Publications by authors named "Michael B Yaffe"

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Change in novel plasmin activated clotting time assay predicts hyperfibrinolysis, massive transfusion, and mortality in trauma in under 3 minutes.
Elizabeth R Maginot, Hunter B Moore, Ernest E Moore, Nicolle K Barmettler, Trace B Moody, Michael B Yaffe

Am J Surg· December 2025

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A rebrand for proteasome inhibition in solid tumors via continuous hepatic artery infusion.
Carolina M Larrain, Jack H Victory, Priyanka P Desai, Lindsay R Friedman, Hannah Stepp, Michael B Yaffe

JCI Insight· December 2025

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A simple circuit to sustain intact tumor microenvironments for complex drug interrogations.
A Leila Sarvestani, Samantha Ruff, Kirsten Remmert, Martha Teke, Emily Verbus, Michael B Yaffe

bioRxiv· October 2025

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NC410, a bivalent LAIR-2 construct, remodels collagen in the tumor microenvironment and abrogates neutrophil-driven T cell suppression.
Thejaswini Giridharan, Sora Suzuki, Anm Nazmul H Khan, Qian Liu, Kristopher Attwood, Michael B Yaffe

J Immunol· September 2025

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Expression of IMPACT Curtails Metabolic Plasticity and Augments NK Cell Killing to Abrogate Metastatic Growth.
Surajit Sinha, Abir Kumar Panda, Rodrigo Xavier das Neves, Zeribe C Nwosu, Ke Xu, Michael B Yaffe

Cancer Discov· September 2025

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Expression of IMPACT curtails metabolic plasticity and augments NK cell killing to abrogate metastatic growth.
Surajit Sinha, Abir Kumar Panda, Rodrigo Xavier das Neves, Zeribe C Nwosu, Ke Xu, Michael B Yaffe

Cancer Discov· July 2025

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Plasminogen supplementation improves lysis of inflammatory retained traumatic hemothorax.
Elizabeth R Maginot, Flobater I Gawargi, Ernest E Moore, Collin M White, Grace E Volk, Michael B Yaffe

J Trauma Acute Care Surg· June 2025

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Structural Identification of Major Molecular Determinants for Phosphotyrosine Recognition in Tyrosine Kinases Reveals Tumour Promoting and Suppressive Functions.
Nuo Cheng, Luis R Millán-Barea, Marc Creixell, Alexis R Barr, Yi Wen Kong, Michael B Yaffe

bioRxiv· June 2025

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Signal amplification by cyclic extension enables high-sensitivity single-cell mass cytometry.
Xiao-Kang Lun, Kuanwei Sheng, Xueyang Yu, Ching Yeung Lam, Gokul Gowri, Michael B Yaffe

Nat Biotechnol· May 2025

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Cell cycle dysregulation in cancer.
Antonino Glaviano, Samarendra K Singh, E Hui Clarissa Lee, Elena Okina, Hiu Yan Lam, Michael B Yaffe

Pharmacol Rev· March 2025

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Response.
Christopher D Barrett, Peter K Moore, Michael B Yaffe

Chest· February 2025

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Neutrophil-Mediated Inflammatory Plasminogen Degradation, Rather Than High Plasminogen-Activator Inhibitor-1, May Underly Failures and Inefficiencies of Intrapleural Fibrinolysis.
Christopher D Barrett, Peter K Moore, Ernest E Moore, Hunter B Moore, James G Chandler, Michael B Yaffe

Chest· January 2025

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An RNA damage response network mediates the lethality of 5-FU in colorectal cancer.
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Michael B Yaffe

Cell Rep Med· October 2024

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The Fanconi anemia core complex promotes CtIP-dependent end resection to drive homologous recombination at DNA double-strand breaks.
Bert van de Kooij, Fenna J van der Wal, Magdalena B Rother, Wouter W Wiegant, Pau Creixell, Michael B Yaffe

Nat Commun· August 2024

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The intrinsic substrate specificity of the human tyrosine kinome.
Tomer M Yaron-Barir, Brian A Joughin, Emily M Huntsman, Alexander Kerelsky, Daniel M Cizin, Michael B Yaffe

Nature· May 2024

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Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis.
Ting Dong, Guangan Hu, Zhongqi Fan, Huirui Wang, Yinghui Gao, Michael B Yaffe

Nat Commun· January 2024

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Early Immune Changes Support Signet Ring Cell Dormancy in CDH1-Driven Hereditary Diffuse Gastric Carcinogenesis.
Benjamin L Green, Lauren A Gamble, Laurence P Diggs, Darryl Nousome, Jesse C Patterson, Michael B Yaffe

Mol Cancer Res· December 2023

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The Fanconi anemia core complex promotes CtIP-dependent end-resection to drive homologous recombination at DNA double-strand breaks.
Bert van de Kooij, Fenna J van der Wal, Magdalena B Rother, Pau Creixell, Merula Stout, Michael B Yaffe

bioRxiv· September 2023

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The mission to ensure continued funding for excellent basic research.
Angus I Lamond, Ivan Dikic, Andre Nussenzweig, Christoph W Müller, Janet M Thornton, Michael B Yaffe

EMBO Rep· July 2023

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Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition.
Tatiana S Netterfield, Gerard J Ostheimer, Andrea R Tentner, Brian A Joughin, Alexandra M Dakoyannis, Michael B Yaffe

Cell Syst· July 2023

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MAPKAP Kinase-2 phosphorylation of PABPC1 controls its interaction with 14-3-3 proteins after DNA damage: A combined kinase and protein array approach.
Justine R Stehn, Scott R Floyd, Erik W Wilker, H Christian Reinhardt, Scott M Clarke, Michael B Yaffe

Front Mol Biosci· April 2023

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An RNA Damage Response Network Mediates the Lethality of 5-FU in Clinically Relevant Tumor Types.
Jung-Kuei Chen, Karl A Merrick, Yi Wen Kong, Anita Izrael-Tomasevic, George Eng, Michael B Yaffe

bioRxiv· April 2023

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Neutrophil heterogeneity and emergence of a distinct population of CD11b/CD18-activated low-density neutrophils after trauma.
Ingred Goretti Riça, Brian A Joughin, Martha E Teke, Tiffany R Emmons, Alec M Griffith, Michael B Yaffe

J Trauma Acute Care Surg· February 2023

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Seeing is great, understanding is better.
H Holden Thorp, Michael B Yaffe

Sci Signal· January 2023

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An atlas of substrate specificities for the human serine/threonine kinome.
Jared L Johnson, Tomer M Yaron, Emily M Huntsman, Alexander Kerelsky, Junho Song, Michael B Yaffe

Nature· January 2023

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