 2021

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Recognition of physiological phosphorylation sites by p21-activated kinase 4.
Ashwin K Chetty, Joel A Sexton, Byung Hak Ha, Benjamin E Turk, Titus J Boggon

J Struct Biol· September 2020

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Mineral-Enriched Deep-Sea Water Modulates Lactate Metabolism via PGC-1α-Mediated Metabolic Reprogramming.
Byung Geun Ha, Sung Suk Jung, You Kyung Jang, Byong Yeob Jeon, Yun Hee Shon

Mar Drugs· October 2019

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Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output.
Chad J Miller, Hua Jane Lou, Craig Simpson, Bert van de Kooij, Byung Hak Ha, Natasha L Pirman, Jesse Rinehart, Michael B Yaffe

PLoS Biol· March 2019

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PAK4 crystal structures suggest unusual kinase conformational movements.
Eric Y Zhang, Byung Hak Ha, Titus J Boggon

Biochim Biophys Acta Proteins Proteom· February 2018

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The crystal structure of pseudokinase PEAK1 (Sugen kinase 269) reveals an unusual catalytic cleft and a novel mode of kinase fold dimerization.
Byung Hak Ha, Titus J Boggon

J Biol Chem· February 2018

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Structural basis for Ufm1 recognition by UfSP.
Kyung Hee Kim, Byung Hak Ha, Eunice EunKyeong Kim

FEBS Lett· January 2018

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CDC42 binds PAK4 via an extended GTPase-effector interface.
Byung Hak Ha, Titus J Boggon

Proc Natl Acad Sci U S A· January 2018

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Effects of proton beam irradiation on mitochondrial biogenesis in a human colorectal adenocarcinoma cell line.
Byung Geun Ha, Sung Suk Jung, Yun Hee Shon

Int J Oncol· September 2017

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